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SBF2 [cytosol]
Stable Identifier
R-HSA-6809792
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Myotubularin-related protein 13, MTMR13, SET-binding factor 2, CMT4B2
Locations in the PathwayBrowser
Expand all
Metabolism (Homo sapiens)
Metabolism of lipids (Homo sapiens)
Phospholipid metabolism (Homo sapiens)
PI Metabolism (Homo sapiens)
Synthesis of PIPs at the plasma membrane (Homo sapiens)
MTMR2 binds SBF2 (Homo sapiens)
MTMR2:SBF2 Tetramer [cytosol] (Homo sapiens)
SBF2 homodimer [cytosol] (Homo sapiens)
SBF2 [cytosol] (Homo sapiens)
SBF2 homodimer [cytosol] (Homo sapiens)
SBF2 [cytosol] (Homo sapiens)
PI(3,5)P2 is dephosphorylated to PI5P by the MTMR2:SBF2 tetramer at the plasma membrane (Homo sapiens)
MTMR2:SBF2 Tetramer [cytosol] (Homo sapiens)
SBF2 homodimer [cytosol] (Homo sapiens)
SBF2 [cytosol] (Homo sapiens)
PI3P is dephosphorylated to PI by the MTMR2:SBF2 tetramer at the plasma membrane (Homo sapiens)
MTMR2:SBF2 Tetramer [cytosol] (Homo sapiens)
SBF2 homodimer [cytosol] (Homo sapiens)
SBF2 [cytosol] (Homo sapiens)
Vesicle-mediated transport (Homo sapiens)
Membrane Trafficking (Homo sapiens)
Rab regulation of trafficking (Homo sapiens)
RAB GEFs exchange GTP for GDP on RABs (Homo sapiens)
RAB21 GEFs exchange GTP for GDP on RAB21 (Homo sapiens)
RAB21 GEFs [cytosol] (Homo sapiens)
SBF2 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q86WG5 SBF2
Gene Names
SBF2, CMT4B2, KIAA1766, MTMR13
Chain
chain:1-1849
Reference Genes
BioGPS Gene:81846 SBF2
COSMIC (genes):SBF2 SBF2
CTD Gene:81846 SBF2
dbSNP Gene:81846 SBF2
ENSEMBL:ENSG00000133812 SBF2
HGNC:2135 SBF2
Monarch:81846 SBF2
NCBI Gene:81846 SBF2
OMIM:607697 SBF2
UCSC:Q86WG5 SBF2
Reference Transcript
RefSeq:NM_030962.3 SBF2
Other Identifiers
11739476_a_at
11739477_a_at
11739478_s_at
16735669
217202_PM_s_at
217202_s_at
226169_PM_at
226169_at
233914_PM_s_at
233914_s_at
242935_PM_at
242935_at
2447073
3167637
3362465
3362467
3362469
3362470
3362471
3362472
3362473
3362474
3362475
3362476
3362477
3362478
3362479
3362480
3362481
3362482
3362483
3362484
3362485
3362486
3362487
3362488
3362489
3362490
3362491
3362494
3362495
3362496
3362499
3362500
3362502
3362503
3362506
3362507
3362508
3362509
3362512
3362514
3362515
3362517
3362518
3362519
3362520
3362522
3362523
3362524
3362525
3362526
3362527
3362528
3362529
3362531
3362532
3362534
3362537
3362546
3362547
3362548
3362549
3362550
3362551
3362552
3362553
3362554
3362555
3362556
3362558
3362561
3362562
3362564
3362565
3362566
3362567
3362568
3362570
3362572
3362573
3362575
3362576
3362577
3362578
3362579
3362580
3362581
3362582
3362583
3362584
3362585
3362610
3362612
3362613
3362626
3362627
3362653
3362654
44824_at
59668_at
70525_at
79222_r_at
7946516
81846
84424_at
A_23_P419795
A_24_P324630
GE61806
GE624626
GO:0005085
GO:0005515
GO:0005737
GO:0005768
GO:0005774
GO:0005829
GO:0006914
GO:0008289
GO:0010008
GO:0016020
GO:0019208
GO:0019902
GO:0030424
GO:0031410
GO:0035091
GO:0042552
GO:0042802
GO:0042995
GO:0043226
GO:0048471
GO:0098772
HMNXSV003026755
Hs.210322.1.S1_3p_a_at
Hs.247984.0.S1_3p_s_at
Hs.289018.0.S1_3p_at
ILMN_1784595
ILMN_2123665
PH_hs_0025693
TC11001407.hg
Participates
as a member of
RAB21 GEFs [cytosol] (Homo sapiens)
as a component of
SBF2 homodimer [cytosol] (Homo sapiens)
Inferred To
Homologues of SBF2 [cytosol]
(Dictyostelium discoideum)
mtm-5 [cytosol]
(Caenorhabditis elegans)
Sbf [cytosol]
(Drosophila melanogaster)
Sbf2 [cytosol]
(Mus musculus)
Sbf2 [cytosol]
(Rattus norvegicus)
SBF2 [cytosol]
(Bos taurus)
SBF2 [cytosol]
(Dictyostelium discoideum)
SBF2 [cytosol]
(Gallus gallus)
Cross References
ENSEMBL
ENST00000533770
,
ENSP00000256190
,
ENSP00000509247
,
ENST00000256190
OpenTargets
ENSG00000133812
HPA
ENSG00000133812-SBF2
PRO
Q86WG5
Pharos - Targets
Q86WG5
Orphanet
SBF2
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q13614 MTMR2
1
MTMR2 [cytosol]
(R-HSA-1604662)
0.569
4
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