Phosphorylation of proteins involved in G2/M transition by active Cyclin A1:Cdc2 complexes

Stable Identifier
R-HSA-69754
Type
Reaction [transition]
Species
Homo sapiens
Compartment
nucleoplasm
ReviewStatus
5/5
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Phosphorylation of proteins involved in G2/M transition by active Cyclin A1:Cdc2 complexes
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At the beginning of this reaction, 1 molecule of 'ATP', and 1 molecule of 'G2/M transition protein' are present. At the end of this reaction, 1 molecule of 'ADP', and 1 molecule of 'phospho-G2/M transition protein' are present.

This reaction takes place in the 'nucleoplasm' and is mediated by the 'cyclin-dependent protein kinase activity' of 'Cyclin A1:Cdc2' (Liu et al. 2000).

Literature References
PubMed ID Title Journal Year
10926775 A role for cyclin A1 in the activation of MPF and G2-M transition during meiosis of male germ cells in mice

Liu, D, Liao, C, Wolgemuth, DJ

Dev. Biol. 2000
Participants
Input
Output
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as an event of
Catalyst Activity

cyclin-dependent protein serine/threonine kinase activity of CCNA1:p-T161-CDK1 [nucleoplasm]

Physical Entity
CCNA1:p-T161-CDK1 [nucleoplasm] (Homo sapiens)
Activity
cyclin-dependent protein serine/threonine kinase activity (GO:0004693)
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