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RAB6:GTP:RIC1:RGP1 [trans-Golgi network membrane]
Stable Identifier
R-HSA-6811353
Type
Complex
Species
Homo sapiens
Compartment
trans-Golgi network membrane
Locations in the PathwayBrowser
Expand all
Vesicle-mediated transport (Homo sapiens)
Membrane Trafficking (Homo sapiens)
Intra-Golgi and retrograde Golgi-to-ER traffic (Homo sapiens)
Retrograde transport at the Trans-Golgi-Network (Homo sapiens)
Fusion of early-endosome derived vesicles at the TGN (Homo sapiens)
RAB6:GTP:RIC1:RGP1:GARP complex:COG complex:AcM-ARFRP1:GTP:SYS1:MyrG-ARL1:GTP:Golgin dimers:STX6:STX16:VTI1A:VAMP4:early endosome-to-TGN cargo [trans-Golgi network membrane] (Homo sapiens)
RAB6:GTP:RIC1:RGP1 [trans-Golgi network membrane] (Homo sapiens)
RAB6:GTP binds the GARP and COG complexes, t-SNAREs and endosome-derived vesicles (Homo sapiens)
RAB6:GTP:RIC1:RGP1 [trans-Golgi network membrane] (Homo sapiens)
RAB6:GTP:RIC1:RGP1:GARP complex:COG complex:AcM-ARFRP1:GTP:SYS1:MyrG-ARL1:GTP:Golgin dimers:STX6:STX16:VTI1A:VAMP4:early endosome-to-TGN cargo [trans-Golgi network membrane] (Homo sapiens)
RAB6:GTP:RIC1:RGP1 [trans-Golgi network membrane] (Homo sapiens)
RIC1:RGP1 stimulates nucleotide RAB6 nucleotide exchange (Homo sapiens)
RAB6:GTP:RIC1:RGP1 [trans-Golgi network membrane] (Homo sapiens)
Literature References
PubMed ID
Title
Journal
Year
23091056
Ric1-Rgp1 complex is a guanine nucleotide exchange factor for the late Golgi Rab6A GTPase and an effector of the medial Golgi Rab33B GTPase
Pfeffer, SR
,
Luchetti, G
,
Pusapati, GV
J. Biol. Chem.
2012
10990452
Ric1p and Rgp1p form a complex that catalyses nucleotide exchange on Ypt6p
Pelham, HR
,
Siniossoglou, S
,
Peak-Chew, SY
EMBO J.
2000
Participants
components
RAB6:GTP [trans-Golgi network membrane]
(Homo sapiens)
RIC1:RGP1 [trans-Golgi network membrane]
(Homo sapiens)
Participates
as an output of
RIC1:RGP1 stimulates nucleotide RAB6 nucleotide exchange (Homo sapiens)
as a component of
RAB6:GTP:RIC1:RGP1:GARP complex:COG complex:AcM-ARFRP1:GTP:SYS1:MyrG-ARL1:GTP:Golgin dimers:STX6:STX16:VTI1A:VAMP4:early endosome-to-TGN cargo [trans-Golgi network membrane] (Homo sapiens)
as an input of
RAB6:GTP binds the GARP and COG complexes, t-SNAREs and endosome-derived vesicles (Homo sapiens)
Inferred To
RAB6:GTP:RIC1:RGP1 [trans-Golgi network membrane]
(Bos taurus)
RAB6:GTP:RIC1:RGP1 [trans-Golgi network membrane]
(Caenorhabditis elegans)
RAB6:GTP:RIC1:RGP1 [trans-Golgi network membrane]
(Canis familiaris)
RAB6:GTP:RIC1:RGP1 [trans-Golgi network membrane]
(Dictyostelium discoideum)
RAB6:GTP:RIC1:RGP1 [trans-Golgi network membrane]
(Drosophila melanogaster)
RAB6:GTP:RIC1:RGP1 [trans-Golgi network membrane]
(Gallus gallus)
RAB6:GTP:RIC1:RGP1 [trans-Golgi network membrane]
(Mus musculus)
RAB6:GTP:RIC1:RGP1 [trans-Golgi network membrane]
(Rattus norvegicus)
RAB6:GTP:RIC1:RGP1 [trans-Golgi network membrane]
(Saccharomyces cerevisiae)
RAB6:GTP:RIC1:RGP1 [trans-Golgi network membrane]
(Schizosaccharomyces pombe)
RAB6:GTP:RIC1:RGP1 [trans-Golgi network membrane]
(Sus scrofa)
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