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LCE1B [cytosol]
Stable Identifier
R-HSA-6814271
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Late cornified envelope protein 1B, LCE1B_HUMAN
Locations in the PathwayBrowser
Expand all
Developmental Biology (Homo sapiens)
Keratinization (Homo sapiens)
Formation of the cornified envelope (Homo sapiens)
CASP14 cleaves filaggrin (Homo sapiens)
Late cornified envelope [plasma membrane] (Homo sapiens)
Late envelope proteins [cytosol] (Homo sapiens)
LCE1B [cytosol] (Homo sapiens)
Mature cornified envelope [plasma membrane] (Homo sapiens)
Late envelope proteins [cytosol] (Homo sapiens)
LCE1B [cytosol] (Homo sapiens)
Late envelope proteins bind cornified envelope:CDSN (Homo sapiens)
Late cornified envelope [plasma membrane] (Homo sapiens)
Late envelope proteins [cytosol] (Homo sapiens)
LCE1B [cytosol] (Homo sapiens)
Late envelope proteins [cytosol] (Homo sapiens)
LCE1B [cytosol] (Homo sapiens)
Plasma membrane resorption (Homo sapiens)
Mature cornified envelope [cornified envelope] (Homo sapiens)
Late envelope proteins [cytosol] (Homo sapiens)
LCE1B [cytosol] (Homo sapiens)
Mature cornified envelope [plasma membrane] (Homo sapiens)
Late envelope proteins [cytosol] (Homo sapiens)
LCE1B [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q5T7P3 LCE1B
Gene Names
LCE1B, LEP2, SPRL2A
Chain
chain:1-118
Reference Genes
BioGPS Gene:353132 LCE1B
COSMIC (genes):LCE1B LCE1B
CTD Gene:353132 LCE1B
dbSNP Gene:353132 LCE1B
ENSEMBL:ENSG00000196734 LCE1B
ENSEMBL_homo_sapiens_GENE:ENSG00000196734.9 LCE1B
HGNC:16611 LCE1B
KEGG Gene (Homo sapiens):353132 LCE1B
Monarch:353132 LCE1B
NCBI Gene:353132 LCE1B
OMIM:612604 LCE1B
UCSC:Q5T7P3 LCE1B
Reference Transcript
RefSeq:NM_178349.1 LCE1B
Other Identifiers
11737945_x_at
1560531_PM_at
1560531_at
16671077
2359330
2359445
2359446
2359447
2359448
2435837
353132
7905525
A_14_P134645
A_23_P368862
A_33_P3356816
GE515255
GO:0005515
GO:0008544
GO:0030154
GO:0031424
GO:0042802
GO:0048856
HMNXSV003017248
Hs2.375103.1.S1_3p_at
ILMN_1736655
PH_hs_0018211
TC01001240.hg
TC01004751.hg
Participates
as a candidate of
Late envelope proteins [cytosol] (Homo sapiens)
Cross References
RefSeq
NP_848126.1
OpenTargets
ENSG00000196734
GeneCards
Q5T7P3
HPA
ENSG00000196734-LCE1B
Ensembl
ENSG00000196734
,
ENST00000360090
,
ENSP00000353203
PRO
Q5T7P3
Pharos - Targets
Q5T7P3
Interactors (6)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P49639 HOXA1
1
HOXA1 [nucleoplasm]
(R-HSA-5617464)
0.83
13
UniProt:O43597 SPRY2
8
p-Y55-SPRY2 [cytosol]
(R-HSA-182950)
p-Y55,Y227-SPRY2 [plasma membrane]
(R-HSA-1295629)
p-S111,S120-SPRY2 [cytosol]
(R-HSA-1295590)
p-Y55,Y227-SPRY2 [plasma membrane]
(R-HSA-934555)
SPRY2 [plasma membrane]
(R-HSA-182924)
p-S112,S121-SPRY2 [plasma membrane]
(R-HSA-934595)
SPRY2 [cytosol]
(R-HSA-182949)
p-S112,S115-SPRY2 [cytosol]
(R-HSA-1295619)
0.742
5
UniProt:P42858 HTT
1
HTT [nucleoplasm]
(R-HSA-9023590)
0.556
15
UniProt:O76024 WFS1
3
WFS1 [endoplasmic reticulum lumen]
(R-HSA-8956747)
p-WFS1 [endoplasmic reticulum lumen]
(R-HSA-8956998)
WFS1 [endoplasmic reticulum membrane]
(R-HSA-535474)
0.556
3
UniProt:P22735 TGM1
3
TGM1 [cytosol]
(R-HSA-6813756)
TGM1 [cornified envelope]
(R-HSA-8847706)
TGM1 [plasma membrane]
(R-HSA-6813757)
0.556
3
UniProt:P07237 P4HB
3
P4HB [endoplasmic reticulum lumen]
(R-HSA-174692)
p-P4HB [endoplasmic reticulum lumen]
(R-HSA-8956902)
HC53,56-P4HB [endoplasmic reticulum lumen]
(R-HSA-3341287)
0.556
3
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