Lipo-K259-DLAT [mitochondrial matrix]

Stable Identifier
R-HSA-69969
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
mitochondrial matrix
Synonyms
pyruvate dehydrogenase E2 subunit, Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex, ODP2_HUMAN, Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial precursor , E2, PDC-E2, 70 kDa mitochondrial autoantigen of primary biliary cirrhosis, PBC, M2 antigen complex 70 kDa subunit
Locations in the PathwayBrowser
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External Reference Information
External Reference
UniProt:P10515 DLAT
Gene Names
DLAT, DLTA
Chain
transit peptide:1-86, chain:87-647
Reference Genes
BioGPS Gene:1737 DLAT
COSMIC (genes):DLAT DLAT
CTD Gene:1737 DLAT
dbSNP Gene:1737 DLAT
ENSEMBL:ENSG00000150768 DLAT
HGNC:2896 DLAT
KEGG:hsa:1737 DLAT
Monarch:1737 DLAT
NCBI Gene:1737 DLAT
OMIM:608770 DLAT
UCSC:P10515 DLAT
Reference Transcript
Other Identifiers
11727791_s_at
11727792_at
11727793_x_at
11750801_a_at
11751002_x_at
11752995_a_at
16731169
1737
211150_PM_s_at
211150_s_at
212568_PM_s_at
212568_s_at
213149_PM_at
213149_at
3348854
3348855
3348856
3348857
3348858
3348859
3348860
3348861
3348863
3348864
3348866
3348867
3348868
3348869
3348870
3348871
3348872
3348874
3348875
3348876
3348879
3348881
3348882
3348883
3348884
3348885
3348886
3348887
3348889
3348890
39041_at
7943827
84706_at
A_14_P104374
A_14_P133023
A_23_P203030
A_24_P281923
A_24_P372672
GE60238
GE722720
GO:0003824
GO:0004742
GO:0005515
GO:0005739
GO:0005759
GO:0005975
GO:0006006
GO:0006086
GO:0006090
GO:0006099
GO:0006790
GO:0016407
GO:0016491
GO:0016740
GO:0016746
GO:0034604
GO:0042802
GO:0043226
GO:0043231
GO:0045254
GO:0055086
GO:0140096
GO:1901135
HMNXSV003028237
Hs.115285.1.S1_3p_a_at
ILMN_1706583
PH_hs_0006319
TC11001005.hg
TC11002866.hg
Y00978_at
g619443_3p_a_at
Participates
as an input of
as an output of
as a component of
Other forms of this molecule
AcetyllipoH2-K132,K259-DLAT [mitochondrial matrix]
LipoH2-K259-DLAT [mitochondrial matrix]
DLAT [mitochondrial matrix]
Inferred To
pdhC [mitochondrial matrix] (Dictyostelium discoideum)
Dlat [mitochondrial matrix] (Drosophila melanogaster)
LAT1 [mitochondrial matrix] (Saccharomyces cerevisiae)
Lipo-K259-DLAT [mitochondrial matrix] (Bos taurus)
Lipo-K259-DLAT [mitochondrial matrix] (Gallus gallus)
Lipo-K259-DLAT [mitochondrial matrix] (Mus musculus)
Lipo-K259-DLAT [mitochondrial matrix] (Plasmodium falciparum)
Lipo-K259-DLAT [mitochondrial matrix] (Rattus norvegicus)
dlat [mitochondrial matrix] (Danio rerio)
dlat [mitochondrial matrix] (Xenopus tropicalis)
dlat-1 [mitochondrial matrix] (Caenorhabditis elegans)
DLAT [mitochondrial matrix] (Canis familiaris)
DLAT [mitochondrial matrix] (Sus scrofa)
lat1 [mitochondrial matrix] (Schizosaccharomyces pombe)
Modified Residues
Name
N6-lipoyl-L-lysine at 259
Coordinate
259
PsiMod Name
N6-lipoyl-L-lysine [MOD:00127]
PsiMod Definition
A protein modification that effectively converts an L-lysine residue to N6-lipoyl-L-lysine.
Cross References
RefSeq
OpenTargets
ENSEMBL
IntEnz
HPA
GeneCards
PRO
Pharos - Targets
Orphanet
GlyGen
HMDB Protein
PDB
Interactors (7)
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