ENPP6 hydrolyzes lysophosphatidylcholine

Stable Identifier
R-HSA-6814797
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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ENPP6 (Ectonucleotide pyrophosphatase/phosphodiesterase family member 6) associated with the plasma membrane catalyzes the hydrolysis of lysophosphatidylcholine to ChoP (phosphocholine) and MAG (monoacylglycerol), as demonstrated by characterization of the recombinant human protein expressed in cells in culture (Sakagami et al. 2005).

Literature References
PubMed ID Title Journal Year
15788404 Biochemical and molecular characterization of a novel choline-specific glycerophosphodiester phosphodiesterase belonging to the nucleotide pyrophosphatase/phosphodiesterase family

Sakagami, H, Aoki, J, Natori, Y, Nishikawa, K, Kakehi, Y, Natori, Y, Arai, H

J. Biol. Chem. 2005
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
glycerophosphocholine cholinephosphodiesterase activity of ENPP6 [plasma membrane]
Physical Entity
Activity
Orthologous Events
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