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COG3 [trans-Golgi network membrane]
Stable Identifier
R-HSA-6813865
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
trans-Golgi network membrane
Synonyms
Conserved oligomeric Golgi complex subunit 3, COG3_HUMAN
Locations in the PathwayBrowser
Expand all
Vesicle-mediated transport (Homo sapiens)
Membrane Trafficking (Homo sapiens)
Intra-Golgi and retrograde Golgi-to-ER traffic (Homo sapiens)
Retrograde transport at the Trans-Golgi-Network (Homo sapiens)
Fusion of early-endosome derived vesicles at the TGN (Homo sapiens)
COG complex [trans-Golgi network membrane] (Homo sapiens)
COG3 [trans-Golgi network membrane] (Homo sapiens)
RAB6:GTP:RIC1:RGP1:GARP complex:COG complex:AcM-ARFRP1:GTP:SYS1:MyrG-ARL1:GTP:Golgin dimers:STX6:STX16:VTI1A:VAMP4:early endosome-to-TGN cargo [trans-Golgi network membrane] (Homo sapiens)
COG complex [trans-Golgi network membrane] (Homo sapiens)
COG3 [trans-Golgi network membrane] (Homo sapiens)
RAB6:GTP binds the GARP and COG complexes, t-SNAREs and endosome-derived vesicles (Homo sapiens)
COG complex [trans-Golgi network membrane] (Homo sapiens)
COG3 [trans-Golgi network membrane] (Homo sapiens)
RAB6:GTP:RIC1:RGP1:GARP complex:COG complex:AcM-ARFRP1:GTP:SYS1:MyrG-ARL1:GTP:Golgin dimers:STX6:STX16:VTI1A:VAMP4:early endosome-to-TGN cargo [trans-Golgi network membrane] (Homo sapiens)
COG complex [trans-Golgi network membrane] (Homo sapiens)
COG3 [trans-Golgi network membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q96JB2 COG3
Gene Names
COG3, SEC34
Chain
initiator methionine:, chain:2-828
Reference Genes
BioGPS Gene:83548 COG3
COSMIC (genes):COG3 COG3
CTD Gene:83548 COG3
dbSNP Gene:83548 COG3
ENSEMBL:ENSG00000136152 COG3
ENSEMBL_homo_sapiens_GENE:ENSG00000136152.15 COG3
HGNC:18619 COG3
KEGG Gene (Homo sapiens):83548 COG3
Monarch:83548 COG3
NCBI Gene:83548 COG3
OMIM:606975 COG3
UCSC:Q96JB2 COG3
Reference Transcript
RefSeq:NM_031431.3 COG3
Other Identifiers
11745418_a_at
11748993_a_at
11749384_a_at
11755159_a_at
1554339_PM_a_at
1554339_a_at
16774551
223450_PM_s_at
223450_s_at
3488254
3488255
3488256
3488257
3488265
3488266
3488267
3488268
3488269
3488270
3488271
3488273
3488274
3488275
3488277
3488278
3488279
3488281
3488282
3488285
3488287
3488290
3488292
3488294
3488295
3488301
3488303
3488305
3488307
3488309
3488315
3488316
3488317
3488318
7968931
83548
86759_at
91712_at
A_14_P119032
A_14_P123918
A_24_P296070
A_24_P42613
GE54879
GO:0000139
GO:0000301
GO:0005515
GO:0005794
GO:0005801
GO:0005829
GO:0005886
GO:0006486
GO:0006886
GO:0006888
GO:0006890
GO:0006891
GO:0007030
GO:0015031
GO:0016020
GO:0016192
GO:0017119
GO:0032580
GO:0032588
GO:0033365
GO:0036211
GO:0043226
GO:0050821
GO:0070085
GO:1901135
HMNXSV003030107
HMNXSV003034694
Hs2.13392.2.A1_3p_s_at
ILMN_1776154
ILMN_2129715
PH_hs_0022268
TC13000176.hg
g12744920_3p_a_at
Participates
as a component of
COG complex [trans-Golgi network membrane] (Homo sapiens)
Other forms of this molecule
COG3 [Golgi membrane]
Inferred To
cog3 [trans-Golgi network membrane]
(Dictyostelium discoideum)
COG3 [trans-Golgi network membrane]
(Bos taurus)
COG3 [trans-Golgi network membrane]
(Canis familiaris)
COG3 [trans-Golgi network membrane]
(Gallus gallus)
COG3 [trans-Golgi network membrane]
(Saccharomyces cerevisiae)
COG3 [trans-Golgi network membrane]
(Sus scrofa)
Cog3 [trans-Golgi network membrane]
(Drosophila melanogaster)
Cog3 [trans-Golgi network membrane]
(Mus musculus)
Cog3 [trans-Golgi network membrane]
(Rattus norvegicus)
cogc-3 [trans-Golgi network membrane]
(Caenorhabditis elegans)
Cross References
RefSeq
NP_113619.2
OpenTargets
ENSG00000136152
HPA
ENSG00000136152-COG3
GeneCards
Q96JB2
Ensembl
ENST00000349995
,
ENST00000617493
,
ENSG00000136152
,
ENSP00000481332
,
ENSP00000258654
PRO
Q96JB2
Pharos - Targets
Q96JB2
Interactors (4)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P0DTC7 7a
5
7a [endolysosome membrane]
(R-COV-9755945)
7a [endoplasmic reticulum membrane]
(R-COV-9727308)
7a [endoplasmic reticulum-Golgi intermediate compartment membrane]
(R-COV-9694750)
7a [endocytic vesicle membrane]
(R-COV-9694645)
7a [virion membrane]
(R-COV-9694648)
0.547
2
UniProt:Q9NZQ7 CD274
1
CD274 [plasma membrane]
(R-HSA-3211776)
0.527
2
UniProt:Q15814 TBCC
1
TBCC [cytosol]
(R-HSA-379537)
0.527
2
UniProt:Q8WVM8 SCFD1
1
SCFD1 [cytosol]
(R-HSA-5688147)
0.462
2
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