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CCNE2 [nucleoplasm]
Stable Identifier
R-HSA-68367
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
G1/S-Specific cyclin E2
Locations in the PathwayBrowser
Expand all
Cell Cycle (Homo sapiens)
Cell Cycle Checkpoints (Homo sapiens)
G1/S DNA Damage Checkpoints (Homo sapiens)
p53-Dependent G1/S DNA damage checkpoint (Homo sapiens)
p53-Dependent G1 DNA Damage Response (Homo sapiens)
Inactivation of Cyclin E:Cdk2 complexes by p27/p21 (Homo sapiens)
CCNE:CDK2 [nucleoplasm] (Homo sapiens)
Cyclin E [nucleoplasm] (Homo sapiens)
CCNE2 [nucleoplasm] (Homo sapiens)
Cyclin E:CDK2:CDKN1A,CDKN1B [nucleoplasm] (Homo sapiens)
CCNE:CDK2 [nucleoplasm] (Homo sapiens)
Cyclin E [nucleoplasm] (Homo sapiens)
CCNE2 [nucleoplasm] (Homo sapiens)
Cell Cycle, Mitotic (Homo sapiens)
Mitotic G1 phase and G1/S transition (Homo sapiens)
G0 and Early G1 (Homo sapiens)
p107 (RBL1) binds CyclinE/A:CDK2 (Homo sapiens)
Cyclin E/A:CDK2 [nucleoplasm] (Homo sapiens)
Cyclin E/A [nucleoplasm] (Homo sapiens)
Cyclin E [nucleoplasm] (Homo sapiens)
CCNE2 [nucleoplasm] (Homo sapiens)
RBL1:Cyclin E/A:CDK2 [nucleoplasm] (Homo sapiens)
Cyclin E/A:CDK2 [nucleoplasm] (Homo sapiens)
Cyclin E/A [nucleoplasm] (Homo sapiens)
Cyclin E [nucleoplasm] (Homo sapiens)
CCNE2 [nucleoplasm] (Homo sapiens)
p107 (RBL1) in complex with E2F4:DP1/2 binds to cyclin E/A:CDK2 (Homo sapiens)
Cyclin E/A:CDK2 [nucleoplasm] (Homo sapiens)
Cyclin E/A [nucleoplasm] (Homo sapiens)
Cyclin E [nucleoplasm] (Homo sapiens)
CCNE2 [nucleoplasm] (Homo sapiens)
RBL1:E2F4:DP1/2:Cyclin E/A:CDK2 [nucleoplasm] (Homo sapiens)
Cyclin E/A:CDK2 [nucleoplasm] (Homo sapiens)
Cyclin E/A [nucleoplasm] (Homo sapiens)
Cyclin E [nucleoplasm] (Homo sapiens)
CCNE2 [nucleoplasm] (Homo sapiens)
p130 (RBL2) binds Cyclin E/A:CDK2 (Homo sapiens)
Cyclin E/A:CDK2 [nucleoplasm] (Homo sapiens)
Cyclin E/A [nucleoplasm] (Homo sapiens)
Cyclin E [nucleoplasm] (Homo sapiens)
CCNE2 [nucleoplasm] (Homo sapiens)
RBL2:Cyclin E/A:CDK2 [nucleoplasm] (Homo sapiens)
Cyclin E/A:CDK2 [nucleoplasm] (Homo sapiens)
Cyclin E/A [nucleoplasm] (Homo sapiens)
Cyclin E [nucleoplasm] (Homo sapiens)
CCNE2 [nucleoplasm] (Homo sapiens)
p130 (RBL2) in complex with E2F4/5:DP1/2 binds to cyclin E/A:CDK2 (Homo sapiens)
Cyclin E/A:CDK2 [nucleoplasm] (Homo sapiens)
Cyclin E/A [nucleoplasm] (Homo sapiens)
Cyclin E [nucleoplasm] (Homo sapiens)
CCNE2 [nucleoplasm] (Homo sapiens)
RBL2:E2F4/5:DP1/2:Cyclin E/A:CDK2 [nucleoplasm] (Homo sapiens)
Cyclin E/A:CDK2 [nucleoplasm] (Homo sapiens)
Cyclin E/A [nucleoplasm] (Homo sapiens)
Cyclin E [nucleoplasm] (Homo sapiens)
CCNE2 [nucleoplasm] (Homo sapiens)
G1 Phase (Homo sapiens)
Cyclin D associated events in G1 (Homo sapiens)
RB1 binds and inhibits E2F1/2/3:DP1/2 complexes (Homo sapiens)
Cyclin E:p-T160-CDK2 [nucleoplasm] (Homo sapiens)
Cyclin E [nucleoplasm] (Homo sapiens)
CCNE2 [nucleoplasm] (Homo sapiens)
G1/S Transition (Homo sapiens)
Cyclin E associated events during G1/S transition (Homo sapiens)
Association of Rb with Cyclin E:Cdk2 complexes (Homo sapiens)
CCNE:p-T160-CDK2:hypophosphorylated RB1 [nucleoplasm] (Homo sapiens)
Cyclin E:p-T160-CDK2 [nucleoplasm] (Homo sapiens)
Cyclin E [nucleoplasm] (Homo sapiens)
CCNE2 [nucleoplasm] (Homo sapiens)
Cyclin E:p-T160-CDK2 [nucleoplasm] (Homo sapiens)
Cyclin E [nucleoplasm] (Homo sapiens)
CCNE2 [nucleoplasm] (Homo sapiens)
CAK-mediated phosphorylation of Cyclin E:Cdk2 (Homo sapiens)
CCNE:CDK2 [nucleoplasm] (Homo sapiens)
Cyclin E [nucleoplasm] (Homo sapiens)
CCNE2 [nucleoplasm] (Homo sapiens)
Cyclin E:p-T160-CDK2 [nucleoplasm] (Homo sapiens)
Cyclin E [nucleoplasm] (Homo sapiens)
CCNE2 [nucleoplasm] (Homo sapiens)
Dephosphorylation of Cyclin E:Cdk2 complexes by Cdc25A (Homo sapiens)
CCNE:CDK2 [nucleoplasm] (Homo sapiens)
Cyclin E [nucleoplasm] (Homo sapiens)
CCNE2 [nucleoplasm] (Homo sapiens)
Cyclin E:p-CDK2 [nucleoplasm] (Homo sapiens)
Cyclin E [nucleoplasm] (Homo sapiens)
CCNE2 [nucleoplasm] (Homo sapiens)
Inactivation of Cyclin E:Cdk2 complexes by p27/p21 (Homo sapiens)
CCNE:CDK2 [nucleoplasm] (Homo sapiens)
Cyclin E [nucleoplasm] (Homo sapiens)
CCNE2 [nucleoplasm] (Homo sapiens)
Cyclin E:CDK2:CDKN1A,CDKN1B [nucleoplasm] (Homo sapiens)
CCNE:CDK2 [nucleoplasm] (Homo sapiens)
Cyclin E [nucleoplasm] (Homo sapiens)
CCNE2 [nucleoplasm] (Homo sapiens)
Phosphorylation of Cyclin E:CDK2 complexes by WEE1 (Homo sapiens)
CCNE:CDK2 [nucleoplasm] (Homo sapiens)
Cyclin E [nucleoplasm] (Homo sapiens)
CCNE2 [nucleoplasm] (Homo sapiens)
Cyclin E:p-CDK2 [nucleoplasm] (Homo sapiens)
Cyclin E [nucleoplasm] (Homo sapiens)
CCNE2 [nucleoplasm] (Homo sapiens)
Phosphorylation of proteins involved in G1/S transition by active Cyclin E:Cdk2 complexes (Homo sapiens)
Cyclin E:CDK2-mediated phosphorylation of RB1 (Homo sapiens)
CCNE:p-T160-CDK2:hypophosphorylated RB1 [nucleoplasm] (Homo sapiens)
Cyclin E:p-T160-CDK2 [nucleoplasm] (Homo sapiens)
Cyclin E [nucleoplasm] (Homo sapiens)
CCNE2 [nucleoplasm] (Homo sapiens)
Cyclin E:p-T160-CDK2 [nucleoplasm] (Homo sapiens)
Cyclin E [nucleoplasm] (Homo sapiens)
CCNE2 [nucleoplasm] (Homo sapiens)
SCF(Skp2)-mediated degradation of p27/p21 (Homo sapiens)
Binding of phospho-p27/p21:Cdk2:Cyclin E/A to the SCF(Skp2):Cks1 complex (Homo sapiens)
Cyclin E/A:CDK2:p-S130-CDKN1A,p-T187-CDKN1B:CUL1:SKP1:SKP2:CKS1B [nucleoplasm] (Homo sapiens)
Cyclin E/A:p-T160-CDK2:p-S130-CDKN1A,p-T187-CDKN1B [nucleoplasm] (Homo sapiens)
CCNA:p-T160-CDK2,CCNE:p-T160-CDK2 [nucleoplasm] (Homo sapiens)
Cyclin E:p-T160-CDK2 [nucleoplasm] (Homo sapiens)
Cyclin E [nucleoplasm] (Homo sapiens)
CCNE2 [nucleoplasm] (Homo sapiens)
Cyclin E/A:p-T160-CDK2:p-S130-CDKN1A,p-T187-CDKN1B [nucleoplasm] (Homo sapiens)
CCNA:p-T160-CDK2,CCNE:p-T160-CDK2 [nucleoplasm] (Homo sapiens)
Cyclin E:p-T160-CDK2 [nucleoplasm] (Homo sapiens)
Cyclin E [nucleoplasm] (Homo sapiens)
CCNE2 [nucleoplasm] (Homo sapiens)
Cyclin E/A:Cdk2-mediated phosphorylation of p27/p21 (Homo sapiens)
Cyclin E/A:p-T160-CDK2:CDKN1A,CDKN1B [nucleoplasm] (Homo sapiens)
CCNA:p-T160-CDK2,CCNE:p-T160-CDK2 [nucleoplasm] (Homo sapiens)
Cyclin E:p-T160-CDK2 [nucleoplasm] (Homo sapiens)
Cyclin E [nucleoplasm] (Homo sapiens)
CCNE2 [nucleoplasm] (Homo sapiens)
Cyclin E/A:p-T160-CDK2:p-S130-CDKN1A,p-T187-CDKN1B [nucleoplasm] (Homo sapiens)
CCNA:p-T160-CDK2,CCNE:p-T160-CDK2 [nucleoplasm] (Homo sapiens)
Cyclin E:p-T160-CDK2 [nucleoplasm] (Homo sapiens)
Cyclin E [nucleoplasm] (Homo sapiens)
CCNE2 [nucleoplasm] (Homo sapiens)
Degradation of ubiquitinated p27/p21 by the 26S proteasome (Homo sapiens)
CCNA:p-T160-CDK2,CCNE:p-T160-CDK2 [nucleoplasm] (Homo sapiens)
Cyclin E:p-T160-CDK2 [nucleoplasm] (Homo sapiens)
Cyclin E [nucleoplasm] (Homo sapiens)
CCNE2 [nucleoplasm] (Homo sapiens)
Cyclin E/A:CDK2:p-S130-CDKN1A,p-T187-CDKN1B:CUL1:SKP1:SKP2:CKS1B:3xubiquitin [nucleoplasm] (Homo sapiens)
Cyclin E/A:CDK2:p-S130-CDKN1A,p-T187-CDKN1B:CUL1:SKP1:SKP2:CKS1B [nucleoplasm] (Homo sapiens)
Cyclin E/A:p-T160-CDK2:p-S130-CDKN1A,p-T187-CDKN1B [nucleoplasm] (Homo sapiens)
CCNA:p-T160-CDK2,CCNE:p-T160-CDK2 [nucleoplasm] (Homo sapiens)
Cyclin E:p-T160-CDK2 [nucleoplasm] (Homo sapiens)
Cyclin E [nucleoplasm] (Homo sapiens)
CCNE2 [nucleoplasm] (Homo sapiens)
Ubiquitination of phospho-p27/p21 (Homo sapiens)
Cyclin E/A:CDK2:p-S130-CDKN1A,p-T187-CDKN1B:CUL1:SKP1:SKP2:CKS1B [nucleoplasm] (Homo sapiens)
Cyclin E/A:p-T160-CDK2:p-S130-CDKN1A,p-T187-CDKN1B [nucleoplasm] (Homo sapiens)
CCNA:p-T160-CDK2,CCNE:p-T160-CDK2 [nucleoplasm] (Homo sapiens)
Cyclin E:p-T160-CDK2 [nucleoplasm] (Homo sapiens)
Cyclin E [nucleoplasm] (Homo sapiens)
CCNE2 [nucleoplasm] (Homo sapiens)
Cyclin E/A:CDK2:p-S130-CDKN1A,p-T187-CDKN1B:CUL1:SKP1:SKP2:CKS1B:3xubiquitin [nucleoplasm] (Homo sapiens)
Cyclin E/A:CDK2:p-S130-CDKN1A,p-T187-CDKN1B:CUL1:SKP1:SKP2:CKS1B [nucleoplasm] (Homo sapiens)
Cyclin E/A:p-T160-CDK2:p-S130-CDKN1A,p-T187-CDKN1B [nucleoplasm] (Homo sapiens)
CCNA:p-T160-CDK2,CCNE:p-T160-CDK2 [nucleoplasm] (Homo sapiens)
Cyclin E:p-T160-CDK2 [nucleoplasm] (Homo sapiens)
Cyclin E [nucleoplasm] (Homo sapiens)
CCNE2 [nucleoplasm] (Homo sapiens)
Translocation of Cyclin E:Cdk2 complex to the nucleus (Homo sapiens)
CCNE:CDK2 [nucleoplasm] (Homo sapiens)
Cyclin E [nucleoplasm] (Homo sapiens)
CCNE2 [nucleoplasm] (Homo sapiens)
S Phase (Homo sapiens)
Cyclin A:Cdk2-associated events at S phase entry (Homo sapiens)
SCF(Skp2)-mediated degradation of p27/p21 (Homo sapiens)
Binding of phospho-p27/p21:Cdk2:Cyclin E/A to the SCF(Skp2):Cks1 complex (Homo sapiens)
Cyclin E/A:CDK2:p-S130-CDKN1A,p-T187-CDKN1B:CUL1:SKP1:SKP2:CKS1B [nucleoplasm] (Homo sapiens)
Cyclin E/A:p-T160-CDK2:p-S130-CDKN1A,p-T187-CDKN1B [nucleoplasm] (Homo sapiens)
CCNA:p-T160-CDK2,CCNE:p-T160-CDK2 [nucleoplasm] (Homo sapiens)
Cyclin E:p-T160-CDK2 [nucleoplasm] (Homo sapiens)
Cyclin E [nucleoplasm] (Homo sapiens)
CCNE2 [nucleoplasm] (Homo sapiens)
Cyclin E/A:p-T160-CDK2:p-S130-CDKN1A,p-T187-CDKN1B [nucleoplasm] (Homo sapiens)
CCNA:p-T160-CDK2,CCNE:p-T160-CDK2 [nucleoplasm] (Homo sapiens)
Cyclin E:p-T160-CDK2 [nucleoplasm] (Homo sapiens)
Cyclin E [nucleoplasm] (Homo sapiens)
CCNE2 [nucleoplasm] (Homo sapiens)
Cyclin E/A:Cdk2-mediated phosphorylation of p27/p21 (Homo sapiens)
Cyclin E/A:p-T160-CDK2:CDKN1A,CDKN1B [nucleoplasm] (Homo sapiens)
CCNA:p-T160-CDK2,CCNE:p-T160-CDK2 [nucleoplasm] (Homo sapiens)
Cyclin E:p-T160-CDK2 [nucleoplasm] (Homo sapiens)
Cyclin E [nucleoplasm] (Homo sapiens)
CCNE2 [nucleoplasm] (Homo sapiens)
Cyclin E/A:p-T160-CDK2:p-S130-CDKN1A,p-T187-CDKN1B [nucleoplasm] (Homo sapiens)
CCNA:p-T160-CDK2,CCNE:p-T160-CDK2 [nucleoplasm] (Homo sapiens)
Cyclin E:p-T160-CDK2 [nucleoplasm] (Homo sapiens)
Cyclin E [nucleoplasm] (Homo sapiens)
CCNE2 [nucleoplasm] (Homo sapiens)
Degradation of ubiquitinated p27/p21 by the 26S proteasome (Homo sapiens)
CCNA:p-T160-CDK2,CCNE:p-T160-CDK2 [nucleoplasm] (Homo sapiens)
Cyclin E:p-T160-CDK2 [nucleoplasm] (Homo sapiens)
Cyclin E [nucleoplasm] (Homo sapiens)
CCNE2 [nucleoplasm] (Homo sapiens)
Cyclin E/A:CDK2:p-S130-CDKN1A,p-T187-CDKN1B:CUL1:SKP1:SKP2:CKS1B:3xubiquitin [nucleoplasm] (Homo sapiens)
Cyclin E/A:CDK2:p-S130-CDKN1A,p-T187-CDKN1B:CUL1:SKP1:SKP2:CKS1B [nucleoplasm] (Homo sapiens)
Cyclin E/A:p-T160-CDK2:p-S130-CDKN1A,p-T187-CDKN1B [nucleoplasm] (Homo sapiens)
CCNA:p-T160-CDK2,CCNE:p-T160-CDK2 [nucleoplasm] (Homo sapiens)
Cyclin E:p-T160-CDK2 [nucleoplasm] (Homo sapiens)
Cyclin E [nucleoplasm] (Homo sapiens)
CCNE2 [nucleoplasm] (Homo sapiens)
Ubiquitination of phospho-p27/p21 (Homo sapiens)
Cyclin E/A:CDK2:p-S130-CDKN1A,p-T187-CDKN1B:CUL1:SKP1:SKP2:CKS1B [nucleoplasm] (Homo sapiens)
Cyclin E/A:p-T160-CDK2:p-S130-CDKN1A,p-T187-CDKN1B [nucleoplasm] (Homo sapiens)
CCNA:p-T160-CDK2,CCNE:p-T160-CDK2 [nucleoplasm] (Homo sapiens)
Cyclin E:p-T160-CDK2 [nucleoplasm] (Homo sapiens)
Cyclin E [nucleoplasm] (Homo sapiens)
CCNE2 [nucleoplasm] (Homo sapiens)
Cyclin E/A:CDK2:p-S130-CDKN1A,p-T187-CDKN1B:CUL1:SKP1:SKP2:CKS1B:3xubiquitin [nucleoplasm] (Homo sapiens)
Cyclin E/A:CDK2:p-S130-CDKN1A,p-T187-CDKN1B:CUL1:SKP1:SKP2:CKS1B [nucleoplasm] (Homo sapiens)
Cyclin E/A:p-T160-CDK2:p-S130-CDKN1A,p-T187-CDKN1B [nucleoplasm] (Homo sapiens)
CCNA:p-T160-CDK2,CCNE:p-T160-CDK2 [nucleoplasm] (Homo sapiens)
Cyclin E:p-T160-CDK2 [nucleoplasm] (Homo sapiens)
Cyclin E [nucleoplasm] (Homo sapiens)
CCNE2 [nucleoplasm] (Homo sapiens)
Synthesis of DNA (Homo sapiens)
Switching of origins to a post-replicative state (Homo sapiens)
CDK-mediated phosphorylation and removal of Cdc6 (Homo sapiens)
Cdc6 protein is phosphorylated by CDK (Homo sapiens)
CCNA:p-T160-CDK2,CCNE:p-T160-CDK2 [nucleoplasm] (Homo sapiens)
Cyclin E:p-T160-CDK2 [nucleoplasm] (Homo sapiens)
Cyclin E [nucleoplasm] (Homo sapiens)
CCNE2 [nucleoplasm] (Homo sapiens)
Cellular responses to stimuli (Homo sapiens)
Cellular responses to stress (Homo sapiens)
Cellular Senescence (Homo sapiens)
DNA Damage/Telomere Stress Induced Senescence (Homo sapiens)
Inactivation of Cyclin E:Cdk2 complexes by p27/p21 (Homo sapiens)
CCNE:CDK2 [nucleoplasm] (Homo sapiens)
Cyclin E [nucleoplasm] (Homo sapiens)
CCNE2 [nucleoplasm] (Homo sapiens)
Cyclin E:CDK2:CDKN1A,CDKN1B [nucleoplasm] (Homo sapiens)
CCNE:CDK2 [nucleoplasm] (Homo sapiens)
Cyclin E [nucleoplasm] (Homo sapiens)
CCNE2 [nucleoplasm] (Homo sapiens)
DNA Replication (Homo sapiens)
Synthesis of DNA (Homo sapiens)
Switching of origins to a post-replicative state (Homo sapiens)
CDK-mediated phosphorylation and removal of Cdc6 (Homo sapiens)
Cdc6 protein is phosphorylated by CDK (Homo sapiens)
CCNA:p-T160-CDK2,CCNE:p-T160-CDK2 [nucleoplasm] (Homo sapiens)
Cyclin E:p-T160-CDK2 [nucleoplasm] (Homo sapiens)
Cyclin E [nucleoplasm] (Homo sapiens)
CCNE2 [nucleoplasm] (Homo sapiens)
Disease (Homo sapiens)
Diseases of mitotic cell cycle (Homo sapiens)
Aberrant regulation of mitotic cell cycle due to RB1 defects (Homo sapiens)
Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects (Homo sapiens)
Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) (Homo sapiens)
Defective RB1 does not bind E2F1,(E2F2,E2F3) (Homo sapiens)
Cyclin E:p-T160-CDK2 [nucleoplasm] (Homo sapiens)
Cyclin E [nucleoplasm] (Homo sapiens)
CCNE2 [nucleoplasm] (Homo sapiens)
Gene expression (Transcription) (Homo sapiens)
RNA Polymerase II Transcription (Homo sapiens)
Generic Transcription Pathway (Homo sapiens)
Transcriptional Regulation by TP53 (Homo sapiens)
TP53 Regulates Transcription of Cell Cycle Genes (Homo sapiens)
TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest (Homo sapiens)
Inactivation of Cyclin E:Cdk2 complexes by p27/p21 (Homo sapiens)
CCNE:CDK2 [nucleoplasm] (Homo sapiens)
Cyclin E [nucleoplasm] (Homo sapiens)
CCNE2 [nucleoplasm] (Homo sapiens)
Cyclin E:CDK2:CDKN1A,CDKN1B [nucleoplasm] (Homo sapiens)
CCNE:CDK2 [nucleoplasm] (Homo sapiens)
Cyclin E [nucleoplasm] (Homo sapiens)
CCNE2 [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:O96020 CCNE2
Gene Names
CCNE2
Chain
chain:1-404
Reference Genes
BioGPS Gene:9134 CCNE2
COSMIC (genes):CCNE2 CCNE2
CTD Gene:9134 CCNE2
dbSNP Gene:9134 CCNE2
ENSEMBL:ENSG00000175305 CCNE2
ENSEMBL_homo_sapiens_GENE:ENSG00000175305.18 CCNE2
HGNC:1590 CCNE2
KEGG Gene (Homo sapiens):9134 CCNE2
Monarch:9134 CCNE2
NCBI Gene:9134 CCNE2
OMIM:603775 CCNE2
UCSC:O96020 CCNE2
Reference Transcript
RefSeq:NM_057749.2 CCNE2
RefSeq:XM_017013959.1 CCNE2
RefSeq:XM_017013957.1 CCNE2
RefSeq:XM_017013958.1 CCNE2
Other Identifiers
11728300_at
11728301_a_at
17079293
205034_PM_at
205034_at
211814_PM_s_at
211814_s_at
3145108
3145109
3145110
3145111
3145112
3145113
3145115
3145116
3145117
3145118
3145119
3145120
3145121
3145123
3145125
3145126
3145127
3145132
35249_at
8151871
82614_g_at
9134
A_23_P215976
A_33_P3217819
A_33_P3247022
GE54769
GO:0000079
GO:0000082
GO:0000278
GO:0000723
GO:0005515
GO:0005634
GO:0005654
GO:0005737
GO:0005813
GO:0005815
GO:0005829
GO:0005856
GO:0006260
GO:0006270
GO:0007049
GO:0007059
GO:0007129
GO:0016538
GO:0019901
GO:0022414
GO:0032200
GO:0032880
GO:0036211
GO:0043226
GO:0051301
GO:0051726
GO:0070192
GO:0097134
GO:0097135
GO:0098772
GO:0140013
HMNXSV003006841
ILMN_1651260
ILMN_2412384
PH_hs_0040024
TC08001438.hg
g4092787_3p_a_at
g4757931_3p_at
Participates
as a candidate of
Cyclin E [nucleoplasm] (Homo sapiens)
as a member of
Cyclin E [nucleoplasm] (Homo sapiens)
Other forms of this molecule
Unfolded CCNE2 [cytosol]
CCNE2 [cytosol]
Inferred To
CycE [nucleoplasm]
(Drosophila melanogaster)
Ccne2 [nucleoplasm]
(Mus musculus)
Ccne2 [nucleoplasm]
(Rattus norvegicus)
cye-1 [nucleoplasm]
(Caenorhabditis elegans)
CCNE2 [nucleoplasm]
(Bos taurus)
CCNE2 [nucleoplasm]
(Canis familiaris)
CCNE2 [nucleoplasm]
(Gallus gallus)
CCNE2 [nucleoplasm]
(Sus scrofa)
ccne2 [nucleoplasm]
(Danio rerio)
ccne2 [nucleoplasm]
(Xenopus tropicalis)
Cross References
RefSeq
XP_016869448.1
,
XP_016869446.1
,
XP_016869447.1
,
NP_477097.1
OpenTargets
ENSG00000175305
HPA
ENSG00000175305-CCNE2
GeneCards
O96020
Ensembl
ENSP00000429089
,
ENST00000308108
,
ENSP00000309181
,
ENST00000520509
,
ENSG00000175305
PRO
O96020
Pharos - Targets
O96020
PDB
8HN9
Interactors (8)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P24941 CDK2
5
p-Y15-CDK2 [nucleoplasm]
(R-HSA-187905)
p-CDK2 [nucleoplasm]
(R-HSA-68370)
CDK2 [cytosol]
(R-HSA-157440)
CDK2 [nucleoplasm]
(R-HSA-68365)
p-T160-CDK2 [nucleoplasm]
(R-HSA-187967)
0.937
15
UniProt:P38936 CDKN1A
5
p-T145-CDKN1A [cytosol]
(R-HSA-198614)
p-Y77-CDKN1A [cytosol]
(R-HSA-8942601)
CDKN1A [cytosol]
(R-HSA-182512)
CDKN1A [nucleoplasm]
(R-HSA-182585)
p-S130-CDKN1A [nucleoplasm]
(R-HSA-187857)
0.888
8
UniProt:P46527 CDKN1B
8
p-S10 CDKN1B [cytosol]
(R-HSA-9632829)
p-S10 CDKN1B [nucleoplasm]
(R-HSA-9632832)
p-T157-CDKN1B [cytosol]
(R-HSA-198629)
CDKN1B [cytosol]
(R-HSA-198622)
p-Y88-CDKN1B [cytosol]
(R-HSA-8848438)
p-Y88-CDKN1B [nucleoplasm]
(R-HSA-8942808)
p-T187-CDKN1B [nucleoplasm]
(R-HSA-187525)
CDKN1B [nucleoplasm]
(R-HSA-182563)
0.788
6
UniProt:O76024 WFS1
3
WFS1 [endoplasmic reticulum lumen]
(R-HSA-8956747)
p-WFS1 [endoplasmic reticulum lumen]
(R-HSA-8956998)
WFS1 [endoplasmic reticulum membrane]
(R-HSA-535474)
0.556
3
UniProt:P42858 HTT
1
HTT [nucleoplasm]
(R-HSA-9023590)
0.556
6
UniProt:P61024 CKS1B
1
CKS1B [nucleoplasm]
(R-HSA-187533)
0.527
2
UniProt:P12004 PCNA
5
monoSUMO1-K164,K254,K-PCNA [nucleoplasm]
(R-HSA-4615861)
K63polyUb-K164-PCNA [nucleoplasm]
(R-HSA-8943000)
ISG-K164,ISG-K168-PCNA [nucleoplasm]
(R-HSA-5653768)
MonoUb-K164-PCNA [nucleoplasm]
(R-HSA-5651986)
PCNA [nucleoplasm]
(R-HSA-68439)
0.527
3
UniProt:Q08999 RBL2
2
RBL2 [nucleoplasm]
(R-HSA-389102)
p-T401,S672,S1035-RBL2 [nucleoplasm]
(R-HSA-1226084)
0.462
3
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