Reactome | COPZ2 [endoplasmic reticulum membrane]

COPZ2 [endoplasmic reticulum membrane]

Stable Identifier

R-HSA-6810966

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

endoplasmic reticulum membrane

Locations in the PathwayBrowser

Expand all

Vesicle-mediated transport (Homo sapiens)

- Membrane Trafficking (Homo sapiens)
  - Intra-Golgi and retrograde Golgi-to-ER traffic (Homo sapiens)
    - Golgi-to-ER retrograde transport (Homo sapiens)
      - COPI-dependent Golgi-to-ER retrograde traffic (Homo sapiens)
        
        COPI vesicle uncoating at the ER (Homo sapiens)
        
        RAB1:GTP:coatomer:p24 dimers:SEC22B:cargo:NBAS:RINT1:ZW10:STX18:USE1L:BNIP1 [endoplasmic reticulum membrane] (Homo sapiens)
        
        coatomer [endoplasmic reticulum membrane] (Homo sapiens)
        
        tetrameric coatomer complex [endoplasmic reticulum membrane] (Homo sapiens)
        
        COPZ1,2 [endoplasmic reticulum membrane] (Homo sapiens)
        
        COPZ2 [endoplasmic reticulum membrane] (Homo sapiens)
        
        Retrograde vesicle is tethered at the ER by the NRZ complex and t-SNAREs (Homo sapiens)
        
        RAB1:GTP:coatomer:p24 dimers:SEC22B:cargo:NBAS:RINT1:ZW10:STX18:USE1L:BNIP1 [endoplasmic reticulum membrane] (Homo sapiens)
        
        coatomer [endoplasmic reticulum membrane] (Homo sapiens)
        
        tetrameric coatomer complex [endoplasmic reticulum membrane] (Homo sapiens)
        
        COPZ1,2 [endoplasmic reticulum membrane] (Homo sapiens)
        
        COPZ2 [endoplasmic reticulum membrane] (Homo sapiens)

External Reference Information

External Reference

UniProt:Q9P299 COPZ2

Gene Names

COPZ2

Chain

chain:1-210

Reference Genes

BioGPS Gene:51226 COPZ2

COSMIC (genes):COPZ2 COPZ2

CTD Gene:51226 COPZ2

dbSNP Gene:51226 COPZ2

ENSEMBL:ENSG00000005243 COPZ2

HGNC:19356 COPZ2

KEGG:hsa:51226 COPZ2

Monarch:51226 COPZ2

NCBI Gene:51226 COPZ2

OMIM:615526 COPZ2

UCSC:Q9P299 COPZ2

Reference Transcript

RefSeq:NM_016429.3 COPZ2

Other Identifiers

11722963_a_at

16846163

219561_PM_at

219561_at

235897_PM_at

235897_at

3761071

3761072

3761074

3761075

3761076

3761077

3761079

3761080

3761081

3761082

3761084

3761085

3761086

3761087

3761088

3761093

48943_at

51226

51960_at

8016390

A_23_P101093

GE79046

GO:0000139

GO:0005737

GO:0005789

GO:0005794

GO:0005801

GO:0005829

GO:0006886

GO:0006890

GO:0006891

GO:0015031

GO:0016020

GO:0016192

GO:0030126

GO:0030133

GO:0030663

GO:0031410

GO:0033116

GO:0043226

HMNXSV003052793

Hs.96822.0.A1_3p_at

ILMN_1667361

PH_hs_0002952

TC17001633.hg

g7705982_3p_at

Participates

as a member of

COPZ1,2 [endoplasmic reticulum membrane] (Homo sapiens)

Other forms of this molecule

COPZ2 [Golgi membrane]

COPZ2 [transport vesicle]

COPZ2 [cytosol]

Inferred To

Copz2 [endoplasmic reticulum membrane] (Mus musculus)

Copz2 [endoplasmic reticulum membrane] (Rattus norvegicus)

copZb [endoplasmic reticulum membrane] (Dictyostelium discoideum)

ret3 [endoplasmic reticulum membrane] (Schizosaccharomyces pombe)

copz-1 [endoplasmic reticulum membrane] (Caenorhabditis elegans)

copz2 [endoplasmic reticulum membrane] (Danio rerio)

copz2 [endoplasmic reticulum membrane] (Xenopus tropicalis)

RET3 [endoplasmic reticulum membrane] (Saccharomyces cerevisiae)

COPZ2 [endoplasmic reticulum membrane] (Bos taurus)

COPZ2 [endoplasmic reticulum membrane] (Canis familiaris)

COPZ2 [endoplasmic reticulum membrane] (Sus scrofa)

zetaCOP [endoplasmic reticulum membrane] (Drosophila melanogaster)

Cross References

ENSEMBL

ENSP00000480707, ENST00000621465

OpenTargets

ENSG00000005243

HPA

ENSG00000005243-COPZ2

PRO

Q9P299

Pharos - Targets

Q9P299