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STX10 [trans-Golgi network membrane]
Stable Identifier
R-HSA-6810999
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
trans-Golgi network membrane
Synonyms
Syntaxin-10, Syn10
Locations in the PathwayBrowser
Expand all
Vesicle-mediated transport (Homo sapiens)
Membrane Trafficking (Homo sapiens)
Intra-Golgi and retrograde Golgi-to-ER traffic (Homo sapiens)
Retrograde transport at the Trans-Golgi-Network (Homo sapiens)
ATP hydrolysis by NSF disassembles the cis-SNARE at the TGN (Homo sapiens)
STX10 [trans-Golgi network membrane] (Homo sapiens)
STX10:STX16:VTI1A:VAMP3:NSF hexamer:SNAPs [trans-Golgi network membrane] (Homo sapiens)
STX10:STX16:VTI1A:VAMP3 [trans-Golgi network membrane] (Homo sapiens)
STX10 [trans-Golgi network membrane] (Homo sapiens)
Fusion of late-endosome derived vesicles at the TGN (Homo sapiens)
RAB9:GTP:p-RABEPK:VAMP3:STX16:STX10:VTI1A:GARP complex:GCC2 dimer:late-endosome-to-TGN cargo [trans-Golgi network membrane] (Homo sapiens)
STX10:STX16:VTI1A [trans-Golgi network membrane] (Homo sapiens)
STX10 [trans-Golgi network membrane] (Homo sapiens)
STX10:STX16:VTI1A:VAMP3 [trans-Golgi network membrane] (Homo sapiens)
STX10 [trans-Golgi network membrane] (Homo sapiens)
SNAPs and NSF hexamer bind cis-SNARE at the TGN (Homo sapiens)
STX10:STX16:VTI1A:VAMP3 [trans-Golgi network membrane] (Homo sapiens)
STX10 [trans-Golgi network membrane] (Homo sapiens)
STX10:STX16:VTI1A:VAMP3:NSF hexamer:SNAPs [trans-Golgi network membrane] (Homo sapiens)
STX10:STX16:VTI1A:VAMP3 [trans-Golgi network membrane] (Homo sapiens)
STX10 [trans-Golgi network membrane] (Homo sapiens)
Tethering of late endosome-derived vesicles by GARP, STX10:ST16:VTI1A and Golgins (Homo sapiens)
RAB9:GTP:p-RABEPK:VAMP3:STX16:STX10:VTI1A:GARP complex:GCC2 dimer:late-endosome-to-TGN cargo [trans-Golgi network membrane] (Homo sapiens)
STX10:STX16:VTI1A [trans-Golgi network membrane] (Homo sapiens)
STX10 [trans-Golgi network membrane] (Homo sapiens)
STX10:STX16:VTI1A [trans-Golgi network membrane] (Homo sapiens)
STX10 [trans-Golgi network membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:O60499 STX10
Gene Names
STX10, SYN10
Chain
initiator methionine:, chain:2-249
Reference Genes
COSMIC (genes):STX10 STX10
dbSNP Gene:8677 STX10
ENSEMBL:ENSG00000104915 STX10
Participates
as an output of
ATP hydrolysis by NSF disassembles the cis-SNARE at the TGN (Homo sapiens)
as a component of
STX10:STX16:VTI1A:VAMP3 [trans-Golgi network membrane] (Homo sapiens)
STX10:STX16:VTI1A [trans-Golgi network membrane] (Homo sapiens)
Inferred To
SYN8 [trans-Golgi network membrane]
(Saccharomyces cerevisiae)
Homologues of STX10 [trans-Golgi network membrane]
(Saccharomyces cerevisiae)
Homologues of STX10 [trans-Golgi network membrane]
(Schizosaccharomyces pombe)
fsv1 [trans-Golgi network membrane]
(Schizosaccharomyces pombe)
Syx6 [trans-Golgi network membrane]
(Drosophila melanogaster)
tlg1 [trans-Golgi network membrane]
(Schizosaccharomyces pombe)
Ghost homologue of STX10 [trans-Golgi network membrane]
(Caenorhabditis elegans)
Ghost homologue of STX10 [trans-Golgi network membrane]
(Gallus gallus)
Ghost homologue of STX10 [trans-Golgi network membrane]
(Mus musculus)
Ghost homologue of STX10 [trans-Golgi network membrane]
(Rattus norvegicus)
Ghost homologue of STX10 [trans-Golgi network membrane]
(Sus scrofa)
STX10 [trans-Golgi network membrane]
(Bos taurus)
STX10 [trans-Golgi network membrane]
(Canis familiaris)
STX10 [trans-Golgi network membrane]
(Schizosaccharomyces pombe)
syn10 [trans-Golgi network membrane]
(Dictyostelium discoideum)
VAM7 [trans-Golgi network membrane]
(Saccharomyces cerevisiae)
TLG1 [trans-Golgi network membrane]
(Saccharomyces cerevisiae)
Interactors (6)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P54920 NAPA
1
NAPA [cytosol]
(R-HSA-264469)
0.643
3
UniProt:O15400 STX7
0.527
4
UniProt:O95183 VAMP5
0.527
3
UniProt:P0DTD8 NS7B
0.527
2
UniProt:Q86Y82 STX12
0.527
4
UniProt:O75379 VAMP4
4
VAMP4 [transport vesicle]
(R-HSA-6811023)
VAMP4 [trans-Golgi network membrane]
(R-HSA-6811021)
VAMP4 [plasma membrane]
(R-HSA-8864461)
VAMP4 [clathrin-coated endocytic vesicle membrane]
(R-HSA-8869133)
0.527
3
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