Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
LCE1E [cytosol]
Stable Identifier
R-HSA-6814299
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Late cornified envelope protein 1E, LCE1E_HUMAN
Locations in the PathwayBrowser
Expand all
Developmental Biology (Homo sapiens)
Keratinization (Homo sapiens)
Formation of the cornified envelope (Homo sapiens)
CASP14 cleaves filaggrin (Homo sapiens)
Late cornified envelope [plasma membrane] (Homo sapiens)
Late envelope proteins [cytosol] (Homo sapiens)
LCE1E [cytosol] (Homo sapiens)
Mature cornified envelope [plasma membrane] (Homo sapiens)
Late envelope proteins [cytosol] (Homo sapiens)
LCE1E [cytosol] (Homo sapiens)
Late envelope proteins bind cornified envelope:CDSN (Homo sapiens)
Late cornified envelope [plasma membrane] (Homo sapiens)
Late envelope proteins [cytosol] (Homo sapiens)
LCE1E [cytosol] (Homo sapiens)
Late envelope proteins [cytosol] (Homo sapiens)
LCE1E [cytosol] (Homo sapiens)
Plasma membrane resorption (Homo sapiens)
Mature cornified envelope [cornified envelope] (Homo sapiens)
Late envelope proteins [cytosol] (Homo sapiens)
LCE1E [cytosol] (Homo sapiens)
Mature cornified envelope [plasma membrane] (Homo sapiens)
Late envelope proteins [cytosol] (Homo sapiens)
LCE1E [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q5T753 LCE1E
Gene Names
LCE1E, LEP5
Chain
chain:1-118
Reference Genes
BioGPS Gene:353135 LCE1E
COSMIC (genes):LCE1E LCE1E
CTD Gene:353135 LCE1E
dbSNP Gene:353135 LCE1E
ENSEMBL:ENSG00000186226 LCE1E
HGNC:29466 LCE1E
KEGG:hsa:353135 LCE1E
Monarch:353135 LCE1E
NCBI Gene:353135 LCE1E
OMIM:612607 LCE1E
UCSC:Q5T753 LCE1E
Reference Transcript
RefSeq:NM_178353.1 LCE1E
Other Identifiers
11735685_at
1559224_PM_at
1559224_at
1559226_PM_x_at
1559226_x_at
16671068
2359434
2359435
2359436
2359438
2435839
353135
7905519
A_14_P131413
A_14_P200037
A_23_P339691
A_33_P3356811
GE475718
GO:0005515
GO:0008544
GO:0031424
GO:0042802
GO:0048856
HMNXSV003000848
Hs2.250236.1.S1_3p_s_at
ILMN_1668386
ILMN_1689849
ILMN_1769684
PH_hs_0027324
TC01001238.hg
TC01004750.hg
Participates
as a candidate of
Late envelope proteins [cytosol] (Homo sapiens)
Cross References
ENSEMBL
ENST00000368770
,
ENSP00000357759
,
ENST00000368771
,
ENSP00000357760
,
ENSG00000186226
OpenTargets
ENSG00000186226
GeneCards
LCE1E
HPA
ENSG00000186226-LCE1E
PRO
Q5T753
Pharos - Targets
Q5T753
Interactors (3)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P22735 TGM1
3
TGM1 [cytosol]
(R-HSA-6813756)
TGM1 [cornified envelope]
(R-HSA-8847706)
TGM1 [plasma membrane]
(R-HSA-6813757)
0.556
3
UniProt:O75928-2 PIAS2
1
PIAS2-2 [nucleoplasm]
(R-HSA-2993779)
0.556
3
UniProt:P0DPK4 NOTCH2NLC
1
NOTCH2NLC [extracellular region]
(R-HSA-9908932)
0.556
3
© 2025
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text