Reactome | ENPP6 hydrolyzes lysophosphatidylcholine

ENPP6 hydrolyzes lysophosphatidylcholine

Stable Identifier

R-HSA-6814797

Type

Reaction [transition]

Species

Homo sapiens

Compartment

plasma membrane, extracellular region

ReviewStatus

5/5

Locations in the PathwayBrowser

Expand all

General

SBML | | PDF

SVG | | PPTX | SBGN

ENPP6 hydrolyzes lysophosphatidylcholine

Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout

ENPP6 (Ectonucleotide pyrophosphatase/phosphodiesterase family member 6) associated with the plasma membrane catalyzes the hydrolysis of lysophosphatidylcholine to ChoP (phosphocholine) and MAG (monoacylglycerol), as demonstrated by characterization of the recombinant human protein expressed in cells in culture (Sakagami et al. 2005).

Literature References

PubMed ID	Title	Journal	Year
15788404	Biochemical and molecular characterization of a novel choline-specific glycerophosphodiester phosphodiesterase belonging to the nucleotide pyrophosphatase/phosphodiesterase family Sakagami, H, Aoki, J, Natori, Y, Nishikawa, K, Kakehi, Y, Natori, Y, Arai, H	J. Biol. Chem.	2005