DNA polymerase epsilon binds at the origin

Stable Identifier
R-HSA-68960
Type
Reaction
Species
Homo sapiens
Compartment
nucleoplasm
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DNA polymerase epsilon binds at the origin
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At the beginning of this reaction, 1 molecule of 'origin of replication', and 1 molecule of 'DNA polymerase epsilon' are present. At the end of this reaction, 1 molecule of 'DNA polymerase epsilon:origin complex' is present.


Literature References
PubMed ID Title Journal Year
12045100 DNA replication in eukaryotic cells.

Bell, SP, Dutta, A

Annu Rev Biochem 2002
Participants
Input
Output
Participates
as an event of
This event is regulated
Positively by
Regulator
CDK:DDK:MCM10:active pre-replicative complex:CDC45:RPA1-4 [nucleoplasm] (Homo sapiens)
Orthologous Events
DNA polymerase epsilon binds at the origin (Bos taurus)
DNA polymerase epsilon binds at the origin (Caenorhabditis elegans)
DNA polymerase epsilon binds at the origin (Canis familiaris)
DNA polymerase epsilon binds at the origin (Danio rerio)
DNA polymerase epsilon binds at the origin (Dictyostelium discoideum)
DNA polymerase epsilon binds at the origin (Drosophila melanogaster)
DNA polymerase epsilon binds at the origin (Gallus gallus)
DNA polymerase epsilon binds at the origin (Mus musculus)
DNA polymerase epsilon binds at the origin (Plasmodium falciparum)
DNA polymerase epsilon binds at the origin (Rattus norvegicus)
DNA polymerase epsilon binds at the origin (Saccharomyces cerevisiae)
DNA polymerase epsilon binds at the origin (Schizosaccharomyces pombe)
DNA polymerase epsilon binds at the origin (Sus scrofa)
Created
O'Donnell, M  (2003-06-05)
Davey, MJ  (2003-06-05)
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