Mitochondrial tiglyl-CoA is hydrolyzed to form alpha-methyl-beta-hydroxybutyryl-CoA. While crude extracts of human liver cells have been shown to catalyze the reaction, the specific enzyme responsible for it has not been identified (Sweetman and Williams 2001).
Beaudet, AL, Scriver, CR, Sly, WS, Valle, D
enoyl-CoA hydratase activity of enoyl-CoA hydratase [mitochondrial matrix]
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