Reactome | KRTAP12-4 [cytosol]

KRTAP12-4 [cytosol]

Stable Identifier

R-HSA-6810278

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Keratin-associated protein 12-4, KR124_HUMAN

Locations in the PathwayBrowser

Expand all

Developmental Biology (Homo sapiens)

- Keratinization (Homo sapiens)
  - Formation of hair keratin fibres (Homo sapiens)
    - Keratin associated proteins [cytosol] (Homo sapiens)
      - KRTAP12s [cytosol] (Homo sapiens)
        
        KRTAP12-4 [cytosol] (Homo sapiens)
    - Keratin tonofilament:Keratin associated proteins polymer [cytosol] (Homo sapiens)
      - Keratin tonofilament, KAPs [cytosol] (Homo sapiens)
        
        Keratin associated proteins [cytosol] (Homo sapiens)
        
        KRTAP12s [cytosol] (Homo sapiens)
        
        KRTAP12-4 [cytosol] (Homo sapiens)

External Reference Information

External Reference

UniProt:P60329 KRTAP12-4

Gene Names

KRTAP12-4, KAP12.4, KRTAP12.4

Chain

chain:1-112

Reference Genes

BioGPS Gene:386684 KRTAP12-4

COSMIC (genes):KRTAP12-4 KRTAP12-4

CTD Gene:386684 KRTAP12-4

dbSNP Gene:386684 KRTAP12-4

ENSEMBL:ENSG00000212933 KRTAP12-4

HGNC:20532 KRTAP12-4

Monarch:386684 KRTAP12-4

NCBI Gene:386684 KRTAP12-4

UCSC:P60329 KRTAP12-4

Reference Transcript

RefSeq:NM_198698.1 KRTAP12-4

Other Identifiers

11742177_at

11742178_x_at

16926399

386684

3934617

3934618

3934619

3934620

3934621

8070789

A_33_P3354394

GO:0005515

GO:0005829

GO:0005882

HMNXSV003026238

ILMN_1780422

PH_hs_0034604

TC21000532.hg

Participates

as a member of

KRTAP12s [cytosol] (Homo sapiens)

Inferred To

LOC110256282 [cytosol] (Sus scrofa)

KRTAP12-2 [cytosol] (Bos taurus)

LOC106508044 [cytosol] (Sus scrofa)

Homologues of KRTAP12-4 [cytosol] (Bos taurus)

Homologues of KRTAP12-4 [cytosol] (Mus musculus)

Homologues of KRTAP12-4 [cytosol] (Sus scrofa)

LOC610887 [cytosol] (Canis familiaris)

Krtap12-21 [cytosol] (Mus musculus)

KRTAP12-4 [cytosol] (Bos taurus)

Krtap12-20 [cytosol] (Mus musculus)

Krtap12-22 [cytosol] (Mus musculus)

Krtap12-1 [cytosol] (Mus musculus)

Cross References

ENSEMBL

ENSP00000375476, ENST00000391618

OpenTargets

ENSG00000212933

HPA

ENSG00000212933-KRTAP12-4

PRO

P60329

Pharos - Targets

P60329

Interactors (6)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P49639 HOXA1	1	HOXA1 [nucleoplasm] (R-HSA-5617464)	0.718	10
UniProt:O95231 VENTX	1	VENTX [nucleoplasm] (R-HSA-8853887)	0.666	4
UniProt:Q12837 POU4F2	1	POU4F2 [nucleoplasm] (R-HSA-6804414)	0.556	3
UniProt:Q7Z3S9 NOTCH2NLA	3	NOTCH2NLA [extracellular region] (R-HSA-9908935) NOTCH2NLA(1-?) [extracellular region] (R-HSA-9911493) NOTCH2NLA(?-236) [extracellular region] (R-HSA-9911490)	0.556	3
UniProt:Q92570 NR4A3	1	NR4A3 [nucleoplasm] (R-HSA-8938004)	0.556	3
UniProt:P0DPK4 NOTCH2NLC	1	NOTCH2NLC [extracellular region] (R-HSA-9908932)	0.556	3

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