Orc3 associates with Orc2 constitutively bound at origins of replication

Stable Identifier
R-HSA-68595
Type
Reaction [binding]
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
General
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At the beginning of this reaction, 1 molecule of 'Orc2:origin', and 1 molecule of 'Orc3' are present. At the end of this reaction, 1 molecule of 'Orc3:Orc2:origin' is present.

This reaction takes place in the 'nucleus'.

Literature References
PubMed ID Title Journal Year
11046155 Chromatin association of human origin recognition complex, cdc6, and minichromosome maintenance proteins during the cell cycle: assembly of prereplication complexes in late mitosis.

Mendez, J, Stillman, B

Mol Cell Biol 2000
11323433 Assembly of the human origin recognition complex.

Vashee, S, Simancek, P, Challberg, MD, Kelly, TJ

J Biol Chem 2001
11395502 Architecture of the human origin recognition complex.

Dhar, SK, Delmolino, L, Dutta, A

J Biol Chem 2001
9733749 Human minichromosome maintenance proteins and human origin recognition complex 2 protein on chromatin.

Ritzi, M, Baack, M, Musahl, C, Romanowski, P, Laskey, RA, Knippers, R

J Biol Chem 1998
Participants
Participant Of
Orthologous Events
Created