Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
PRIM2 [nucleoplasm]
Stable Identifier
R-HSA-68495
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
p58, DNA primase large subunit , DNA primase 58 kDa subunit
Locations in the PathwayBrowser
Expand all
Cell Cycle (Homo sapiens)
Cell Cycle, Mitotic (Homo sapiens)
Mitotic G1 phase and G1/S transition (Homo sapiens)
G1/S Transition (Homo sapiens)
Activation of the pre-replicative complex (Homo sapiens)
DNA polymerase alpha:primase binds at the origin (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
PRIM2 [nucleoplasm] (Homo sapiens)
DNA polymerase alpha:primase:DNA polymerase alpha:origin complex [nucleoplasm] (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
PRIM2 [nucleoplasm] (Homo sapiens)
E2F mediated regulation of DNA replication (Homo sapiens)
Inhibition of replication initiation of damaged DNA by RB1/E2F1 (Homo sapiens)
Detection of damage during initiation of DNA synthesis in S-phase (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
PRIM2 [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
PRIM2 [nucleoplasm] (Homo sapiens)
S Phase (Homo sapiens)
Synthesis of DNA (Homo sapiens)
DNA replication initiation (Homo sapiens)
The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer at the origin (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
PRIM2 [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
PRIM2 [nucleoplasm] (Homo sapiens)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
PRIM2 [nucleoplasm] (Homo sapiens)
The primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer at the origin (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
PRIM2 [nucleoplasm] (Homo sapiens)
DNA polymerase alpha:primase:DNA polymerase alpha:origin complex [nucleoplasm] (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
PRIM2 [nucleoplasm] (Homo sapiens)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
PRIM2 [nucleoplasm] (Homo sapiens)
DNA strand elongation (Homo sapiens)
Lagging Strand Synthesis (Homo sapiens)
Polymerase switching (Homo sapiens)
Formation of Processive Complex (Homo sapiens)
Processive complex [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
PRIM2 [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
PRIM2 [nucleoplasm] (Homo sapiens)
Loading of PCNA - Sliding Clamp Formation (Homo sapiens)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
PRIM2 [nucleoplasm] (Homo sapiens)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex:PCNA homotrimer [nucleoplasm] (Homo sapiens)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
PRIM2 [nucleoplasm] (Homo sapiens)
RFC binding displaces Pol Alpha (Homo sapiens)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
PRIM2 [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
PRIM2 [nucleoplasm] (Homo sapiens)
RFC dissociates after sliding clamp formation (Homo sapiens)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex:PCNA homotrimer [nucleoplasm] (Homo sapiens)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
PRIM2 [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
PRIM2 [nucleoplasm] (Homo sapiens)
Processive synthesis on the lagging strand (Homo sapiens)
Formation of Okazaki fragments (Homo sapiens)
Processive complex [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
PRIM2 [nucleoplasm] (Homo sapiens)
Processive complex:Okazaki fragment complex [nucleoplasm] (Homo sapiens)
Processive complex [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
PRIM2 [nucleoplasm] (Homo sapiens)
Formation of the Flap Intermediate (Homo sapiens)
Processive complex:Okazaki fragment complex [nucleoplasm] (Homo sapiens)
Processive complex [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
PRIM2 [nucleoplasm] (Homo sapiens)
Processive complex:Okazaki fragment:Flap [nucleoplasm] (Homo sapiens)
Processive complex:Okazaki fragment complex [nucleoplasm] (Homo sapiens)
Processive complex [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
PRIM2 [nucleoplasm] (Homo sapiens)
Removal of the Flap Intermediate (Homo sapiens)
RPA binds to the Flap (Homo sapiens)
Processive complex:Okazaki fragment:Flap [nucleoplasm] (Homo sapiens)
Processive complex:Okazaki fragment complex [nucleoplasm] (Homo sapiens)
Processive complex [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
PRIM2 [nucleoplasm] (Homo sapiens)
Processive complex:Okazaki fragment:Flap:RPA heterotrimer [nucleoplasm] (Homo sapiens)
Processive complex:Okazaki fragment:Flap [nucleoplasm] (Homo sapiens)
Processive complex:Okazaki fragment complex [nucleoplasm] (Homo sapiens)
Processive complex [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
PRIM2 [nucleoplasm] (Homo sapiens)
Recruitment of Dna2 endonuclease (Homo sapiens)
Processive complex:Okazaki fragment:Flap:RPA heterotrimer [nucleoplasm] (Homo sapiens)
Processive complex:Okazaki fragment:Flap [nucleoplasm] (Homo sapiens)
Processive complex:Okazaki fragment complex [nucleoplasm] (Homo sapiens)
Processive complex [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
PRIM2 [nucleoplasm] (Homo sapiens)
Processive complex:Okazaki fragment:Flap:RPA heterotrimer:dna2 [nucleoplasm] (Homo sapiens)
Processive complex:Okazaki fragment:Flap:RPA heterotrimer [nucleoplasm] (Homo sapiens)
Processive complex:Okazaki fragment:Flap [nucleoplasm] (Homo sapiens)
Processive complex:Okazaki fragment complex [nucleoplasm] (Homo sapiens)
Processive complex [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
PRIM2 [nucleoplasm] (Homo sapiens)
Removal of RNA primer and dissociation of RPA and Dna2 (Homo sapiens)
Processive complex:Okazaki fragment:Flap:RPA heterotrimer:dna2 [nucleoplasm] (Homo sapiens)
Processive complex:Okazaki fragment:Flap:RPA heterotrimer [nucleoplasm] (Homo sapiens)
Processive complex:Okazaki fragment:Flap [nucleoplasm] (Homo sapiens)
Processive complex:Okazaki fragment complex [nucleoplasm] (Homo sapiens)
Processive complex [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
PRIM2 [nucleoplasm] (Homo sapiens)
Processive complex:Okazaki fragments:Remaining Flap [nucleoplasm] (Homo sapiens)
Processive complex [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
PRIM2 [nucleoplasm] (Homo sapiens)
Removal of remaining Flap (Homo sapiens)
Processive complex:Okazaki fragments:Remaining Flap [nucleoplasm] (Homo sapiens)
Processive complex [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
PRIM2 [nucleoplasm] (Homo sapiens)
Processive complex:nicked DNA from adjacent Okazaki fragments [nucleoplasm] (Homo sapiens)
Processive complex [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
PRIM2 [nucleoplasm] (Homo sapiens)
Leading Strand Synthesis (Homo sapiens)
Polymerase switching (Homo sapiens)
Formation of Processive Complex (Homo sapiens)
Processive complex [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
PRIM2 [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
PRIM2 [nucleoplasm] (Homo sapiens)
Loading of PCNA - Sliding Clamp Formation (Homo sapiens)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
PRIM2 [nucleoplasm] (Homo sapiens)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex:PCNA homotrimer [nucleoplasm] (Homo sapiens)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
PRIM2 [nucleoplasm] (Homo sapiens)
RFC binding displaces Pol Alpha (Homo sapiens)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
PRIM2 [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
PRIM2 [nucleoplasm] (Homo sapiens)
RFC dissociates after sliding clamp formation (Homo sapiens)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex:PCNA homotrimer [nucleoplasm] (Homo sapiens)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
PRIM2 [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
PRIM2 [nucleoplasm] (Homo sapiens)
Chromosome Maintenance (Homo sapiens)
Telomere Maintenance (Homo sapiens)
Extension of Telomeres (Homo sapiens)
Telomere C-strand (Lagging Strand) Synthesis (Homo sapiens)
Polymerase switching on the C-strand of the telomere (Homo sapiens)
RFC binding displaces Pol Alpha on the C-strand of the telomere (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
PRIM2 [nucleoplasm] (Homo sapiens)
RNA primer:DNA primer:G-strand extended telomere:POLA:primase [nucleoplasm] (Homo sapiens)
RNA primer:G-strand extended telomere end:POLA:primase [nucleoplasm] (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
PRIM2 [nucleoplasm] (Homo sapiens)
Telomere C-strand synthesis initiation (Homo sapiens)
DNA polymerase:primase binds G-strand of the telomere (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
PRIM2 [nucleoplasm] (Homo sapiens)
POLA:primase:G-strand extended telomere end [nucleoplasm] (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
PRIM2 [nucleoplasm] (Homo sapiens)
The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer on the G strand of the telomere (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
PRIM2 [nucleoplasm] (Homo sapiens)
RNA primer:DNA primer:G-strand extended telomere:POLA:primase [nucleoplasm] (Homo sapiens)
RNA primer:G-strand extended telomere end:POLA:primase [nucleoplasm] (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
PRIM2 [nucleoplasm] (Homo sapiens)
RNA primer:G-strand extended telomere end:POLA:primase [nucleoplasm] (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
PRIM2 [nucleoplasm] (Homo sapiens)
The primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer on the G strand of the telomere (Homo sapiens)
POLA:primase:G-strand extended telomere end [nucleoplasm] (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
PRIM2 [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
PRIM2 [nucleoplasm] (Homo sapiens)
RNA primer:G-strand extended telomere end:POLA:primase [nucleoplasm] (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
PRIM2 [nucleoplasm] (Homo sapiens)
DNA Replication (Homo sapiens)
DNA Replication Pre-Initiation (Homo sapiens)
Activation of the pre-replicative complex (Homo sapiens)
DNA polymerase alpha:primase binds at the origin (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
PRIM2 [nucleoplasm] (Homo sapiens)
DNA polymerase alpha:primase:DNA polymerase alpha:origin complex [nucleoplasm] (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
PRIM2 [nucleoplasm] (Homo sapiens)
Synthesis of DNA (Homo sapiens)
DNA replication initiation (Homo sapiens)
The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer at the origin (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
PRIM2 [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
PRIM2 [nucleoplasm] (Homo sapiens)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
PRIM2 [nucleoplasm] (Homo sapiens)
The primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer at the origin (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
PRIM2 [nucleoplasm] (Homo sapiens)
DNA polymerase alpha:primase:DNA polymerase alpha:origin complex [nucleoplasm] (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
PRIM2 [nucleoplasm] (Homo sapiens)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
PRIM2 [nucleoplasm] (Homo sapiens)
DNA strand elongation (Homo sapiens)
Lagging Strand Synthesis (Homo sapiens)
Polymerase switching (Homo sapiens)
Formation of Processive Complex (Homo sapiens)
Processive complex [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
PRIM2 [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
PRIM2 [nucleoplasm] (Homo sapiens)
Loading of PCNA - Sliding Clamp Formation (Homo sapiens)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
PRIM2 [nucleoplasm] (Homo sapiens)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex:PCNA homotrimer [nucleoplasm] (Homo sapiens)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
PRIM2 [nucleoplasm] (Homo sapiens)
RFC binding displaces Pol Alpha (Homo sapiens)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
PRIM2 [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
PRIM2 [nucleoplasm] (Homo sapiens)
RFC dissociates after sliding clamp formation (Homo sapiens)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex:PCNA homotrimer [nucleoplasm] (Homo sapiens)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
PRIM2 [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
PRIM2 [nucleoplasm] (Homo sapiens)
Processive synthesis on the lagging strand (Homo sapiens)
Formation of Okazaki fragments (Homo sapiens)
Processive complex [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
PRIM2 [nucleoplasm] (Homo sapiens)
Processive complex:Okazaki fragment complex [nucleoplasm] (Homo sapiens)
Processive complex [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
PRIM2 [nucleoplasm] (Homo sapiens)
Formation of the Flap Intermediate (Homo sapiens)
Processive complex:Okazaki fragment complex [nucleoplasm] (Homo sapiens)
Processive complex [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
PRIM2 [nucleoplasm] (Homo sapiens)
Processive complex:Okazaki fragment:Flap [nucleoplasm] (Homo sapiens)
Processive complex:Okazaki fragment complex [nucleoplasm] (Homo sapiens)
Processive complex [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
PRIM2 [nucleoplasm] (Homo sapiens)
Removal of the Flap Intermediate (Homo sapiens)
RPA binds to the Flap (Homo sapiens)
Processive complex:Okazaki fragment:Flap [nucleoplasm] (Homo sapiens)
Processive complex:Okazaki fragment complex [nucleoplasm] (Homo sapiens)
Processive complex [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
PRIM2 [nucleoplasm] (Homo sapiens)
Processive complex:Okazaki fragment:Flap:RPA heterotrimer [nucleoplasm] (Homo sapiens)
Processive complex:Okazaki fragment:Flap [nucleoplasm] (Homo sapiens)
Processive complex:Okazaki fragment complex [nucleoplasm] (Homo sapiens)
Processive complex [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
PRIM2 [nucleoplasm] (Homo sapiens)
Recruitment of Dna2 endonuclease (Homo sapiens)
Processive complex:Okazaki fragment:Flap:RPA heterotrimer [nucleoplasm] (Homo sapiens)
Processive complex:Okazaki fragment:Flap [nucleoplasm] (Homo sapiens)
Processive complex:Okazaki fragment complex [nucleoplasm] (Homo sapiens)
Processive complex [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
PRIM2 [nucleoplasm] (Homo sapiens)
Processive complex:Okazaki fragment:Flap:RPA heterotrimer:dna2 [nucleoplasm] (Homo sapiens)
Processive complex:Okazaki fragment:Flap:RPA heterotrimer [nucleoplasm] (Homo sapiens)
Processive complex:Okazaki fragment:Flap [nucleoplasm] (Homo sapiens)
Processive complex:Okazaki fragment complex [nucleoplasm] (Homo sapiens)
Processive complex [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
PRIM2 [nucleoplasm] (Homo sapiens)
Removal of RNA primer and dissociation of RPA and Dna2 (Homo sapiens)
Processive complex:Okazaki fragment:Flap:RPA heterotrimer:dna2 [nucleoplasm] (Homo sapiens)
Processive complex:Okazaki fragment:Flap:RPA heterotrimer [nucleoplasm] (Homo sapiens)
Processive complex:Okazaki fragment:Flap [nucleoplasm] (Homo sapiens)
Processive complex:Okazaki fragment complex [nucleoplasm] (Homo sapiens)
Processive complex [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
PRIM2 [nucleoplasm] (Homo sapiens)
Processive complex:Okazaki fragments:Remaining Flap [nucleoplasm] (Homo sapiens)
Processive complex [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
PRIM2 [nucleoplasm] (Homo sapiens)
Removal of remaining Flap (Homo sapiens)
Processive complex:Okazaki fragments:Remaining Flap [nucleoplasm] (Homo sapiens)
Processive complex [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
PRIM2 [nucleoplasm] (Homo sapiens)
Processive complex:nicked DNA from adjacent Okazaki fragments [nucleoplasm] (Homo sapiens)
Processive complex [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
PRIM2 [nucleoplasm] (Homo sapiens)
Leading Strand Synthesis (Homo sapiens)
Polymerase switching (Homo sapiens)
Formation of Processive Complex (Homo sapiens)
Processive complex [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
PRIM2 [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
PRIM2 [nucleoplasm] (Homo sapiens)
Loading of PCNA - Sliding Clamp Formation (Homo sapiens)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
PRIM2 [nucleoplasm] (Homo sapiens)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex:PCNA homotrimer [nucleoplasm] (Homo sapiens)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
PRIM2 [nucleoplasm] (Homo sapiens)
RFC binding displaces Pol Alpha (Homo sapiens)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
PRIM2 [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
PRIM2 [nucleoplasm] (Homo sapiens)
RFC dissociates after sliding clamp formation (Homo sapiens)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex:PCNA homotrimer [nucleoplasm] (Homo sapiens)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
PRIM2 [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
PRIM2 [nucleoplasm] (Homo sapiens)
Disease (Homo sapiens)
Diseases of programmed cell death (Homo sapiens)
Defective pyroptosis (Homo sapiens)
Decitabine triphosphate incorporates into DNA (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
PRIM2 [nucleoplasm] (Homo sapiens)
RNA primer:decitabine-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
PRIM2 [nucleoplasm] (Homo sapiens)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
PRIM2 [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:P49643 PRIM2
Gene Names
PRIM2, PRIM2A
Chain
chain:1-509
Reference Genes
BioGPS Gene:5558 PRIM2
COSMIC (genes):PRIM2 PRIM2
CTD Gene:5558 PRIM2
dbSNP Gene:5558 PRIM2
ENSEMBL:ENSG00000146143 PRIM2
HGNC:9370 PRIM2
KEGG:hsa:5558 PRIM2
Monarch:5558 PRIM2
NCBI Gene:5558 PRIM2
OMIM:176636 PRIM2
UCSC:P49643 PRIM2
Reference Transcript
RefSeq:NM_001282488.2 PRIM2
RefSeq:NM_001282487.2 PRIM2
RefSeq:XM_054355808.1 PRIM2
RefSeq:NM_000947.4 PRIM2
RefSeq:XM_047418987.1 PRIM2
Other Identifiers
11725687_s_at
11750054_a_at
122_at
1554884_PM_at
1554884_at
1554885_PM_a_at
1554885_a_at
17009862
205628_PM_at
205628_at
215708_PM_s_at
215708_s_at
215709_PM_at
215709_at
2911422
2911425
2911426
2911428
2911429
2911430
2911431
2911432
2911433
2911434
2911441
2911443
2911444
2911445
2911446
2911448
2911454
2911455
2911456
2911458
2911459
2911461
2911462
2911468
2911473
36898_r_at
42358_at
5558
8120411
A_14_P101006
A_14_P104636
A_14_P120020
A_23_P44139
A_24_P282237
GE59992
GO:0003677
GO:0005515
GO:0005654
GO:0005658
GO:0006260
GO:0006261
GO:0006269
GO:0006270
GO:0046872
GO:0051539
GO:0071667
HMNXSV003001650
HMNXSV003017568
HMNXSV003018201
HMNXSV003042514
Hs.74519.1.S1_3p_at
Hs2.74519.2.S1_3p_at
ILMN_1694100
ILMN_1742922
ILMN_1775975
PH_hs_0028461
TC06000685.hg
X74331_at
g4506052_3p_at
p14571
p14573
p14574
p33572
Participates
as a component of
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
Inferred To
Prim2 [nucleoplasm]
(Drosophila melanogaster)
Prim2 [nucleoplasm]
(Mus musculus)
Prim2 [nucleoplasm]
(Rattus norvegicus)
PRI2 [nucleoplasm]
(Saccharomyces cerevisiae)
PRIM2 [nucleoplasm]
(Bos taurus)
PRIM2 [nucleoplasm]
(Canis familiaris)
PRIM2 [nucleoplasm]
(Gallus gallus)
PRIM2 [nucleoplasm]
(Plasmodium falciparum)
PRIM2 [nucleoplasm]
(Sus scrofa)
prim2 [nucleoplasm]
(Dictyostelium discoideum)
spp2 [nucleoplasm]
(Schizosaccharomyces pombe)
pri-2 [nucleoplasm]
(Caenorhabditis elegans)
Cross References
RefSeq
XP_047274943.1
,
NP_001269416.1
,
NP_000938.2
,
XP_054211783.1
,
NP_001269417.1
OpenTargets
ENSG00000146143
ENSEMBL
ENSP00000483201
,
ENST00000615550
,
ENST00000370687
,
ENSG00000146143
,
ENSP00000484105
,
ENSP00000485304
,
ENST00000274891
HPA
ENSG00000146143-PRIM2
GeneCards
PRIM2
PRO
P49643
Pharos - Targets
P49643
GlyGen
P49643
PDB
4BPX
,
6DHW
,
5DQO
,
5F0S
,
4BPW
,
7U5C
,
8D0K
,
4BPU
,
5I7M
,
5F0Q
,
5EXR
,
3L9Q
,
3Q36
,
9C8V
,
8D0B
,
8QJ7
,
8D96
,
8VY3
,
7OPL
,
8D9D
,
4RR2
,
8B9D
HMDB Protein
HMDBP11900
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q13257 MAD2L1
2
MAD2L1 [cytosol]
(R-HSA-141400)
Activated MAD2L1 [cytosol]
(R-HSA-141447)
0.527
2
© 2025
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text
