Reactome | GLS2 [mitochondrial matrix]

GLS2 [mitochondrial matrix]

Stable Identifier

R-HSA-70610

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

mitochondrial matrix

Synonyms

glutaminase 2, Glutaminase, liver isoform, mitochondrial precursor

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q9UI32 GLS2

Gene Names

GLS2, GA

Chain

transit peptide:1-14, chain:15-602

Reference Genes

BioGPS Gene:27165 GLS2

COSMIC (genes):GLS2 GLS2

CTD Gene:27165 GLS2

dbSNP Gene:27165 GLS2

ENSEMBL:ENSG00000135423 GLS2

HGNC:29570 GLS2

KEGG Gene (Homo sapiens):27165 GLS2

Monarch:27165 GLS2

NCBI Gene:27165 GLS2

OMIM:606365 GLS2

UCSC:Q9UI32 GLS2

Reference Transcript

Other Identifiers

0004280400

0006400746

11747633_a_at

11753078_a_at

11756498_a_at

11762122_a_at

11762123_at

11762124_x_at

1564706_s_at

16766185

205531_s_at

27165

3457890

3457892

3457893

3457894

3457895

3457897

3457899

3457901

3457903

3457904

3457905

3457906

3457907

3457908

3457909

3457910

3457912

3457913

3457914

3457915

3457917

3457918

3457919

3457924

3457925

35711_at

7964183

A_24_P326739

GE552452

GE58509

GO:0003674

GO:0004359

GO:0005515

GO:0005575

GO:0005622

GO:0005737

GO:0005739

GO:0005759

GO:0006520

GO:0006537

GO:0006541

GO:0006543

GO:0006810

GO:0008150

GO:0008219

GO:0008652

GO:0009056

GO:0009058

GO:0014047

GO:0016787

GO:0016810

GO:0042981

GO:0043226

GO:0044281

GO:0072593

ILMN_1677439

ILMN_1706070

ILMN_1709771

PH_hs_0023088

g7019388_3p_a_at

Participant Of

hasComponent

GLS2 dimer [mitochondrial matrix]

Inferred To

gls2 [mitochondrial matrix] (Xenopus tropicalis)

gls2a [mitochondrial matrix] (Danio rerio)

GLS [mitochondrial matrix] (Drosophila melanogaster)

glna-3 [mitochondrial matrix] (Caenorhabditis elegans)

GLS2 [mitochondrial matrix] (Bos taurus)

GLS2 [mitochondrial matrix] (Canis familiaris)

GLS2 [mitochondrial matrix] (Sus scrofa)

Gls2 [mitochondrial matrix] (Mus musculus)

Gls2 [mitochondrial matrix] (Rattus norvegicus)

Cross References

RefSeq

NP_001267727.1, NP_037399.2

OpenTargets

ENSG00000135423

IntEnz

3.5.1.2

GeneCards

Q9UI32

HPA

ENSG00000135423-GLS2

Ensembl

ENST00000311966, ENSP00000419661, ENSP00000310447, ENST00000486896, ENSG00000135423

PRO

Q9UI32

HMDB Protein

HMDBP00675

PDB

4BQM, 5U0K

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q6GPH4 XAF1	1	XAF1 [cytosol] (R-HSA-1015680)	0.556	3