Ubiquitinated ORC1 is degraded by the proteasome in the cytosol (Li and DePamphilis 2002, Mendez et al. 2002).
Hidaka, M, Tansey, WP, Zou-Yang, XH, Mendez, J, Stillman, B, Kim, SY
DePamphilis, ML, Li, CJ
endopeptidase activity of 26S proteasome [cytosol]
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