lipo-K132,K259-DLAT [mitochondrial matrix]

Stable Identifier
R-HSA-69969
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
mitochondrial matrix
Synonyms
pyruvate dehydrogenase E2 subunit, Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex, ODP2_HUMAN, Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial precursor , E2, PDC-E2, 70 kDa mitochondrial autoantigen of primary biliary cirrhosis, PBC, M2 antigen complex 70 kDa subunit
Locations in the PathwayBrowser
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External Reference Information
External Reference
UniProt:P10515 DLAT
Gene Names
DLAT, DLTA
Chain
transit peptide:1-86, chain:87-647
Reference Genes
BioGPS Gene:1737 DLAT
COSMIC (genes):DLAT DLAT
CTD Gene:1737 DLAT
dbSNP Gene:1737 DLAT
ENSEMBL:ENSG00000150768 DLAT
HGNC:2896 DLAT
KEGG Gene (Homo sapiens):1737 DLAT
Monarch:1737 DLAT
NCBI Gene:1737 DLAT
OMIM:608770 DLAT
Reference Transcript
Other Identifiers
0004810671
11727791_s_at
11727792_at
11727793_x_at
11750801_a_at
11751002_x_at
11752995_a_at
16731169
1737
211150_s_at
212568_s_at
213149_at
3348855
3348856
3348857
3348858
3348859
3348861
3348863
3348864
3348866
3348867
3348868
3348869
3348870
3348872
3348874
3348875
3348876
3348879
3348881
3348883
3348884
3348885
3348886
3348887
39041_at
7943827
84706_at
A_14_P133023
A_23_P203030
A_24_P372672
GE60238
GO:0003674
GO:0004742
GO:0005515
GO:0005575
GO:0005622
GO:0005737
GO:0005739
GO:0005759
GO:0005967
GO:0005975
GO:0006006
GO:0006086
GO:0006090
GO:0006091
GO:0006099
GO:0006464
GO:0006790
GO:0008150
GO:0009058
GO:0016491
GO:0016740
GO:0016746
GO:0018215
GO:0030431
GO:0030523
GO:0032991
GO:0034604
GO:0034641
GO:0042802
GO:0043226
GO:0043231
GO:0044281
GO:0045254
HMNXSV003028237
Hs.115285.1.S1_3p_a_at
ILMN_1706583
ILMN_1736237
PH_hs_0006319
TC11001005.hg
TC11002866.hg
Y00978_at
g619443_3p_a_at
Participates
as a component of
Other forms of this molecule
DLAT [mitochondrial matrix]
Inferred To
muc [mitochondrial matrix] (Drosophila melanogaster)
pdhC [mitochondrial matrix] (Dictyostelium discoideum)
Dlat [mitochondrial matrix] (Mus musculus)
Dlat [mitochondrial matrix] (Rattus norvegicus)
LAT1 [mitochondrial matrix] (Saccharomyces cerevisiae)
dlat [mitochondrial matrix] (Danio rerio)
dlat-1 [mitochondrial matrix] (Caenorhabditis elegans)
DLAT [mitochondrial matrix] (Gallus gallus)
DLAT [mitochondrial matrix] (Sus scrofa)
lat1 [mitochondrial matrix] (Schizosaccharomyces pombe)
Modified Residues
Name
N6-lipoyl-L-lysine at 132
Coordinate
132
PsiMod Name
N6-lipoyl-L-lysine [MOD:00127]
PsiMod Definition
A protein modification that effectively converts an L-lysine residue to N6-lipoyl-L-lysine.
Name
N6-lipoyl-L-lysine at 259
Coordinate
259
PsiMod Name
N6-lipoyl-L-lysine [MOD:00127]
PsiMod Definition
A protein modification that effectively converts an L-lysine residue to N6-lipoyl-L-lysine.
Cross References
RefSeq
OpenTargets
HPA
GeneCards
Ensembl
PRO
Pharos - Targets
GlyGen
Orphanet
HMDB Protein
PDB
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