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VPS53 [trans-Golgi network membrane]
Stable Identifier
R-HSA-6811031
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
trans-Golgi network membrane
Synonyms
Vacuolar protein sorting-associated protein 53 homolog
Locations in the PathwayBrowser
Expand all
Vesicle-mediated transport (Homo sapiens)
Membrane Trafficking (Homo sapiens)
Intra-Golgi and retrograde Golgi-to-ER traffic (Homo sapiens)
Retrograde transport at the Trans-Golgi-Network (Homo sapiens)
Fusion of early-endosome derived vesicles at the TGN (Homo sapiens)
GARP complex [trans-Golgi network membrane] (Homo sapiens)
VPS53 [trans-Golgi network membrane] (Homo sapiens)
RAB6:GTP:RIC1:RGP1:GARP complex:COG complex:AcM-ARFRP1:GTP:SYS1:MyrG-ARL1:GTP:Golgin dimers:STX6:STX16:VTI1A:VAMP4:early endosome-to-TGN cargo [trans-Golgi network membrane] (Homo sapiens)
GARP complex [trans-Golgi network membrane] (Homo sapiens)
VPS53 [trans-Golgi network membrane] (Homo sapiens)
Fusion of late-endosome derived vesicles at the TGN (Homo sapiens)
GARP complex [trans-Golgi network membrane] (Homo sapiens)
VPS53 [trans-Golgi network membrane] (Homo sapiens)
RAB9:GTP:p-RABEPK:VAMP3:STX16:STX10:VTI1A:GARP complex:GCC2 dimer:late-endosome-to-TGN cargo [trans-Golgi network membrane] (Homo sapiens)
GARP complex [trans-Golgi network membrane] (Homo sapiens)
VPS53 [trans-Golgi network membrane] (Homo sapiens)
RAB6:GTP binds the GARP and COG complexes, t-SNAREs and endosome-derived vesicles (Homo sapiens)
GARP complex [trans-Golgi network membrane] (Homo sapiens)
VPS53 [trans-Golgi network membrane] (Homo sapiens)
RAB6:GTP:RIC1:RGP1:GARP complex:COG complex:AcM-ARFRP1:GTP:SYS1:MyrG-ARL1:GTP:Golgin dimers:STX6:STX16:VTI1A:VAMP4:early endosome-to-TGN cargo [trans-Golgi network membrane] (Homo sapiens)
GARP complex [trans-Golgi network membrane] (Homo sapiens)
VPS53 [trans-Golgi network membrane] (Homo sapiens)
Tethering of late endosome-derived vesicles by GARP, STX10:ST16:VTI1A and Golgins (Homo sapiens)
GARP complex [trans-Golgi network membrane] (Homo sapiens)
VPS53 [trans-Golgi network membrane] (Homo sapiens)
RAB9:GTP:p-RABEPK:VAMP3:STX16:STX10:VTI1A:GARP complex:GCC2 dimer:late-endosome-to-TGN cargo [trans-Golgi network membrane] (Homo sapiens)
GARP complex [trans-Golgi network membrane] (Homo sapiens)
VPS53 [trans-Golgi network membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q5VIR6 VPS53
Gene Names
VPS53, PP13624
Chain
chain:1-832
Reference Genes
BioGPS Gene:55275 VPS53
COSMIC (genes):VPS53 VPS53
CTD Gene:55275 VPS53
dbSNP Gene:55275 VPS53
ENSEMBL:ENSG00000141252 VPS53
ENSEMBL:ENSG00000283883 VPS53
HGNC:25608 VPS53
KEGG Gene (Homo sapiens):55275 VPS53
Monarch:55275 VPS53
NCBI Gene:55275 VPS53
OMIM:615850 VPS53
UCSC:Q5VIR6 VPS53
Reference Transcript
RefSeq:NM_001128159.2 VPS53
RefSeq:NM_018289.3 VPS53
Other Identifiers
0006100102
11726089_at
11726090_at
11726091_at
11741439_a_at
11748469_x_at
11752530_a_at
11753048_a_at
11753049_x_at
1557112_3p_a_at
1557112_a_at
16839224
219794_3p_at
219794_at
221707_s_at
227229_at
229653_at
235710_at
235882_at
3739648
3739650
3739652
3739654
3739656
3739657
3739659
3739661
3739663
3739664
3739665
3739666
3739667
3739669
3739670
3739671
3739672
3739675
3739676
3739681
3739682
3739685
3739696
3739700
3739702
3739703
3739705
3739709
3739710
3739717
3739718
3739719
3739721
3739722
3739726
3739734
3739735
3739739
3739744
3739745
3739748
3739749
3739750
42054_at
45528_s_at
48464_at
53893_at
55275
63551_at
74054_at
8010918
8010924
91272_at
A_23_P130285
A_24_P147398
A_24_P279489
GE52974
GE55930
GO:0000938
GO:0003674
GO:0005515
GO:0005575
GO:0005622
GO:0005737
GO:0005768
GO:0005794
GO:0005802
GO:0005829
GO:0006810
GO:0007034
GO:0007041
GO:0008150
GO:0010008
GO:0015031
GO:0016020
GO:0016192
GO:0031410
GO:0032456
GO:0032588
GO:0032991
GO:0042147
GO:0043226
GO:0048471
GO:0055037
GO:1990745
Hs.148185.0.S1_3p_at
Hs.20818.0.A1_3p_at
Hs.21475.0.A1_3p_at
Hs.258401.0.A1_3p_at
Hs2.184178.1.S1_3p_x_at
ILMN_1806510
ILMN_1912997
PH_hs_0009019
PH_hs_0039516
TC17000966.hg
TC17002427.hg
g13543951_3p_s_at
g8922801_3p_at
Participant Of
hasComponent
GARP complex [trans-Golgi network membrane]
Inferred To
Vps53 [trans-Golgi network membrane] (Drosophila melanogaster)
Vps53 [trans-Golgi network membrane] (Mus musculus)
Vps53 [trans-Golgi network membrane] (Rattus norvegicus)
VPS53 [trans-Golgi network membrane] (Canis familiaris)
VPS53 [trans-Golgi network membrane] (Dictyostelium discoideum)
VPS53 [trans-Golgi network membrane] (Saccharomyces cerevisiae)
VPS53 [trans-Golgi network membrane] (Sus scrofa)
Ghost homologue of VPS53 [trans-Golgi network membrane] (Gallus gallus)
vps-53 [trans-Golgi network membrane] (Caenorhabditis elegans)
vps53 [trans-Golgi network membrane] (Danio rerio)
vps53 [trans-Golgi network membrane] (Schizosaccharomyces pombe)
vps53 [trans-Golgi network membrane] (Xenopus tropicalis)
Cross References
RefSeq
NP_060759.2
,
NP_001121631.1
OpenTargets
ENSG00000141252
GeneCards
Q5VIR6
HPA
ENSG00000141252-VPS53
Ensembl
ENST00000291074
,
ENSP00000401435
,
ENSP00000492070
,
ENST00000639896
,
ENST00000638350
,
ENSG00000283883
,
ENST00000639801
,
ENST00000437048
,
ENST00000571805
,
ENSP00000492119
,
ENSP00000291074
,
ENSG00000141252
,
ENSP00000459312
,
ENSP00000492761
PRO
Q5VIR6
Orphanet
22820
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