lipo-K132,K259-DLAT [mitochondrial matrix]

Stable Identifier
R-HSA-69969
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
mitochondrial matrix
Synonyms
pyruvate dehydrogenase E2 subunit, Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex, ODP2_HUMAN, Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial precursor , E2, PDC-E2, 70 kDa mitochondrial autoantigen of primary biliary cirrhosis, PBC, M2 antigen complex 70 kDa subunit
Locations in the PathwayBrowser
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External Reference Information
External Reference
UniProt:P10515 DLAT
Gene Names
DLAT, DLTA
Chain
transit peptide:1-86, chain:87-647
Reference Genes
BioGPS Gene:1737 DLAT
COSMIC (genes):DLAT DLAT
CTD Gene:1737 DLAT
dbSNP Gene:1737 DLAT
ENSEMBL:ENSG00000150768 DLAT
HGNC:2896 DLAT
KEGG Gene (Homo sapiens):1737 DLAT
Monarch:1737 DLAT
NCBI Gene:1737 DLAT
OMIM:608770 DLAT
Reference Transcript
Other Identifiers
00010+2.3.1.12
00020+2.3.1.12
0004810671
00620+2.3.1.12
11727791_s_at
11727792_at
11727793_x_at
11750801_a_at
11751002_x_at
11752995_a_at
16731169
1737
1FYC
1Y8N
1Y8O
1Y8P
211150_s_at
212568_s_at
213149_at
2DNE
2PNR
2Q8I
3348854
3348855
3348856
3348857
3348858
3348859
3348861
3348863
3348864
3348866
3348867
3348868
3348869
3348870
3348872
3348874
3348875
3348876
3348879
3348881
3348883
3348884
3348885
3348886
3348887
3782
39041_at
3B8K
3CRK
3CRL
40786
62766
6CT0
7943827
84706_at
A_14_P104374
A_14_P133023
A_23_P203030
A_24_P281923
A_24_P372672
AAA62253
AAH39084
ACA05975
AK057299
AK223596
AP000907
BAD97316
BAG51900
BC039084
CAA68787
CAB003782
CCDS8354
DLAT
DLAT-201
E9PEJ4
E9PKC7
EF444972
ENSG00000150768
ENSP00000280346
ENST00000280346
ENST00000280346.10
EntrezGene:1737
EntrezGene:DLAT
g619443_3p_a_at
GE60238
GO:0003674
GO:0004742
GO:0005515
GO:0005575
GO:0005622
GO:0005623
GO:0005737
GO:0005739
GO:0005759
GO:0005967
GO:0005975
GO:0006006
GO:0006086
GO:0006090
GO:0006091
GO:0006099
GO:0006790
GO:0008150
GO:0009058
GO:0016491
GO:0016740
GO:0016746
GO:0030431
GO:0030523
GO:0032991
GO:0034604
GO:0034641
GO:0042802
GO:0043226
GO:0044281
GO:0045254
GO:0051186
H0YDD4
HGNC:2896
HPA040786
HPA062766
Hs.115285.1.S1_3p_a_at
ILMN_1706583
ILMN_1736237
IPR000089
IPR001078
IPR003016
IPR004167
IPR006257
IPR011053
IPR023213
IPR036625
J03866
MIM:245348
MIM:608770
NM_001931
NP_001922
PF00198
PF00364
PF02817
PH_hs_0006319
Q86YI5
TC11001005.hg
TC11002866.hg
UPI000000D963
XM_011542647
XP_011540949
Y00978
Y00978_at
Participant Of
hasComponent
Other forms of this molecule
DLAT [mitochondrial matrix]
Inferred To
lipo-K132,K259-DLAT [mitochondrial matrix] (Bos taurus)
lipo-K132,K259-DLAT [mitochondrial matrix] (Caenorhabditis elegans)
lipo-K132,K259-DLAT [mitochondrial matrix] (Danio rerio)
lipo-K132,K259-DLAT [mitochondrial matrix] (Dictyostelium discoideum)
lipo-K132,K259-DLAT [mitochondrial matrix] (Drosophila melanogaster)
lipo-K132,K259-DLAT [mitochondrial matrix] (Gallus gallus)
lipo-K132,K259-DLAT [mitochondrial matrix] (Mus musculus)
lipo-K132,K259-DLAT [mitochondrial matrix] (Rattus norvegicus)
lipo-K132,K259-DLAT [mitochondrial matrix] (Saccharomyces cerevisiae)
lipo-K132,K259-DLAT [mitochondrial matrix] (Schizosaccharomyces pombe)
lipo-K132,K259-DLAT [mitochondrial matrix] (Sus scrofa)
lipo-K132,K259-DLAT [mitochondrial matrix] (Xenopus tropicalis)
Homologues of lipo-K132,K259-DLAT [mitochondrial matrix] (Bos taurus)
Modified Residues
Name
N6-lipoyl-L-lysine at 132
Coordinate
132
PsiMod Name
N6-lipoyl-L-lysine [MOD:00127]
PsiMod Definition
A protein modification that effectively converts an L-lysine residue to N6-lipoyl-L-lysine.
Name
N6-lipoyl-L-lysine at 259
Coordinate
259
PsiMod Name
N6-lipoyl-L-lysine [MOD:00127]
PsiMod Definition
A protein modification that effectively converts an L-lysine residue to N6-lipoyl-L-lysine.
Cross References
RefSeq
OpenTargets
GeneCards
PRO
Orphanet
HMDB Protein
PDB