MTM1 forms a complex with MTMR12 (3 PAP), an enzymatically inactive myotubularin family member. MTMR12 promotes MTM1 recruitment to cytosolic vesicular structures, presumably early or late endosomes. Complex formation stabilizes both MTM1 and MTMR12 proteins (Caldwell et al. 1991, Nandurkar et al. 2003, Gupta et al. 2013).
Gundry, SR, Gupta, VA, Smith, LL, Shimazu, J, McIntire, JE, Talbot, EA, Goldman, NE, Beggs, AH, Amoasii, L, Laporte, J, Hnia, K, Bass, JR
Majerus, PW, Lips, DL, Caldwell, KK, Bansal, VS
Corcoran, L, Majerus, PW, Mitchell, CA, Selan, C, Layton, M, Mochizuki, Y, Caldwell, KK, Laporte, J, Nandurkar, HH
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