Reactome | Orc3 associates with Orc2 constitutively bound at origins of replication

Orc3 associates with Orc2 constitutively bound at origins of replication

Stable Identifier

R-HSA-68595

Type

Reaction [binding]

Species

Homo sapiens

Compartment

nucleoplasm

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Orc3 associates with Orc2 constitutively bound at origins of replication

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The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout

At the beginning of this reaction, 1 molecule of 'Orc2:origin', and 1 molecule of 'Orc3' are present. At the end of this reaction, 1 molecule of 'Orc3:Orc2:origin' is present.

This reaction takes place in the 'nucleus'.

Literature References

PubMed ID	Title	Journal	Year
11046155	Chromatin association of human origin recognition complex, cdc6, and minichromosome maintenance proteins during the cell cycle: assembly of prereplication complexes in late mitosis. Mendez, J, Stillman, B	Mol Cell Biol	2000
11323433	Assembly of the human origin recognition complex. Vashee, S, Simancek, P, Challberg, MD, Kelly, TJ	J Biol Chem	2001
11395502	Architecture of the human origin recognition complex. Dhar, SK, Delmolino, L, Dutta, A	J Biol Chem	2001
9733749	Human minichromosome maintenance proteins and human origin recognition complex 2 protein on chromatin. Ritzi, M, Baack, M, Musahl, C, Romanowski, P, Laskey, RA, Knippers, R	J Biol Chem	1998