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Cdt1 is displaced from the pre-replicative complex.
Stable Identifier
R-HSA-68940
Type
Reaction [dissociation]
Species
Homo sapiens
Compartment
nucleoplasm
ReviewStatus
5/5
Locations in the PathwayBrowser
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Cell Cycle (Homo sapiens)
Cell Cycle, Mitotic (Homo sapiens)
Mitotic G1 phase and G1/S transition (Homo sapiens)
G1/S Transition (Homo sapiens)
Activation of the pre-replicative complex (Homo sapiens)
Cdt1 is displaced from the pre-replicative complex. (Homo sapiens)
DNA Replication (Homo sapiens)
DNA Replication Pre-Initiation (Homo sapiens)
Activation of the pre-replicative complex (Homo sapiens)
Cdt1 is displaced from the pre-replicative complex. (Homo sapiens)
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The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
At the beginning of this reaction, 1 molecule of 'Mcm10:pre-replicative complex' is present. At the end of this reaction, 1 molecule of 'Mcm10:active pre-replicative complex', and 1 molecule of 'CDT1' are present.
This reaction takes place in the 'nucleus'.
Literature References
PubMed ID
Title
Journal
Year
12045100
DNA replication in eukaryotic cells.
Bell, SP
,
Dutta, A
Annu Rev Biochem
2002
Participants
Input
MCM10:pre-replicative complex [nucleoplasm]
(Homo sapiens)
Output
CDT1 [nucleoplasm]
(Homo sapiens)
MCM10:active pre-replicative complex [nucleoplasm]
(Homo sapiens)
Participates
as an event of
Activation of the pre-replicative complex (Homo sapiens)
Orthologous Events
Cdt1 is displaced from the pre-replicative complex. (Bos taurus)
Cdt1 is displaced from the pre-replicative complex. (Caenorhabditis elegans)
Cdt1 is displaced from the pre-replicative complex. (Canis familiaris)
Cdt1 is displaced from the pre-replicative complex. (Drosophila melanogaster)
Cdt1 is displaced from the pre-replicative complex. (Gallus gallus)
Cdt1 is displaced from the pre-replicative complex. (Mus musculus)
Cdt1 is displaced from the pre-replicative complex. (Rattus norvegicus)
Cdt1 is displaced from the pre-replicative complex. (Schizosaccharomyces pombe)
Cdt1 is displaced from the pre-replicative complex. (Sus scrofa)
Cdt1 is displaced from the pre-replicative complex. (Xenopus tropicalis)
Created
O'Donnell, M (2003-06-05)
Davey, MJ (2003-06-05)
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