Reactome | G6PD dimer [cytosol]

G6PD dimer [cytosol]

Stable Identifier

R-HSA-70373

Type

Complex

Species

Homo sapiens

Compartment

cytosol

Synonyms

glucose-6-phosphate 1-dehydrogenase dimer

Locations in the PathwayBrowser

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Cellular responses to stimuli (Homo sapiens)

- Cellular responses to stress (Homo sapiens)
  - Cellular response to chemical stress (Homo sapiens)
    - KEAP1-NFE2L2 pathway (Homo sapiens)
      - Nuclear events mediated by NFE2L2 (Homo sapiens)
        
        NFE2L2 regulates pentose phosphate pathway genes (Homo sapiens)
        
        AcK-NFE2L2-dependent P6GD gene expression (Homo sapiens)
        
        G6PD dimer and tetramer [cytosol] (Homo sapiens)
        
        G6PD dimer [cytosol] (Homo sapiens)

Literature References

PubMed ID	Title	Journal	Year
10745013	Human glucose-6-phosphate dehydrogenase: the crystal structure reveals a structural NADP(+) molecule and provides insights into enzyme deficiency Lam, VM, Adams, MJ, Au, SW, Gover, S	Structure	2000

Participants

components

x 2 G6PD [cytosol] (Homo sapiens)
x 2 NADP+ [cytosol]

Participates

as a member of

G6PD dimer and tetramer [cytosol] (Homo sapiens)

Inferred To

G6PD dimer [cytosol] (Bos taurus)

G6PD dimer [cytosol] (Caenorhabditis elegans)

G6PD dimer [cytosol] (Canis familiaris)

G6PD dimer [cytosol] (Dictyostelium discoideum)

G6PD dimer [cytosol] (Drosophila melanogaster)

G6PD dimer [cytosol] (Mus musculus)

G6PD dimer [cytosol] (Plasmodium falciparum)

G6PD dimer [cytosol] (Rattus norvegicus)

G6PD dimer [cytosol] (Saccharomyces cerevisiae)

G6PD dimer [cytosol] (Schizosaccharomyces pombe)

G6PD dimer [cytosol] (Sus scrofa)

G6PD dimer [cytosol] (Xenopus tropicalis)

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