Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
ASL [cytosol]
Stable Identifier
R-HSA-70570
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
argininosuccinate lyase, arginosuccinase
Locations in the PathwayBrowser
Expand all
Metabolism (Homo sapiens)
Metabolism of amino acids and derivatives (Homo sapiens)
Urea cycle (Homo sapiens)
argininosuccinate <=> fumarate + arginine (Homo sapiens)
ASL tetramer [cytosol] (Homo sapiens)
ASL [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:P04424 ASL
Gene Names
ASL
Chain
initiator methionine:, chain:2-464
Reference Genes
BioGPS Gene:435 ASL
COSMIC (genes):ASL ASL
CTD Gene:435 ASL
dbSNP Gene:435 ASL
ENSEMBL:ENSG00000126522 ASL
ENSEMBL_homo_sapiens_GENE:ENSG00000126522.17 ASL
HGNC:746 ASL
KEGG Gene (Homo sapiens):435 ASL
Monarch:435 ASL
NCBI Gene:435 ASL
OMIM:608310 ASL
UCSC:P04424 ASL
Reference Transcript
RefSeq:NM_001024943.1 ASL
RefSeq:NM_000048.3 ASL
RefSeq:NM_001024944.1 ASL
Other Identifiers
11720822_a_at
11740232_x_at
11742937_x_at
11746742_a_at
17046601
204608_PM_at
204608_at
3005364
3005365
3005366
3005367
3005368
3005373
3005374
3005375
3005377
3005379
3005383
3005385
3005387
3005389
3005391
3005394
3005397
3005399
3005403
3005405
3005406
3005407
3005408
3005409
3005410
36528_at
435
8133122
GO:0000050
GO:0003824
GO:0004056
GO:0005515
GO:0005576
GO:0005615
GO:0005737
GO:0005829
GO:0006520
GO:0006525
GO:0006526
GO:0007626
GO:0008652
GO:0009791
GO:0016829
GO:0019676
GO:0042450
GO:0042802
GO:0043226
GO:0044281
GO:0045429
GO:0048856
GO:0070062
GO:0071941
HMNXSV003015004
ILMN_1685037
ILMN_1685142
ILMN_2379393
M14218_at
PH_hs_0025846
PH_hs_0033478
TC07003307.hg
g4502256_3p_at
Participates
as a component of
ASL tetramer [cytosol] (Homo sapiens)
Inferred To
Argl [cytosol]
(Drosophila melanogaster)
asl [cytosol]
(Danio rerio)
asl [cytosol]
(Xenopus tropicalis)
ASL [cytosol]
(Bos taurus)
ASL [cytosol]
(Canis familiaris)
ASL [cytosol]
(Gallus gallus)
ASL [cytosol]
(Mus musculus)
ASL [cytosol]
(Rattus norvegicus)
ASL [cytosol]
(Saccharomyces cerevisiae)
ASL [cytosol]
(Schizosaccharomyces pombe)
ASL [cytosol]
(Sus scrofa)
Cross References
RefSeq
NP_001020114.1
,
NP_000039.2
,
NP_001020115.1
OpenTargets
ENSG00000126522
GeneCards
P04424
HPA
ENSG00000126522-ASL
Ensembl
ENST00000673518
,
ENSP00000378740
,
ENST00000380839
,
ENSP00000499889
,
ENSP00000378741
,
ENST00000395332
,
ENST00000304874
,
ENSG00000126522
,
ENST00000395331
,
ENSP00000370219
,
ENSP00000307188
PRO
P04424
Pharos - Targets
P04424
Orphanet
15957
HMDB Protein
HMDBP00697
PDB
1K62
,
1AOS
© 2024
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text