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About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
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Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
Linking to Us
Citing us
Tools
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Analyse gene list
Analyse gene expression
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KRT40 [cytosol]
Stable Identifier
R-HSA-6809605
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Keratin, type I cytoskeletal 40, K1C40_HUMAN
Locations in the PathwayBrowser
Expand all
Developmental Biology (Homo sapiens)
Keratinization (Homo sapiens)
Formation of hair keratin fibres (Homo sapiens)
Keratin tonofilament [cytosol] (Homo sapiens)
Keratin filament [cytosol] (Homo sapiens)
Keratin filament units [cytosol] (Homo sapiens)
Keratin tetramer [cytosol] (Homo sapiens)
Keratin heterodimer [cytosol] (Homo sapiens)
Keratin type I [cytosol] (Homo sapiens)
Keratin type I, hair specific [cytosol] (Homo sapiens)
KRT40 [cytosol] (Homo sapiens)
Keratin unit length filament [cytosol] (Homo sapiens)
Keratin tetramer [cytosol] (Homo sapiens)
Keratin heterodimer [cytosol] (Homo sapiens)
Keratin type I [cytosol] (Homo sapiens)
Keratin type I, hair specific [cytosol] (Homo sapiens)
KRT40 [cytosol] (Homo sapiens)
Keratin tonofilament:Keratin associated proteins polymer [cytosol] (Homo sapiens)
Keratin tonofilament, KAPs [cytosol] (Homo sapiens)
Keratin tonofilament [cytosol] (Homo sapiens)
Keratin filament [cytosol] (Homo sapiens)
Keratin filament units [cytosol] (Homo sapiens)
Keratin tetramer [cytosol] (Homo sapiens)
Keratin heterodimer [cytosol] (Homo sapiens)
Keratin type I [cytosol] (Homo sapiens)
Keratin type I, hair specific [cytosol] (Homo sapiens)
KRT40 [cytosol] (Homo sapiens)
Keratin unit length filament [cytosol] (Homo sapiens)
Keratin tetramer [cytosol] (Homo sapiens)
Keratin heterodimer [cytosol] (Homo sapiens)
Keratin type I [cytosol] (Homo sapiens)
Keratin type I, hair specific [cytosol] (Homo sapiens)
KRT40 [cytosol] (Homo sapiens)
Formation of the cornified envelope (Homo sapiens)
CASP14 cleaves filaggrin (Homo sapiens)
Late cornified envelope [plasma membrane] (Homo sapiens)
Cornified envelope:CDSN [plasma membrane] (Homo sapiens)
Cornified envelope [plasma membrane] (Homo sapiens)
Early cornified envelope [plasma membrane] (Homo sapiens)
FLG-Keratin filament network [plasma membrane] (Homo sapiens)
FLG(?-?):Keratin tonofilament:Desmosome [plasma membrane] (Homo sapiens)
Keratin tonofilament:Desmosome [plasma membrane] (Homo sapiens)
Keratin tonofilament [cytosol] (Homo sapiens)
Keratin filament [cytosol] (Homo sapiens)
Keratin filament units [cytosol] (Homo sapiens)
Keratin tetramer [cytosol] (Homo sapiens)
Keratin heterodimer [cytosol] (Homo sapiens)
Keratin type I [cytosol] (Homo sapiens)
Keratin type I, hair specific [cytosol] (Homo sapiens)
KRT40 [cytosol] (Homo sapiens)
Keratin unit length filament [cytosol] (Homo sapiens)
Keratin tetramer [cytosol] (Homo sapiens)
Keratin heterodimer [cytosol] (Homo sapiens)
Keratin type I [cytosol] (Homo sapiens)
Keratin type I, hair specific [cytosol] (Homo sapiens)
KRT40 [cytosol] (Homo sapiens)
Mature cornified envelope [plasma membrane] (Homo sapiens)
No FGN-cornified envelope:CDSN [plasma membrane] (Homo sapiens)
No FGN-Cornified envelope [plasma membrane] (Homo sapiens)
No FGN-late cornified envelope [plasma membrane] (Homo sapiens)
Keratin tonofilament:Desmosome network [plasma membrane] (Homo sapiens)
Keratin tonofilament:Desmosome [plasma membrane] (Homo sapiens)
Keratin tonofilament [cytosol] (Homo sapiens)
Keratin filament [cytosol] (Homo sapiens)
Keratin filament units [cytosol] (Homo sapiens)
Keratin tetramer [cytosol] (Homo sapiens)
Keratin heterodimer [cytosol] (Homo sapiens)
Keratin type I [cytosol] (Homo sapiens)
Keratin type I, hair specific [cytosol] (Homo sapiens)
KRT40 [cytosol] (Homo sapiens)
Keratin unit length filament [cytosol] (Homo sapiens)
Keratin tetramer [cytosol] (Homo sapiens)
Keratin heterodimer [cytosol] (Homo sapiens)
Keratin type I [cytosol] (Homo sapiens)
Keratin type I, hair specific [cytosol] (Homo sapiens)
KRT40 [cytosol] (Homo sapiens)
CDSN binds the cornified envelope (Homo sapiens)
Cornified envelope [plasma membrane] (Homo sapiens)
Early cornified envelope [plasma membrane] (Homo sapiens)
FLG-Keratin filament network [plasma membrane] (Homo sapiens)
FLG(?-?):Keratin tonofilament:Desmosome [plasma membrane] (Homo sapiens)
Keratin tonofilament:Desmosome [plasma membrane] (Homo sapiens)
Keratin tonofilament [cytosol] (Homo sapiens)
Keratin filament [cytosol] (Homo sapiens)
Keratin filament units [cytosol] (Homo sapiens)
Keratin tetramer [cytosol] (Homo sapiens)
Keratin heterodimer [cytosol] (Homo sapiens)
Keratin type I [cytosol] (Homo sapiens)
Keratin type I, hair specific [cytosol] (Homo sapiens)
KRT40 [cytosol] (Homo sapiens)
Keratin unit length filament [cytosol] (Homo sapiens)
Keratin tetramer [cytosol] (Homo sapiens)
Keratin heterodimer [cytosol] (Homo sapiens)
Keratin type I [cytosol] (Homo sapiens)
Keratin type I, hair specific [cytosol] (Homo sapiens)
KRT40 [cytosol] (Homo sapiens)
Cornified envelope:CDSN [plasma membrane] (Homo sapiens)
Cornified envelope [plasma membrane] (Homo sapiens)
Early cornified envelope [plasma membrane] (Homo sapiens)
FLG-Keratin filament network [plasma membrane] (Homo sapiens)
FLG(?-?):Keratin tonofilament:Desmosome [plasma membrane] (Homo sapiens)
Keratin tonofilament:Desmosome [plasma membrane] (Homo sapiens)
Keratin tonofilament [cytosol] (Homo sapiens)
Keratin filament [cytosol] (Homo sapiens)
Keratin filament units [cytosol] (Homo sapiens)
Keratin tetramer [cytosol] (Homo sapiens)
Keratin heterodimer [cytosol] (Homo sapiens)
Keratin type I [cytosol] (Homo sapiens)
Keratin type I, hair specific [cytosol] (Homo sapiens)
KRT40 [cytosol] (Homo sapiens)
Keratin unit length filament [cytosol] (Homo sapiens)
Keratin tetramer [cytosol] (Homo sapiens)
Keratin heterodimer [cytosol] (Homo sapiens)
Keratin type I [cytosol] (Homo sapiens)
Keratin type I, hair specific [cytosol] (Homo sapiens)
KRT40 [cytosol] (Homo sapiens)
Filaggrin binds Keratin tonofilament:Desmosome (Homo sapiens)
FLG(?-?):Keratin tonofilament:Desmosome [plasma membrane] (Homo sapiens)
Keratin tonofilament:Desmosome [plasma membrane] (Homo sapiens)
Keratin tonofilament [cytosol] (Homo sapiens)
Keratin filament [cytosol] (Homo sapiens)
Keratin filament units [cytosol] (Homo sapiens)
Keratin tetramer [cytosol] (Homo sapiens)
Keratin heterodimer [cytosol] (Homo sapiens)
Keratin type I [cytosol] (Homo sapiens)
Keratin type I, hair specific [cytosol] (Homo sapiens)
KRT40 [cytosol] (Homo sapiens)
Keratin unit length filament [cytosol] (Homo sapiens)
Keratin tetramer [cytosol] (Homo sapiens)
Keratin heterodimer [cytosol] (Homo sapiens)
Keratin type I [cytosol] (Homo sapiens)
Keratin type I, hair specific [cytosol] (Homo sapiens)
KRT40 [cytosol] (Homo sapiens)
Keratin tonofilament:Desmosome [plasma membrane] (Homo sapiens)
Keratin tonofilament [cytosol] (Homo sapiens)
Keratin filament [cytosol] (Homo sapiens)
Keratin filament units [cytosol] (Homo sapiens)
Keratin tetramer [cytosol] (Homo sapiens)
Keratin heterodimer [cytosol] (Homo sapiens)
Keratin type I [cytosol] (Homo sapiens)
Keratin type I, hair specific [cytosol] (Homo sapiens)
KRT40 [cytosol] (Homo sapiens)
Keratin unit length filament [cytosol] (Homo sapiens)
Keratin tetramer [cytosol] (Homo sapiens)
Keratin heterodimer [cytosol] (Homo sapiens)
Keratin type I [cytosol] (Homo sapiens)
Keratin type I, hair specific [cytosol] (Homo sapiens)
KRT40 [cytosol] (Homo sapiens)
Fillagrin and keratin intermediate filaments polymerise forming a network (Homo sapiens)
FLG(?-?):Keratin tonofilament:Desmosome [plasma membrane] (Homo sapiens)
Keratin tonofilament:Desmosome [plasma membrane] (Homo sapiens)
Keratin tonofilament [cytosol] (Homo sapiens)
Keratin filament [cytosol] (Homo sapiens)
Keratin filament units [cytosol] (Homo sapiens)
Keratin tetramer [cytosol] (Homo sapiens)
Keratin heterodimer [cytosol] (Homo sapiens)
Keratin type I [cytosol] (Homo sapiens)
Keratin type I, hair specific [cytosol] (Homo sapiens)
KRT40 [cytosol] (Homo sapiens)
Keratin unit length filament [cytosol] (Homo sapiens)
Keratin tetramer [cytosol] (Homo sapiens)
Keratin heterodimer [cytosol] (Homo sapiens)
Keratin type I [cytosol] (Homo sapiens)
Keratin type I, hair specific [cytosol] (Homo sapiens)
KRT40 [cytosol] (Homo sapiens)
FLG-Keratin filament network [plasma membrane] (Homo sapiens)
FLG(?-?):Keratin tonofilament:Desmosome [plasma membrane] (Homo sapiens)
Keratin tonofilament:Desmosome [plasma membrane] (Homo sapiens)
Keratin tonofilament [cytosol] (Homo sapiens)
Keratin filament [cytosol] (Homo sapiens)
Keratin filament units [cytosol] (Homo sapiens)
Keratin tetramer [cytosol] (Homo sapiens)
Keratin heterodimer [cytosol] (Homo sapiens)
Keratin type I [cytosol] (Homo sapiens)
Keratin type I, hair specific [cytosol] (Homo sapiens)
KRT40 [cytosol] (Homo sapiens)
Keratin unit length filament [cytosol] (Homo sapiens)
Keratin tetramer [cytosol] (Homo sapiens)
Keratin heterodimer [cytosol] (Homo sapiens)
Keratin type I [cytosol] (Homo sapiens)
Keratin type I, hair specific [cytosol] (Homo sapiens)
KRT40 [cytosol] (Homo sapiens)
Lamellar bodies bind the early cornified envelope (Homo sapiens)
Cornified envelope [plasma membrane] (Homo sapiens)
Early cornified envelope [plasma membrane] (Homo sapiens)
FLG-Keratin filament network [plasma membrane] (Homo sapiens)
FLG(?-?):Keratin tonofilament:Desmosome [plasma membrane] (Homo sapiens)
Keratin tonofilament:Desmosome [plasma membrane] (Homo sapiens)
Keratin tonofilament [cytosol] (Homo sapiens)
Keratin filament [cytosol] (Homo sapiens)
Keratin filament units [cytosol] (Homo sapiens)
Keratin tetramer [cytosol] (Homo sapiens)
Keratin heterodimer [cytosol] (Homo sapiens)
Keratin type I [cytosol] (Homo sapiens)
Keratin type I, hair specific [cytosol] (Homo sapiens)
KRT40 [cytosol] (Homo sapiens)
Keratin unit length filament [cytosol] (Homo sapiens)
Keratin tetramer [cytosol] (Homo sapiens)
Keratin heterodimer [cytosol] (Homo sapiens)
Keratin type I [cytosol] (Homo sapiens)
Keratin type I, hair specific [cytosol] (Homo sapiens)
KRT40 [cytosol] (Homo sapiens)
Early cornified envelope [plasma membrane] (Homo sapiens)
FLG-Keratin filament network [plasma membrane] (Homo sapiens)
FLG(?-?):Keratin tonofilament:Desmosome [plasma membrane] (Homo sapiens)
Keratin tonofilament:Desmosome [plasma membrane] (Homo sapiens)
Keratin tonofilament [cytosol] (Homo sapiens)
Keratin filament [cytosol] (Homo sapiens)
Keratin filament units [cytosol] (Homo sapiens)
Keratin tetramer [cytosol] (Homo sapiens)
Keratin heterodimer [cytosol] (Homo sapiens)
Keratin type I [cytosol] (Homo sapiens)
Keratin type I, hair specific [cytosol] (Homo sapiens)
KRT40 [cytosol] (Homo sapiens)
Keratin unit length filament [cytosol] (Homo sapiens)
Keratin tetramer [cytosol] (Homo sapiens)
Keratin heterodimer [cytosol] (Homo sapiens)
Keratin type I [cytosol] (Homo sapiens)
Keratin type I, hair specific [cytosol] (Homo sapiens)
KRT40 [cytosol] (Homo sapiens)
Late envelope proteins bind cornified envelope:CDSN (Homo sapiens)
Cornified envelope:CDSN [plasma membrane] (Homo sapiens)
Cornified envelope [plasma membrane] (Homo sapiens)
Early cornified envelope [plasma membrane] (Homo sapiens)
FLG-Keratin filament network [plasma membrane] (Homo sapiens)
FLG(?-?):Keratin tonofilament:Desmosome [plasma membrane] (Homo sapiens)
Keratin tonofilament:Desmosome [plasma membrane] (Homo sapiens)
Keratin tonofilament [cytosol] (Homo sapiens)
Keratin filament [cytosol] (Homo sapiens)
Keratin filament units [cytosol] (Homo sapiens)
Keratin tetramer [cytosol] (Homo sapiens)
Keratin heterodimer [cytosol] (Homo sapiens)
Keratin type I [cytosol] (Homo sapiens)
Keratin type I, hair specific [cytosol] (Homo sapiens)
KRT40 [cytosol] (Homo sapiens)
Keratin unit length filament [cytosol] (Homo sapiens)
Keratin tetramer [cytosol] (Homo sapiens)
Keratin heterodimer [cytosol] (Homo sapiens)
Keratin type I [cytosol] (Homo sapiens)
Keratin type I, hair specific [cytosol] (Homo sapiens)
KRT40 [cytosol] (Homo sapiens)
Late cornified envelope [plasma membrane] (Homo sapiens)
Cornified envelope:CDSN [plasma membrane] (Homo sapiens)
Cornified envelope [plasma membrane] (Homo sapiens)
Early cornified envelope [plasma membrane] (Homo sapiens)
FLG-Keratin filament network [plasma membrane] (Homo sapiens)
FLG(?-?):Keratin tonofilament:Desmosome [plasma membrane] (Homo sapiens)
Keratin tonofilament:Desmosome [plasma membrane] (Homo sapiens)
Keratin tonofilament [cytosol] (Homo sapiens)
Keratin filament [cytosol] (Homo sapiens)
Keratin filament units [cytosol] (Homo sapiens)
Keratin tetramer [cytosol] (Homo sapiens)
Keratin heterodimer [cytosol] (Homo sapiens)
Keratin type I [cytosol] (Homo sapiens)
Keratin type I, hair specific [cytosol] (Homo sapiens)
KRT40 [cytosol] (Homo sapiens)
Keratin unit length filament [cytosol] (Homo sapiens)
Keratin tetramer [cytosol] (Homo sapiens)
Keratin heterodimer [cytosol] (Homo sapiens)
Keratin type I [cytosol] (Homo sapiens)
Keratin type I, hair specific [cytosol] (Homo sapiens)
KRT40 [cytosol] (Homo sapiens)
Plasma membrane resorption (Homo sapiens)
Mature cornified envelope [cornified envelope] (Homo sapiens)
No FGN-cornified envelope:CDSN [cornified envelope] (Homo sapiens)
No FGN-Cornified envelope [cornified envelope] (Homo sapiens)
No FGN-early cornified envelope [cornified envelope] (Homo sapiens)
Keratin tonofilament:Desmosome network [cornified envelope] (Homo sapiens)
Keratin tonofilament:Desmosome [cornified envelope] (Homo sapiens)
Keratin tonofilament [cytosol] (Homo sapiens)
Keratin filament [cytosol] (Homo sapiens)
Keratin filament units [cytosol] (Homo sapiens)
Keratin tetramer [cytosol] (Homo sapiens)
Keratin heterodimer [cytosol] (Homo sapiens)
Keratin type I [cytosol] (Homo sapiens)
Keratin type I, hair specific [cytosol] (Homo sapiens)
KRT40 [cytosol] (Homo sapiens)
Keratin unit length filament [cytosol] (Homo sapiens)
Keratin tetramer [cytosol] (Homo sapiens)
Keratin heterodimer [cytosol] (Homo sapiens)
Keratin type I [cytosol] (Homo sapiens)
Keratin type I, hair specific [cytosol] (Homo sapiens)
KRT40 [cytosol] (Homo sapiens)
Mature cornified envelope [plasma membrane] (Homo sapiens)
No FGN-cornified envelope:CDSN [plasma membrane] (Homo sapiens)
No FGN-Cornified envelope [plasma membrane] (Homo sapiens)
No FGN-late cornified envelope [plasma membrane] (Homo sapiens)
Keratin tonofilament:Desmosome network [plasma membrane] (Homo sapiens)
Keratin tonofilament:Desmosome [plasma membrane] (Homo sapiens)
Keratin tonofilament [cytosol] (Homo sapiens)
Keratin filament [cytosol] (Homo sapiens)
Keratin filament units [cytosol] (Homo sapiens)
Keratin tetramer [cytosol] (Homo sapiens)
Keratin heterodimer [cytosol] (Homo sapiens)
Keratin type I [cytosol] (Homo sapiens)
Keratin type I, hair specific [cytosol] (Homo sapiens)
KRT40 [cytosol] (Homo sapiens)
Keratin unit length filament [cytosol] (Homo sapiens)
Keratin tetramer [cytosol] (Homo sapiens)
Keratin heterodimer [cytosol] (Homo sapiens)
Keratin type I [cytosol] (Homo sapiens)
Keratin type I, hair specific [cytosol] (Homo sapiens)
KRT40 [cytosol] (Homo sapiens)
Reinforcement of the Cornified Envelope (Homo sapiens)
Early cornified envelope [plasma membrane] (Homo sapiens)
FLG-Keratin filament network [plasma membrane] (Homo sapiens)
FLG(?-?):Keratin tonofilament:Desmosome [plasma membrane] (Homo sapiens)
Keratin tonofilament:Desmosome [plasma membrane] (Homo sapiens)
Keratin tonofilament [cytosol] (Homo sapiens)
Keratin filament [cytosol] (Homo sapiens)
Keratin filament units [cytosol] (Homo sapiens)
Keratin tetramer [cytosol] (Homo sapiens)
Keratin heterodimer [cytosol] (Homo sapiens)
Keratin type I [cytosol] (Homo sapiens)
Keratin type I, hair specific [cytosol] (Homo sapiens)
KRT40 [cytosol] (Homo sapiens)
Keratin unit length filament [cytosol] (Homo sapiens)
Keratin tetramer [cytosol] (Homo sapiens)
Keratin heterodimer [cytosol] (Homo sapiens)
Keratin type I [cytosol] (Homo sapiens)
Keratin type I, hair specific [cytosol] (Homo sapiens)
KRT40 [cytosol] (Homo sapiens)
FLG-Keratin filament network [plasma membrane] (Homo sapiens)
FLG(?-?):Keratin tonofilament:Desmosome [plasma membrane] (Homo sapiens)
Keratin tonofilament:Desmosome [plasma membrane] (Homo sapiens)
Keratin tonofilament [cytosol] (Homo sapiens)
Keratin filament [cytosol] (Homo sapiens)
Keratin filament units [cytosol] (Homo sapiens)
Keratin tetramer [cytosol] (Homo sapiens)
Keratin heterodimer [cytosol] (Homo sapiens)
Keratin type I [cytosol] (Homo sapiens)
Keratin type I, hair specific [cytosol] (Homo sapiens)
KRT40 [cytosol] (Homo sapiens)
Keratin unit length filament [cytosol] (Homo sapiens)
Keratin tetramer [cytosol] (Homo sapiens)
Keratin heterodimer [cytosol] (Homo sapiens)
Keratin type I [cytosol] (Homo sapiens)
Keratin type I, hair specific [cytosol] (Homo sapiens)
KRT40 [cytosol] (Homo sapiens)
Formation of tonofilament bundles (Homo sapiens)
Keratin filament [cytosol] (Homo sapiens)
Keratin filament units [cytosol] (Homo sapiens)
Keratin tetramer [cytosol] (Homo sapiens)
Keratin heterodimer [cytosol] (Homo sapiens)
Keratin type I [cytosol] (Homo sapiens)
Keratin type I, hair specific [cytosol] (Homo sapiens)
KRT40 [cytosol] (Homo sapiens)
Keratin unit length filament [cytosol] (Homo sapiens)
Keratin tetramer [cytosol] (Homo sapiens)
Keratin heterodimer [cytosol] (Homo sapiens)
Keratin type I [cytosol] (Homo sapiens)
Keratin type I, hair specific [cytosol] (Homo sapiens)
KRT40 [cytosol] (Homo sapiens)
Keratin tonofilament [cytosol] (Homo sapiens)
Keratin filament [cytosol] (Homo sapiens)
Keratin filament units [cytosol] (Homo sapiens)
Keratin tetramer [cytosol] (Homo sapiens)
Keratin heterodimer [cytosol] (Homo sapiens)
Keratin type I [cytosol] (Homo sapiens)
Keratin type I, hair specific [cytosol] (Homo sapiens)
KRT40 [cytosol] (Homo sapiens)
Keratin unit length filament [cytosol] (Homo sapiens)
Keratin tetramer [cytosol] (Homo sapiens)
Keratin heterodimer [cytosol] (Homo sapiens)
Keratin type I [cytosol] (Homo sapiens)
Keratin type I, hair specific [cytosol] (Homo sapiens)
KRT40 [cytosol] (Homo sapiens)
Keratin filament formation (Homo sapiens)
Keratin filament [cytosol] (Homo sapiens)
Keratin filament units [cytosol] (Homo sapiens)
Keratin tetramer [cytosol] (Homo sapiens)
Keratin heterodimer [cytosol] (Homo sapiens)
Keratin type I [cytosol] (Homo sapiens)
Keratin type I, hair specific [cytosol] (Homo sapiens)
KRT40 [cytosol] (Homo sapiens)
Keratin unit length filament [cytosol] (Homo sapiens)
Keratin tetramer [cytosol] (Homo sapiens)
Keratin heterodimer [cytosol] (Homo sapiens)
Keratin type I [cytosol] (Homo sapiens)
Keratin type I, hair specific [cytosol] (Homo sapiens)
KRT40 [cytosol] (Homo sapiens)
Keratin filament units [cytosol] (Homo sapiens)
Keratin tetramer [cytosol] (Homo sapiens)
Keratin heterodimer [cytosol] (Homo sapiens)
Keratin type I [cytosol] (Homo sapiens)
Keratin type I, hair specific [cytosol] (Homo sapiens)
KRT40 [cytosol] (Homo sapiens)
Keratin unit length filament [cytosol] (Homo sapiens)
Keratin tetramer [cytosol] (Homo sapiens)
Keratin heterodimer [cytosol] (Homo sapiens)
Keratin type I [cytosol] (Homo sapiens)
Keratin type I, hair specific [cytosol] (Homo sapiens)
KRT40 [cytosol] (Homo sapiens)
Keratin filaments bind cell-cell adhesion complexes (Homo sapiens)
Keratin tonofilament [cytosol] (Homo sapiens)
Keratin filament [cytosol] (Homo sapiens)
Keratin filament units [cytosol] (Homo sapiens)
Keratin tetramer [cytosol] (Homo sapiens)
Keratin heterodimer [cytosol] (Homo sapiens)
Keratin type I [cytosol] (Homo sapiens)
Keratin type I, hair specific [cytosol] (Homo sapiens)
KRT40 [cytosol] (Homo sapiens)
Keratin unit length filament [cytosol] (Homo sapiens)
Keratin tetramer [cytosol] (Homo sapiens)
Keratin heterodimer [cytosol] (Homo sapiens)
Keratin type I [cytosol] (Homo sapiens)
Keratin type I, hair specific [cytosol] (Homo sapiens)
KRT40 [cytosol] (Homo sapiens)
Keratin tonofilament:Desmosome [plasma membrane] (Homo sapiens)
Keratin tonofilament [cytosol] (Homo sapiens)
Keratin filament [cytosol] (Homo sapiens)
Keratin filament units [cytosol] (Homo sapiens)
Keratin tetramer [cytosol] (Homo sapiens)
Keratin heterodimer [cytosol] (Homo sapiens)
Keratin type I [cytosol] (Homo sapiens)
Keratin type I, hair specific [cytosol] (Homo sapiens)
KRT40 [cytosol] (Homo sapiens)
Keratin unit length filament [cytosol] (Homo sapiens)
Keratin tetramer [cytosol] (Homo sapiens)
Keratin heterodimer [cytosol] (Homo sapiens)
Keratin type I [cytosol] (Homo sapiens)
Keratin type I, hair specific [cytosol] (Homo sapiens)
KRT40 [cytosol] (Homo sapiens)
Keratin tetramers bind to form unit length filaments (Homo sapiens)
Keratin tetramer [cytosol] (Homo sapiens)
Keratin heterodimer [cytosol] (Homo sapiens)
Keratin type I [cytosol] (Homo sapiens)
Keratin type I, hair specific [cytosol] (Homo sapiens)
KRT40 [cytosol] (Homo sapiens)
Keratin unit length filament [cytosol] (Homo sapiens)
Keratin tetramer [cytosol] (Homo sapiens)
Keratin heterodimer [cytosol] (Homo sapiens)
Keratin type I [cytosol] (Homo sapiens)
Keratin type I, hair specific [cytosol] (Homo sapiens)
KRT40 [cytosol] (Homo sapiens)
Keratin type I binds keratin type II (Homo sapiens)
Keratin heterodimer [cytosol] (Homo sapiens)
Keratin type I [cytosol] (Homo sapiens)
Keratin type I, hair specific [cytosol] (Homo sapiens)
KRT40 [cytosol] (Homo sapiens)
Keratin type I [cytosol] (Homo sapiens)
Keratin type I, hair specific [cytosol] (Homo sapiens)
KRT40 [cytosol] (Homo sapiens)
Keratin type I/type II heterodimers form tetramers (Homo sapiens)
Keratin heterodimer [cytosol] (Homo sapiens)
Keratin type I [cytosol] (Homo sapiens)
Keratin type I, hair specific [cytosol] (Homo sapiens)
KRT40 [cytosol] (Homo sapiens)
Keratin tetramer [cytosol] (Homo sapiens)
Keratin heterodimer [cytosol] (Homo sapiens)
Keratin type I [cytosol] (Homo sapiens)
Keratin type I, hair specific [cytosol] (Homo sapiens)
KRT40 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q6A162 KRT40
Gene Names
KRT40, KA36
Chain
chain:1-431
Reference Genes
BioGPS Gene:125115 KRT40
COSMIC (genes):KRT40 KRT40
CTD Gene:125115 KRT40
dbSNP Gene:125115 KRT40
ENSEMBL:ENSG00000204889 KRT40
ENSEMBL:ENSG00000204889.11 KRT40
ENSEMBL:ENSG00000262845.7 KRT40
HGNC:26707 KRT40
KEGG Gene (Homo sapiens):125115 KRT40
Monarch:125115 KRT40
NCBI Gene:125115 KRT40
OMIM:616679 KRT40
UCSC:Q6A162 KRT40
Reference Transcript
RefSeq:NM_182497.3 KRT40
Other Identifiers
0005360017
11738403_at
11738404_s_at
125115
1562628_PM_at
1562628_at
1562629_PM_a_at
1562629_a_at
16844533
3756631
3756633
3756634
3756636
3756637
3756641
3756643
3756644
3756645
3756646
3756647
3756648
8015152
8019604
A_33_P3310894
GE477047
GO:0005198
GO:0005515
GO:0005622
GO:0005737
GO:0005829
GO:0005856
GO:0005882
GO:0007010
GO:0030154
GO:0030855
GO:0043226
GO:0045109
GO:0048856
HMNXSV003005746
Hs2.146635.1.S1_3p_at
ILMN_1658563
ILMN_1663578
ILMN_2201768
PH_hs_0031822
PH_hs_0040615
TC17001475.hg
Participates
as a member of
Keratin type I, hair specific [cytosol] (Homo sapiens)
Inferred To
Homologues of KRT40 [cytosol]
(Danio rerio)
si:dkeyp-113d7.7 [cytosol]
(Danio rerio)
DKEY-90G20.1 [cytosol]
(Danio rerio)
KRT40 [cytosol]
(Bos taurus)
KRT40 [cytosol]
(Canis familiaris)
KRT40 [cytosol]
(Danio rerio)
KRT40 [cytosol]
(Sus scrofa)
krt17 [cytosol]
(Danio rerio)
krt34 [cytosol]
(Xenopus tropicalis)
Krt40 [cytosol]
(Mus musculus)
Krt40 [cytosol]
(Rattus norvegicus)
cki [cytosol]
(Danio rerio)
Cross References
RefSeq
NP_872303.2
OpenTargets
ENSG00000204889
HPA
ENSG00000204889-KRT40
GeneCards
Q6A162
Ensembl
ENSG00000262845
,
ENST00000610983
,
ENSP00000506768
,
ENST00000377755
,
ENSP00000381500
,
ENSP00000479080
,
ENST00000684280
,
ENSP00000366984
,
ENST00000576967
,
ENSG00000204889
,
ENST00000398486
,
ENSP00000459621
PRO
Q6A162
Pharos - Targets
Q6A162
Interactors (58)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:O14964 HGS
2
HGS [cytosol]
(R-HSA-182954)
HGS [phagocytic vesicle lumen]
(R-HSA-9635660)
0.718
6
UniProt:Q96BZ8 LENG1
1
LENG1 [nucleoplasm]
(R-HSA-9769590)
0.718
6
UniProt:Q92608 DOCK2
3
DOCK2 [specific granule lumen]
(R-HSA-6799558)
DOCK2 [extracellular region]
(R-HSA-6806310)
DOCK2 [cytosol]
(R-HSA-200938)
0.718
6
UniProt:P99999 CYCS
4
CYCS [cytosol]
(R-HSA-53259)
CYCS [mitochondrial intermembrane space]
(R-HSA-114244)
CYCS [mitochondrial inner membrane]
(R-HSA-352608)
AcK-CYCS [mitochondrial intermembrane space]
(R-HSA-5688308)
0.718
6
UniProt:O75604 USP2
2
USP2 [cytosol]
(R-HSA-5212661)
USP2 [nucleoplasm]
(R-HSA-5689946)
0.718
6
UniProt:Q15561 TEAD4
1
TEAD4 [nucleoplasm]
(R-HSA-2032780)
0.718
6
UniProt:P40222 TXLNA
1
TXLNA [cytosol]
(R-HSA-449124)
0.718
6
UniProt:O95363 FARS2
1
FARS2(1-?) [mitochondrial matrix]
(R-HSA-379565)
0.718
6
UniProt:Q13895 BYSL
2
BYSL [nucleoplasm]
(R-HSA-6791526)
BYSL [cytosol]
(R-HSA-6791518)
0.718
8
UniProt:P19544 WT1
1
WT1 [nucleoplasm]
(R-HSA-452420)
0.666
4
UniProt:Q13330 MTA1
2
MTA1 [nucleoplasm]
(R-HSA-3465550)
polySUMO2,3-K509-MTA1 [nucleoplasm]
(R-HSA-3465537)
0.666
4
UniProt:O95863 SNAI1
1
SNAI1 [nucleoplasm]
(R-HSA-2980903)
0.666
4
UniProt:O60341 KDM1A
1
KDM1A [nucleoplasm]
(R-HSA-996769)
0.556
3
UniProt:P43353 ALDH3B1
3
ALDH3B1 [secretory granule membrane]
(R-HSA-6801023)
ALDH3B1 [plasma membrane]
(R-HSA-5696096)
ALDH3B1 [specific granule membrane]
(R-HSA-6799510)
0.556
3
UniProt:Q96QF0 RAB3IP
1
RAB3IP [cytosol]
(R-HSA-5617610)
0.556
3
UniProt:P08631 HCK
2
p-HCK [cytosol]
(R-HSA-9676060)
HCK [cytosol]
(R-HSA-167708)
0.556
3
UniProt:Q92993 KAT5
1
KAT5 [nucleoplasm]
(R-HSA-3321979)
0.556
3
UniProt:Q9NX63 CHCHD3
3
CHCHD3 (MIC19) [mitochondrial inner membrane]
(R-HSA-8949583)
CHCHD3 [mitochondrial intermembrane space]
(R-HSA-8874907)
4xHC-CHCHD3 [mitochondrial intermembrane space]
(R-HSA-8874910)
0.556
3
UniProt:Q9H257 CARD9
3
CARD9 [cytosol]
(R-HSA-561194)
CARD9 [plasma membrane]
(R-HSA-5607662)
p-T231-CARD9 [plasma membrane]
(R-HSA-5607623)
0.556
3
UniProt:Q49AN0 CRY2
4
p-S-CRY2 [cytosol]
(R-HSA-400305)
p-S-CRY2 [nucleoplasm]
(R-HSA-400328)
CRY2 [cytosol]
(R-HSA-400255)
Ub-p-S-CRY2 [nucleoplasm]
(R-HSA-517935)
0.556
3
UniProt:Q2TBE0 CWF19L2
1
CWF19L2 [nucleoplasm]
(R-HSA-9770846)
0.556
3
UniProt:Q13526 PIN1
2
PIN1 [cytosol]
(R-HSA-9626823)
PIN1 [nucleoplasm]
(R-HSA-936016)
0.556
3
UniProt:P10809 HSPD1
6
HSPD1(1-573) [cytosol]
(R-HSA-1267989)
HSPD1(1-573) [mitochondrial intermembrane space]
(R-HSA-1267963)
HSPD1(1-26) [mitochondrial matrix]
(R-HSA-8986171)
HSPD1(1-573) [mitochondrial inner membrane]
(R-HSA-1299442)
HSPD1 [mitochondrial inner membrane]
(R-HSA-1299455)
HSPD1 [mitochondrial matrix]
(R-HSA-1299448)
0.556
3
UniProt:Q96HC4 PDLIM5
1
PDLIM5 [cytosol]
(R-HSA-6794246)
0.556
3
UniProt:O95391 SLU7
1
hSLU7 [nucleoplasm]
(R-HSA-72073)
0.556
3
UniProt:Q9UIL1 SCOC
1
SCOC [cytosol]
(R-HSA-6813911)
0.556
3
UniProt:Q9UBU9 NXF1
2
NXF1 [cytosol]
(R-HSA-156481)
NXF1 [nucleoplasm]
(R-HSA-111690)
0.556
3
UniProt:Q13875 MOBP
1
MOBP [cytosol]
(R-HSA-9022884)
0.556
3
UniProt:Q99633 PRPF18
1
PRPF18 [nucleoplasm]
(R-HSA-5688093)
0.556
3
UniProt:P55040 GEM
1
GEM [plasma membrane]
(R-HSA-9769962)
0.556
3
UniProt:Q9BZF9 UACA
1
UACA [cytosol]
(R-HSA-6804636)
0.556
3
UniProt:Q92835 INPP5D
2
p-Y-INPP5D [cytosol]
(R-HSA-9680730)
INPP5D [cytosol]
(R-HSA-197940)
0.556
3
UniProt:Q9H2F3 HSD3B7
1
HSD3B7 [endoplasmic reticulum membrane]
(R-HSA-193441)
0.556
3
UniProt:Q99757 TXN2
2
TXN2 [mitochondrial matrix]
(R-HSA-3323048)
2xHC-TXN2 [mitochondrial matrix]
(R-HSA-3323059)
0.556
3
UniProt:P63000 RAC1
6
RAC1 [secretory granule membrane]
(R-HSA-6804770)
RAC1 [ficolin-1-rich granule membrane]
(R-HSA-6804802)
GGC-PalmC-RAC1 [plasma membrane]
(R-HSA-2316446)
RAC1 [endoplasmic reticulum membrane]
(R-HSA-5672076)
RAC1 [cytosol]
(R-HSA-442615)
RAC1 [plasma membrane]
(R-HSA-351141)
0.556
3
UniProt:Q9H1K1 ISCU
1
ISCU [cytosol]
(R-HSA-9771680)
0.556
3
UniProt:P52292 KPNA2
2
KPNA2 [nucleoplasm]
(R-HSA-206045)
KPNA2 [cytosol]
(R-HSA-205976)
0.556
3
UniProt:Q96E11 MRRF
1
MRRF [mitochondrial matrix]
(R-HSA-5419265)
0.556
3
UniProt:Q99728 BARD1
13
BARD1 G623E [nucleoplasm]
(R-HSA-9699135)
BARD1 C71Y [nucleoplasm]
(R-HSA-9700808)
BARD1 C53W [nucleoplasm]
(R-HSA-9700807)
BARD1 G623W [nucleoplasm]
(R-HSA-9699148)
BARD1 W34R [nucleoplasm]
(R-HSA-9699166)
BARD1 H68Y [nucleoplasm]
(R-HSA-9699151)
BARD1 L44R [nucleoplasm]
(R-HSA-9699126)
BARD1 C50G [nucleoplasm]
(R-HSA-9699137)
K6PolyUb,p-T714,T734-BARD1 [nucleoplasm]
(R-HSA-9707286)
p-T714,T734-BARD1 [nucleoplasm]
(R-HSA-5659846)
K6PolyUb-BARD1 [nucleoplasm]
(R-HSA-9701024)
BARD1 [nucleoplasm]
(R-HSA-5659775)
BARD1 C83G [nucleoplasm]
(R-HSA-9699139)
0.556
3
UniProt:O60573 EIF4E2
1
EIF4E2 [cytosol]
(R-HSA-1678822)
0.556
3
UniProt:Q9UBX3 SLC25A10
1
SLC25A10 [mitochondrial inner membrane]
(R-HSA-372848)
0.556
3
UniProt:P23769 GATA2
1
GATA2 [nucleoplasm]
(R-HSA-996735)
0.556
3
UniProt:P26441 CNTF
1
CNTF [extracellular region]
(R-HSA-5696441)
0.556
3
UniProt:P48023 FASLG
1
FASLG(1-281) [extracellular region]
(R-HSA-66212)
0.556
3
UniProt:P51959 CCNG1
1
CCNG1 [nucleoplasm]
(R-HSA-6792489)
0.556
3
UniProt:Q9UBK9 UXT
1
UXT [nucleoplasm]
(R-HSA-9007484)
0.556
3
UniProt:P55081 MFAP1
1
MFAP1 [nucleoplasm]
(R-HSA-2396419)
0.556
3
UniProt:Q08117 TLE5
1
AES [nucleoplasm]
(R-HSA-4648963)
0.556
3
UniProt:O15169 AXIN1
11
AXIN1 L396M [cytosol]
(R-HSA-5251503)
AXIN1 Y346* [cytosol]
(R-HSA-4839753)
AXIN1 E406* [cytosol]
(R-HSA-5251500)
AXIN1 W247* [cytosol]
(R-HSA-5251512)
AXIN1 P354L [cytosol]
(R-HSA-5251511)
AXIN1 P255S [cytosol]
(R-HSA-5251505)
ub-AXIN1 [cytosol]
(R-HSA-4641133)
Ub-RibC-AXIN1 [cytosol]
(R-HSA-3640864)
AXIN1 [cytosol]
(R-HSA-195249)
p-T519,S524,S531-AXIN1 [cytosol]
(R-HSA-206040)
RibC-AXIN1 [cytosol]
(R-HSA-3640841)
0.556
3
UniProt:Q9UBR2 CTSZ
9
(Glc)3(GlcNAc)2(Man)9-CTSZ [endoplasmic reticulum lumen]
(R-HSA-5689431)
(Glc)3(GlcNAc)2(Man)9-CTSZ [COPII-coated ER to Golgi transport vesicle]
(R-HSA-5689727)
(Glc)3(GlcNAc)2(Man)9-CTSZ [endoplasmic reticulum-Golgi intermediate compartment membrane]
(R-HSA-5689730)
CTSZ [ficolin-1-rich granule lumen]
(R-HSA-6801318)
CTSZ [extracellular region]
(R-HSA-6801569)
CTSZ [specific granule lumen]
(R-HSA-6801304)
CTSZ [plasma membrane]
(R-HSA-2022345)
CTSZ [lysosomal lumen]
(R-HSA-429814)
CTSZ [Golgi lumen]
(R-HSA-434321)
0.556
3
UniProt:Q4G176 ACSF3
1
ACSF3 [mitochondrial matrix]
(R-HSA-5696011)
0.556
3
UniProt:Q13573 SNW1
1
SNW1 [nucleoplasm]
(R-HSA-351663)
0.556
3
UniProt:O43602 DCX
1
DCX [cytosol]
(R-HSA-430060)
0.556
3
UniProt:Q96NC0 ZMAT2
1
ZMAT2 [nucleoplasm]
(R-HSA-9770248)
0.556
3
UniProt:P56524 HDAC4
3
polySUMO2,3-K559-HDAC4 [nucleoplasm]
(R-HSA-4616029)
monoSUMO1-K559-HDAC4 [nucleoplasm]
(R-HSA-4616016)
HDAC4 [nucleoplasm]
(R-HSA-351581)
0.556
3
UniProt:P29597 TYK2
5
p-Y-TYK2 [cytosol]
(R-HSA-6784366)
p-TYK2 [cytosol]
(R-HSA-8950424)
TYK2 [cytosol]
(R-HSA-877348)
p-Y1054,Y1055-TYK2 [cytosol]
(R-HSA-909682)
p-Y1054-TYK2 [cytosol]
(R-HSA-1112598)
0.556
3
UniProt:Q8WUK0 PTPMT1
1
PTPMT1 [mitochondrial inner membrane]
(R-HSA-3446802)
0.556
3
UniProt:P49639 HOXA1
1
HOXA1 [nucleoplasm]
(R-HSA-5617464)
0.556
3
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