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G6PD [cytosol]
Stable Identifier
R-HSA-70372
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Glucose-6-phosphate 1-dehydrogenase
Locations in the PathwayBrowser
Expand all
Cellular responses to stimuli (Homo sapiens)
Cellular responses to stress (Homo sapiens)
Cellular response to chemical stress (Homo sapiens)
KEAP1-NFE2L2 pathway (Homo sapiens)
Nuclear events mediated by NFE2L2 (Homo sapiens)
NFE2L2 regulates pentose phosphate pathway genes (Homo sapiens)
AcK-NFE2L2-dependent P6GD gene expression (Homo sapiens)
G6PD dimer and tetramer [cytosol] (Homo sapiens)
G6PD dimer [cytosol] (Homo sapiens)
G6PD [cytosol] (Homo sapiens)
G6PD tetramer [cytosol] (Homo sapiens)
G6PD [cytosol] (Homo sapiens)
Gene expression (Transcription) (Homo sapiens)
RNA Polymerase II Transcription (Homo sapiens)
Generic Transcription Pathway (Homo sapiens)
Transcriptional Regulation by TP53 (Homo sapiens)
TP53 Regulates Metabolic Genes (Homo sapiens)
alpha-D-glucose 6-phosphate + NADP+ => D-glucono-1,5-lactone 6-phosphate + NADPH + H+ (Homo sapiens)
G6PD dimer and tetramer [cytosol] (Homo sapiens)
G6PD dimer [cytosol] (Homo sapiens)
G6PD [cytosol] (Homo sapiens)
G6PD tetramer [cytosol] (Homo sapiens)
G6PD [cytosol] (Homo sapiens)
Metabolism (Homo sapiens)
Metabolism of carbohydrates (Homo sapiens)
Pentose phosphate pathway (Homo sapiens)
alpha-D-glucose 6-phosphate + NADP+ => D-glucono-1,5-lactone 6-phosphate + NADPH + H+ (Homo sapiens)
G6PD dimer and tetramer [cytosol] (Homo sapiens)
G6PD dimer [cytosol] (Homo sapiens)
G6PD [cytosol] (Homo sapiens)
G6PD tetramer [cytosol] (Homo sapiens)
G6PD [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:P11413 G6PD
Gene Names
G6PD
Chain
initiator methionine:, chain:2-515
Reference Genes
BioGPS Gene:2539 G6PD
COSMIC (genes):G6PD G6PD
CTD Gene:2539 G6PD
dbSNP Gene:2539 G6PD
ENSEMBL:ENSG00000160211 G6PD
HGNC:4057 G6PD
KEGG:hsa:2539 G6PD
Monarch:2539 G6PD
NCBI Gene:2539 G6PD
OMIM:305900 G6PD
UCSC:P11413 G6PD
Reference Transcript
RefSeq:NM_000402.4 G6PD
RefSeq:NM_001042351.2 G6PD
Other Identifiers
11716292_a_at
11716293_x_at
11752486_a_at
1570297_PM_at
1570297_at
17115636
202275_PM_at
202275_at
2539
4027412
4027414
4027415
4027417
4027418
4027419
4027420
4027421
4027422
4027423
4027424
4027425
4027426
4027427
4027428
4027429
4027430
4027431
4027432
4027433
4027434
4027435
4027436
4027437
4027438
4027439
4027440
4027441
4027442
4027443
4027444
4027446
4027447
4027448
4027449
4027450
4027451
4027452
8176133
A_23_P34093
A_24_P913947
GE59654
GE903116
GO:0003824
GO:0004345
GO:0005515
GO:0005536
GO:0005737
GO:0005829
GO:0005975
GO:0006006
GO:0006091
GO:0006098
GO:0006575
GO:0006629
GO:0006695
GO:0006739
GO:0006740
GO:0006749
GO:0006790
GO:0009051
GO:0009898
GO:0010041
GO:0010734
GO:0014070
GO:0016020
GO:0016491
GO:0016614
GO:0019322
GO:0021762
GO:0030246
GO:0032094
GO:0034451
GO:0034599
GO:0042802
GO:0042803
GO:0043226
GO:0043231
GO:0043249
GO:0043523
GO:0045471
GO:0046390
GO:0048856
GO:0050661
GO:0051156
GO:0055086
GO:0061052
GO:0070062
GO:1901135
GO:1904879
GO:2000378
HMNXSV003000973
HMNXSV003040996
Hs2.382019.1.S1_3p_at
ILMN_1697559
ILMN_1849039
ILMN_2261122
ILMN_2347949
PH_hs_0004621
TC0X001538.hg
TC0X002293.hg
TC0X002294.hg
X55448_cds1_s_at
g4503844_3p_at
p17119
Participates
as a component of
G6PD tetramer [cytosol] (Homo sapiens)
G6PD dimer [cytosol] (Homo sapiens)
Inferred To
g6pd [cytosol]
(Xenopus tropicalis)
G6PD [cytosol]
(Bos taurus)
G6PD [cytosol]
(Caenorhabditis elegans)
G6PD [cytosol]
(Canis familiaris)
G6PD [cytosol]
(Dictyostelium discoideum)
G6PD [cytosol]
(Drosophila melanogaster)
G6PD [cytosol]
(Mus musculus)
G6PD [cytosol]
(Plasmodium falciparum)
G6PD [cytosol]
(Rattus norvegicus)
G6PD [cytosol]
(Saccharomyces cerevisiae)
G6PD [cytosol]
(Schizosaccharomyces pombe)
G6PD [cytosol]
(Sus scrofa)
Cross References
RefSeq
NP_000393.4
,
NP_001035810.1
ZINC - World Drugs
G6PD_HUMAN
OpenTargets
ENSG00000160211
ENSEMBL
ENSP00000358633
,
ENSP00000377192
,
ENST00000696429
,
ENSP00000377194
,
ENST00000393564
,
ENST00000369620
,
ENST00000393562
,
ENST00000696430
,
ENSP00000512625
,
ENSP00000512624
ZINC - FDA approved
G6PD_HUMAN
ZINC - Substances
G6PD_HUMAN
ZINC - Biogenic
G6PD_HUMAN
ZINC target
P11413
PRO
P11413
GlyGen
P11413
PDB
7SNG
,
6E07
,
6VA7
,
1QKI
,
7SEH
,
7TOF
,
7SNI
,
7SNF
,
6E08
,
6VA0
,
7UC2
,
6VA8
,
5UKW
,
7SNH
,
7TOE
,
6VA9
,
7ZVD
,
7UAG
,
7UAL
,
6JYU
,
6VAQ
,
7SEI
,
2BH9
,
2BHL
ZINC - Investigational
G6PD_HUMAN
ZINC - Metabolites
G6PD_HUMAN
HPA
ENSG00000160211-G6PD
Pharos - Targets
P11413
Orphanet
G6PD
ZINC - Predictions - Purchasable
G6PD_HUMAN
HMDB Protein
HMDBP00328
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q8IXJ6 SIRT2
1
SIRT2 [cytosol]
(R-HSA-2161118)
0.524
3
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