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S Phase
Stable Identifier
R-HSA-69242
DOI
10.3180/REACT_899.2
Type
Pathway
Species
Homo sapiens
ReviewStatus
5/5
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Cell Cycle (Homo sapiens)
Cell Cycle, Mitotic (Homo sapiens)
S Phase (Homo sapiens)
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DNA synthesis occurs in the S phase, or the synthesis phase, of the cell cycle. The cell duplicates its hereditary material, and two copies of the chromosome are formed. As DNA replication continues, the E type cyclins shared by the G1 and S phases, are destroyed and the levels of the mitotic cyclins rise.
Participants
Events
Cyclin A:Cdk2-associated events at S phase entry
(Homo sapiens)
Synthesis of DNA
(Homo sapiens)
Ubiquitin-dependent degradation of Cyclin D
(Homo sapiens)
Establishment of Sister Chromatid Cohesion
(Homo sapiens)
Participates
as an event of
Cell Cycle, Mitotic (Homo sapiens)
Orthologous Events
S Phase (Bos taurus)
S Phase (Caenorhabditis elegans)
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S Phase (Danio rerio)
S Phase (Dictyostelium discoideum)
S Phase (Drosophila melanogaster)
S Phase (Gallus gallus)
S Phase (Mus musculus)
S Phase (Plasmodium falciparum)
S Phase (Rattus norvegicus)
S Phase (Saccharomyces cerevisiae)
S Phase (Schizosaccharomyces pombe)
S Phase (Sus scrofa)
S Phase (Xenopus tropicalis)
Reviewed
Manfredi, JJ (2018-07-10)
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