GALK1 phosphorylates Gal to Gal1P

Stable Identifier
R-HSA-70355
Type
Reaction [transition]
Species
Homo sapiens
Compartment
cytosol
Synonyms
ATP + alpha-D-galactose => ADP + alpha-D-galactose 1-phosphate + H(+)
ReviewStatus
5/5
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GALK1 phosphorylates Gal to Gal1P
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Cytosolic galactokinase (GALK1) catalyses the reaction of ATP and D-galactose to form ADP and D-galactose 1-phosphate (Ai at al. 1995).
Literature References
PubMed ID Title Journal Year
7542884 Comparison of the enzymatic activities of human galactokinase GALK1 and a related human galactokinase protein GK2

Basu, M, Bergsma, DJ, Ai, Y, Stambolian, D

Biochem Biophys Res Commun 1995
Participants
Input
Output
Participates
as an event of
Catalyst Activity

galactokinase activity of GALK1 [cytosol]

Physical Entity
GALK1 [cytosol] (Homo sapiens)
Activity
galactokinase activity (GO:0004335)
Orthologous Events
GALK1 phosphorylates Gal to Gal1P (Bos taurus)
GALK1 phosphorylates Gal to Gal1P (Canis familiaris)
GALK1 phosphorylates Gal to Gal1P (Danio rerio)
GALK1 phosphorylates Gal to Gal1P (Gallus gallus)
GALK1 phosphorylates Gal to Gal1P (Mus musculus)
GALK1 phosphorylates Gal to Gal1P (Rattus norvegicus)
GALK1 phosphorylates Gal to Gal1P (Sus scrofa)
GALK1 phosphorylates Gal to Gal1P (Xenopus tropicalis)
Cross References
RHEA
Reviewed
D'Eustachio, P  (2025-01-23)
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