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About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Content
Table of Contents
DOIs
Data Schema
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
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KRT40 [cytosol]
Stable Identifier
R-HSA-6809605
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Keratin, type I cytoskeletal 40, K1C40_HUMAN
Locations in the PathwayBrowser
Expand all
Developmental Biology (Homo sapiens)
Keratinization (Homo sapiens)
Formation of hair keratin fibres (Homo sapiens)
Keratin tonofilament [cytosol] (Homo sapiens)
Keratin filament [cytosol] (Homo sapiens)
Keratin filament units [cytosol] (Homo sapiens)
Keratin tetramer [cytosol] (Homo sapiens)
Keratin heterodimer [cytosol] (Homo sapiens)
Keratin type I [cytosol] (Homo sapiens)
Keratin type I, hair specific [cytosol] (Homo sapiens)
KRT40 [cytosol] (Homo sapiens)
Keratin unit length filament [cytosol] (Homo sapiens)
Keratin tetramer [cytosol] (Homo sapiens)
Keratin heterodimer [cytosol] (Homo sapiens)
Keratin type I [cytosol] (Homo sapiens)
Keratin type I, hair specific [cytosol] (Homo sapiens)
KRT40 [cytosol] (Homo sapiens)
Keratin tonofilament:Keratin associated proteins polymer [cytosol] (Homo sapiens)
Keratin tonofilament, KAPs [cytosol] (Homo sapiens)
Keratin tonofilament [cytosol] (Homo sapiens)
Keratin filament [cytosol] (Homo sapiens)
Keratin filament units [cytosol] (Homo sapiens)
Keratin tetramer [cytosol] (Homo sapiens)
Keratin heterodimer [cytosol] (Homo sapiens)
Keratin type I [cytosol] (Homo sapiens)
Keratin type I, hair specific [cytosol] (Homo sapiens)
KRT40 [cytosol] (Homo sapiens)
Keratin unit length filament [cytosol] (Homo sapiens)
Keratin tetramer [cytosol] (Homo sapiens)
Keratin heterodimer [cytosol] (Homo sapiens)
Keratin type I [cytosol] (Homo sapiens)
Keratin type I, hair specific [cytosol] (Homo sapiens)
KRT40 [cytosol] (Homo sapiens)
Formation of the cornified envelope (Homo sapiens)
CASP14 cleaves filaggrin (Homo sapiens)
Late cornified envelope [plasma membrane] (Homo sapiens)
Cornified envelope:CDSN [plasma membrane] (Homo sapiens)
Cornified envelope [plasma membrane] (Homo sapiens)
Early cornified envelope [plasma membrane] (Homo sapiens)
FLG-Keratin filament network [plasma membrane] (Homo sapiens)
FLG(?-?):Keratin tonofilament:Desmosome [plasma membrane] (Homo sapiens)
Keratin tonofilament:Desmosome [plasma membrane] (Homo sapiens)
Keratin tonofilament [cytosol] (Homo sapiens)
Keratin filament [cytosol] (Homo sapiens)
Keratin filament units [cytosol] (Homo sapiens)
Keratin tetramer [cytosol] (Homo sapiens)
Keratin heterodimer [cytosol] (Homo sapiens)
Keratin type I [cytosol] (Homo sapiens)
Keratin type I, hair specific [cytosol] (Homo sapiens)
KRT40 [cytosol] (Homo sapiens)
Keratin unit length filament [cytosol] (Homo sapiens)
Keratin tetramer [cytosol] (Homo sapiens)
Keratin heterodimer [cytosol] (Homo sapiens)
Keratin type I [cytosol] (Homo sapiens)
Keratin type I, hair specific [cytosol] (Homo sapiens)
KRT40 [cytosol] (Homo sapiens)
Mature cornified envelope [plasma membrane] (Homo sapiens)
No FGN-cornified envelope:CDSN [plasma membrane] (Homo sapiens)
No FGN-Cornified envelope [plasma membrane] (Homo sapiens)
No FGN-late cornified envelope [plasma membrane] (Homo sapiens)
Keratin tonofilament:Desmosome network [plasma membrane] (Homo sapiens)
Keratin tonofilament:Desmosome [plasma membrane] (Homo sapiens)
Keratin tonofilament [cytosol] (Homo sapiens)
Keratin filament [cytosol] (Homo sapiens)
Keratin filament units [cytosol] (Homo sapiens)
Keratin tetramer [cytosol] (Homo sapiens)
Keratin heterodimer [cytosol] (Homo sapiens)
Keratin type I [cytosol] (Homo sapiens)
Keratin type I, hair specific [cytosol] (Homo sapiens)
KRT40 [cytosol] (Homo sapiens)
Keratin unit length filament [cytosol] (Homo sapiens)
Keratin tetramer [cytosol] (Homo sapiens)
Keratin heterodimer [cytosol] (Homo sapiens)
Keratin type I [cytosol] (Homo sapiens)
Keratin type I, hair specific [cytosol] (Homo sapiens)
KRT40 [cytosol] (Homo sapiens)
CDSN binds the cornified envelope (Homo sapiens)
Cornified envelope [plasma membrane] (Homo sapiens)
Early cornified envelope [plasma membrane] (Homo sapiens)
FLG-Keratin filament network [plasma membrane] (Homo sapiens)
FLG(?-?):Keratin tonofilament:Desmosome [plasma membrane] (Homo sapiens)
Keratin tonofilament:Desmosome [plasma membrane] (Homo sapiens)
Keratin tonofilament [cytosol] (Homo sapiens)
Keratin filament [cytosol] (Homo sapiens)
Keratin filament units [cytosol] (Homo sapiens)
Keratin tetramer [cytosol] (Homo sapiens)
Keratin heterodimer [cytosol] (Homo sapiens)
Keratin type I [cytosol] (Homo sapiens)
Keratin type I, hair specific [cytosol] (Homo sapiens)
KRT40 [cytosol] (Homo sapiens)
Keratin unit length filament [cytosol] (Homo sapiens)
Keratin tetramer [cytosol] (Homo sapiens)
Keratin heterodimer [cytosol] (Homo sapiens)
Keratin type I [cytosol] (Homo sapiens)
Keratin type I, hair specific [cytosol] (Homo sapiens)
KRT40 [cytosol] (Homo sapiens)
Cornified envelope:CDSN [plasma membrane] (Homo sapiens)
Cornified envelope [plasma membrane] (Homo sapiens)
Early cornified envelope [plasma membrane] (Homo sapiens)
FLG-Keratin filament network [plasma membrane] (Homo sapiens)
FLG(?-?):Keratin tonofilament:Desmosome [plasma membrane] (Homo sapiens)
Keratin tonofilament:Desmosome [plasma membrane] (Homo sapiens)
Keratin tonofilament [cytosol] (Homo sapiens)
Keratin filament [cytosol] (Homo sapiens)
Keratin filament units [cytosol] (Homo sapiens)
Keratin tetramer [cytosol] (Homo sapiens)
Keratin heterodimer [cytosol] (Homo sapiens)
Keratin type I [cytosol] (Homo sapiens)
Keratin type I, hair specific [cytosol] (Homo sapiens)
KRT40 [cytosol] (Homo sapiens)
Keratin unit length filament [cytosol] (Homo sapiens)
Keratin tetramer [cytosol] (Homo sapiens)
Keratin heterodimer [cytosol] (Homo sapiens)
Keratin type I [cytosol] (Homo sapiens)
Keratin type I, hair specific [cytosol] (Homo sapiens)
KRT40 [cytosol] (Homo sapiens)
Filaggrin binds Keratin tonofilament:Desmosome (Homo sapiens)
FLG(?-?):Keratin tonofilament:Desmosome [plasma membrane] (Homo sapiens)
Keratin tonofilament:Desmosome [plasma membrane] (Homo sapiens)
Keratin tonofilament [cytosol] (Homo sapiens)
Keratin filament [cytosol] (Homo sapiens)
Keratin filament units [cytosol] (Homo sapiens)
Keratin tetramer [cytosol] (Homo sapiens)
Keratin heterodimer [cytosol] (Homo sapiens)
Keratin type I [cytosol] (Homo sapiens)
Keratin type I, hair specific [cytosol] (Homo sapiens)
KRT40 [cytosol] (Homo sapiens)
Keratin unit length filament [cytosol] (Homo sapiens)
Keratin tetramer [cytosol] (Homo sapiens)
Keratin heterodimer [cytosol] (Homo sapiens)
Keratin type I [cytosol] (Homo sapiens)
Keratin type I, hair specific [cytosol] (Homo sapiens)
KRT40 [cytosol] (Homo sapiens)
Keratin tonofilament:Desmosome [plasma membrane] (Homo sapiens)
Keratin tonofilament [cytosol] (Homo sapiens)
Keratin filament [cytosol] (Homo sapiens)
Keratin filament units [cytosol] (Homo sapiens)
Keratin tetramer [cytosol] (Homo sapiens)
Keratin heterodimer [cytosol] (Homo sapiens)
Keratin type I [cytosol] (Homo sapiens)
Keratin type I, hair specific [cytosol] (Homo sapiens)
KRT40 [cytosol] (Homo sapiens)
Keratin unit length filament [cytosol] (Homo sapiens)
Keratin tetramer [cytosol] (Homo sapiens)
Keratin heterodimer [cytosol] (Homo sapiens)
Keratin type I [cytosol] (Homo sapiens)
Keratin type I, hair specific [cytosol] (Homo sapiens)
KRT40 [cytosol] (Homo sapiens)
Fillagrin and keratin intermediate filaments polymerise forming a network (Homo sapiens)
FLG(?-?):Keratin tonofilament:Desmosome [plasma membrane] (Homo sapiens)
Keratin tonofilament:Desmosome [plasma membrane] (Homo sapiens)
Keratin tonofilament [cytosol] (Homo sapiens)
Keratin filament [cytosol] (Homo sapiens)
Keratin filament units [cytosol] (Homo sapiens)
Keratin tetramer [cytosol] (Homo sapiens)
Keratin heterodimer [cytosol] (Homo sapiens)
Keratin type I [cytosol] (Homo sapiens)
Keratin type I, hair specific [cytosol] (Homo sapiens)
KRT40 [cytosol] (Homo sapiens)
Keratin unit length filament [cytosol] (Homo sapiens)
Keratin tetramer [cytosol] (Homo sapiens)
Keratin heterodimer [cytosol] (Homo sapiens)
Keratin type I [cytosol] (Homo sapiens)
Keratin type I, hair specific [cytosol] (Homo sapiens)
KRT40 [cytosol] (Homo sapiens)
FLG-Keratin filament network [plasma membrane] (Homo sapiens)
FLG(?-?):Keratin tonofilament:Desmosome [plasma membrane] (Homo sapiens)
Keratin tonofilament:Desmosome [plasma membrane] (Homo sapiens)
Keratin tonofilament [cytosol] (Homo sapiens)
Keratin filament [cytosol] (Homo sapiens)
Keratin filament units [cytosol] (Homo sapiens)
Keratin tetramer [cytosol] (Homo sapiens)
Keratin heterodimer [cytosol] (Homo sapiens)
Keratin type I [cytosol] (Homo sapiens)
Keratin type I, hair specific [cytosol] (Homo sapiens)
KRT40 [cytosol] (Homo sapiens)
Keratin unit length filament [cytosol] (Homo sapiens)
Keratin tetramer [cytosol] (Homo sapiens)
Keratin heterodimer [cytosol] (Homo sapiens)
Keratin type I [cytosol] (Homo sapiens)
Keratin type I, hair specific [cytosol] (Homo sapiens)
KRT40 [cytosol] (Homo sapiens)
Lamellar bodies bind the early cornified envelope (Homo sapiens)
Cornified envelope [plasma membrane] (Homo sapiens)
Early cornified envelope [plasma membrane] (Homo sapiens)
FLG-Keratin filament network [plasma membrane] (Homo sapiens)
FLG(?-?):Keratin tonofilament:Desmosome [plasma membrane] (Homo sapiens)
Keratin tonofilament:Desmosome [plasma membrane] (Homo sapiens)
Keratin tonofilament [cytosol] (Homo sapiens)
Keratin filament [cytosol] (Homo sapiens)
Keratin filament units [cytosol] (Homo sapiens)
Keratin tetramer [cytosol] (Homo sapiens)
Keratin heterodimer [cytosol] (Homo sapiens)
Keratin type I [cytosol] (Homo sapiens)
Keratin type I, hair specific [cytosol] (Homo sapiens)
KRT40 [cytosol] (Homo sapiens)
Keratin unit length filament [cytosol] (Homo sapiens)
Keratin tetramer [cytosol] (Homo sapiens)
Keratin heterodimer [cytosol] (Homo sapiens)
Keratin type I [cytosol] (Homo sapiens)
Keratin type I, hair specific [cytosol] (Homo sapiens)
KRT40 [cytosol] (Homo sapiens)
Early cornified envelope [plasma membrane] (Homo sapiens)
FLG-Keratin filament network [plasma membrane] (Homo sapiens)
FLG(?-?):Keratin tonofilament:Desmosome [plasma membrane] (Homo sapiens)
Keratin tonofilament:Desmosome [plasma membrane] (Homo sapiens)
Keratin tonofilament [cytosol] (Homo sapiens)
Keratin filament [cytosol] (Homo sapiens)
Keratin filament units [cytosol] (Homo sapiens)
Keratin tetramer [cytosol] (Homo sapiens)
Keratin heterodimer [cytosol] (Homo sapiens)
Keratin type I [cytosol] (Homo sapiens)
Keratin type I, hair specific [cytosol] (Homo sapiens)
KRT40 [cytosol] (Homo sapiens)
Keratin unit length filament [cytosol] (Homo sapiens)
Keratin tetramer [cytosol] (Homo sapiens)
Keratin heterodimer [cytosol] (Homo sapiens)
Keratin type I [cytosol] (Homo sapiens)
Keratin type I, hair specific [cytosol] (Homo sapiens)
KRT40 [cytosol] (Homo sapiens)
Late envelope proteins bind cornified envelope:CDSN (Homo sapiens)
Cornified envelope:CDSN [plasma membrane] (Homo sapiens)
Cornified envelope [plasma membrane] (Homo sapiens)
Early cornified envelope [plasma membrane] (Homo sapiens)
FLG-Keratin filament network [plasma membrane] (Homo sapiens)
FLG(?-?):Keratin tonofilament:Desmosome [plasma membrane] (Homo sapiens)
Keratin tonofilament:Desmosome [plasma membrane] (Homo sapiens)
Keratin tonofilament [cytosol] (Homo sapiens)
Keratin filament [cytosol] (Homo sapiens)
Keratin filament units [cytosol] (Homo sapiens)
Keratin tetramer [cytosol] (Homo sapiens)
Keratin heterodimer [cytosol] (Homo sapiens)
Keratin type I [cytosol] (Homo sapiens)
Keratin type I, hair specific [cytosol] (Homo sapiens)
KRT40 [cytosol] (Homo sapiens)
Keratin unit length filament [cytosol] (Homo sapiens)
Keratin tetramer [cytosol] (Homo sapiens)
Keratin heterodimer [cytosol] (Homo sapiens)
Keratin type I [cytosol] (Homo sapiens)
Keratin type I, hair specific [cytosol] (Homo sapiens)
KRT40 [cytosol] (Homo sapiens)
Late cornified envelope [plasma membrane] (Homo sapiens)
Cornified envelope:CDSN [plasma membrane] (Homo sapiens)
Cornified envelope [plasma membrane] (Homo sapiens)
Early cornified envelope [plasma membrane] (Homo sapiens)
FLG-Keratin filament network [plasma membrane] (Homo sapiens)
FLG(?-?):Keratin tonofilament:Desmosome [plasma membrane] (Homo sapiens)
Keratin tonofilament:Desmosome [plasma membrane] (Homo sapiens)
Keratin tonofilament [cytosol] (Homo sapiens)
Keratin filament [cytosol] (Homo sapiens)
Keratin filament units [cytosol] (Homo sapiens)
Keratin tetramer [cytosol] (Homo sapiens)
Keratin heterodimer [cytosol] (Homo sapiens)
Keratin type I [cytosol] (Homo sapiens)
Keratin type I, hair specific [cytosol] (Homo sapiens)
KRT40 [cytosol] (Homo sapiens)
Keratin unit length filament [cytosol] (Homo sapiens)
Keratin tetramer [cytosol] (Homo sapiens)
Keratin heterodimer [cytosol] (Homo sapiens)
Keratin type I [cytosol] (Homo sapiens)
Keratin type I, hair specific [cytosol] (Homo sapiens)
KRT40 [cytosol] (Homo sapiens)
Plasma membrane resorption (Homo sapiens)
Mature cornified envelope [cornified envelope] (Homo sapiens)
No FGN-cornified envelope:CDSN [cornified envelope] (Homo sapiens)
No FGN-Cornified envelope [cornified envelope] (Homo sapiens)
No FGN-early cornified envelope [cornified envelope] (Homo sapiens)
Keratin tonofilament:Desmosome network [cornified envelope] (Homo sapiens)
Keratin tonofilament:Desmosome [cornified envelope] (Homo sapiens)
Keratin tonofilament [cytosol] (Homo sapiens)
Keratin filament [cytosol] (Homo sapiens)
Keratin filament units [cytosol] (Homo sapiens)
Keratin tetramer [cytosol] (Homo sapiens)
Keratin heterodimer [cytosol] (Homo sapiens)
Keratin type I [cytosol] (Homo sapiens)
Keratin type I, hair specific [cytosol] (Homo sapiens)
KRT40 [cytosol] (Homo sapiens)
Keratin unit length filament [cytosol] (Homo sapiens)
Keratin tetramer [cytosol] (Homo sapiens)
Keratin heterodimer [cytosol] (Homo sapiens)
Keratin type I [cytosol] (Homo sapiens)
Keratin type I, hair specific [cytosol] (Homo sapiens)
KRT40 [cytosol] (Homo sapiens)
Mature cornified envelope [plasma membrane] (Homo sapiens)
No FGN-cornified envelope:CDSN [plasma membrane] (Homo sapiens)
No FGN-Cornified envelope [plasma membrane] (Homo sapiens)
No FGN-late cornified envelope [plasma membrane] (Homo sapiens)
Keratin tonofilament:Desmosome network [plasma membrane] (Homo sapiens)
Keratin tonofilament:Desmosome [plasma membrane] (Homo sapiens)
Keratin tonofilament [cytosol] (Homo sapiens)
Keratin filament [cytosol] (Homo sapiens)
Keratin filament units [cytosol] (Homo sapiens)
Keratin tetramer [cytosol] (Homo sapiens)
Keratin heterodimer [cytosol] (Homo sapiens)
Keratin type I [cytosol] (Homo sapiens)
Keratin type I, hair specific [cytosol] (Homo sapiens)
KRT40 [cytosol] (Homo sapiens)
Keratin unit length filament [cytosol] (Homo sapiens)
Keratin tetramer [cytosol] (Homo sapiens)
Keratin heterodimer [cytosol] (Homo sapiens)
Keratin type I [cytosol] (Homo sapiens)
Keratin type I, hair specific [cytosol] (Homo sapiens)
KRT40 [cytosol] (Homo sapiens)
Reinforcement of the Cornified Envelope (Homo sapiens)
Early cornified envelope [plasma membrane] (Homo sapiens)
FLG-Keratin filament network [plasma membrane] (Homo sapiens)
FLG(?-?):Keratin tonofilament:Desmosome [plasma membrane] (Homo sapiens)
Keratin tonofilament:Desmosome [plasma membrane] (Homo sapiens)
Keratin tonofilament [cytosol] (Homo sapiens)
Keratin filament [cytosol] (Homo sapiens)
Keratin filament units [cytosol] (Homo sapiens)
Keratin tetramer [cytosol] (Homo sapiens)
Keratin heterodimer [cytosol] (Homo sapiens)
Keratin type I [cytosol] (Homo sapiens)
Keratin type I, hair specific [cytosol] (Homo sapiens)
KRT40 [cytosol] (Homo sapiens)
Keratin unit length filament [cytosol] (Homo sapiens)
Keratin tetramer [cytosol] (Homo sapiens)
Keratin heterodimer [cytosol] (Homo sapiens)
Keratin type I [cytosol] (Homo sapiens)
Keratin type I, hair specific [cytosol] (Homo sapiens)
KRT40 [cytosol] (Homo sapiens)
FLG-Keratin filament network [plasma membrane] (Homo sapiens)
FLG(?-?):Keratin tonofilament:Desmosome [plasma membrane] (Homo sapiens)
Keratin tonofilament:Desmosome [plasma membrane] (Homo sapiens)
Keratin tonofilament [cytosol] (Homo sapiens)
Keratin filament [cytosol] (Homo sapiens)
Keratin filament units [cytosol] (Homo sapiens)
Keratin tetramer [cytosol] (Homo sapiens)
Keratin heterodimer [cytosol] (Homo sapiens)
Keratin type I [cytosol] (Homo sapiens)
Keratin type I, hair specific [cytosol] (Homo sapiens)
KRT40 [cytosol] (Homo sapiens)
Keratin unit length filament [cytosol] (Homo sapiens)
Keratin tetramer [cytosol] (Homo sapiens)
Keratin heterodimer [cytosol] (Homo sapiens)
Keratin type I [cytosol] (Homo sapiens)
Keratin type I, hair specific [cytosol] (Homo sapiens)
KRT40 [cytosol] (Homo sapiens)
Formation of tonofilament bundles (Homo sapiens)
Keratin filament [cytosol] (Homo sapiens)
Keratin filament units [cytosol] (Homo sapiens)
Keratin tetramer [cytosol] (Homo sapiens)
Keratin heterodimer [cytosol] (Homo sapiens)
Keratin type I [cytosol] (Homo sapiens)
Keratin type I, hair specific [cytosol] (Homo sapiens)
KRT40 [cytosol] (Homo sapiens)
Keratin unit length filament [cytosol] (Homo sapiens)
Keratin tetramer [cytosol] (Homo sapiens)
Keratin heterodimer [cytosol] (Homo sapiens)
Keratin type I [cytosol] (Homo sapiens)
Keratin type I, hair specific [cytosol] (Homo sapiens)
KRT40 [cytosol] (Homo sapiens)
Keratin tonofilament [cytosol] (Homo sapiens)
Keratin filament [cytosol] (Homo sapiens)
Keratin filament units [cytosol] (Homo sapiens)
Keratin tetramer [cytosol] (Homo sapiens)
Keratin heterodimer [cytosol] (Homo sapiens)
Keratin type I [cytosol] (Homo sapiens)
Keratin type I, hair specific [cytosol] (Homo sapiens)
KRT40 [cytosol] (Homo sapiens)
Keratin unit length filament [cytosol] (Homo sapiens)
Keratin tetramer [cytosol] (Homo sapiens)
Keratin heterodimer [cytosol] (Homo sapiens)
Keratin type I [cytosol] (Homo sapiens)
Keratin type I, hair specific [cytosol] (Homo sapiens)
KRT40 [cytosol] (Homo sapiens)
Keratin filament formation (Homo sapiens)
Keratin filament [cytosol] (Homo sapiens)
Keratin filament units [cytosol] (Homo sapiens)
Keratin tetramer [cytosol] (Homo sapiens)
Keratin heterodimer [cytosol] (Homo sapiens)
Keratin type I [cytosol] (Homo sapiens)
Keratin type I, hair specific [cytosol] (Homo sapiens)
KRT40 [cytosol] (Homo sapiens)
Keratin unit length filament [cytosol] (Homo sapiens)
Keratin tetramer [cytosol] (Homo sapiens)
Keratin heterodimer [cytosol] (Homo sapiens)
Keratin type I [cytosol] (Homo sapiens)
Keratin type I, hair specific [cytosol] (Homo sapiens)
KRT40 [cytosol] (Homo sapiens)
Keratin filament units [cytosol] (Homo sapiens)
Keratin tetramer [cytosol] (Homo sapiens)
Keratin heterodimer [cytosol] (Homo sapiens)
Keratin type I [cytosol] (Homo sapiens)
Keratin type I, hair specific [cytosol] (Homo sapiens)
KRT40 [cytosol] (Homo sapiens)
Keratin unit length filament [cytosol] (Homo sapiens)
Keratin tetramer [cytosol] (Homo sapiens)
Keratin heterodimer [cytosol] (Homo sapiens)
Keratin type I [cytosol] (Homo sapiens)
Keratin type I, hair specific [cytosol] (Homo sapiens)
KRT40 [cytosol] (Homo sapiens)
Keratin filaments bind cell-cell adhesion complexes (Homo sapiens)
Keratin tonofilament [cytosol] (Homo sapiens)
Keratin filament [cytosol] (Homo sapiens)
Keratin filament units [cytosol] (Homo sapiens)
Keratin tetramer [cytosol] (Homo sapiens)
Keratin heterodimer [cytosol] (Homo sapiens)
Keratin type I [cytosol] (Homo sapiens)
Keratin type I, hair specific [cytosol] (Homo sapiens)
KRT40 [cytosol] (Homo sapiens)
Keratin unit length filament [cytosol] (Homo sapiens)
Keratin tetramer [cytosol] (Homo sapiens)
Keratin heterodimer [cytosol] (Homo sapiens)
Keratin type I [cytosol] (Homo sapiens)
Keratin type I, hair specific [cytosol] (Homo sapiens)
KRT40 [cytosol] (Homo sapiens)
Keratin tonofilament:Desmosome [plasma membrane] (Homo sapiens)
Keratin tonofilament [cytosol] (Homo sapiens)
Keratin filament [cytosol] (Homo sapiens)
Keratin filament units [cytosol] (Homo sapiens)
Keratin tetramer [cytosol] (Homo sapiens)
Keratin heterodimer [cytosol] (Homo sapiens)
Keratin type I [cytosol] (Homo sapiens)
Keratin type I, hair specific [cytosol] (Homo sapiens)
KRT40 [cytosol] (Homo sapiens)
Keratin unit length filament [cytosol] (Homo sapiens)
Keratin tetramer [cytosol] (Homo sapiens)
Keratin heterodimer [cytosol] (Homo sapiens)
Keratin type I [cytosol] (Homo sapiens)
Keratin type I, hair specific [cytosol] (Homo sapiens)
KRT40 [cytosol] (Homo sapiens)
Keratin tetramers bind to form unit length filaments (Homo sapiens)
Keratin tetramer [cytosol] (Homo sapiens)
Keratin heterodimer [cytosol] (Homo sapiens)
Keratin type I [cytosol] (Homo sapiens)
Keratin type I, hair specific [cytosol] (Homo sapiens)
KRT40 [cytosol] (Homo sapiens)
Keratin unit length filament [cytosol] (Homo sapiens)
Keratin tetramer [cytosol] (Homo sapiens)
Keratin heterodimer [cytosol] (Homo sapiens)
Keratin type I [cytosol] (Homo sapiens)
Keratin type I, hair specific [cytosol] (Homo sapiens)
KRT40 [cytosol] (Homo sapiens)
Keratin type I binds keratin type II (Homo sapiens)
Keratin heterodimer [cytosol] (Homo sapiens)
Keratin type I [cytosol] (Homo sapiens)
Keratin type I, hair specific [cytosol] (Homo sapiens)
KRT40 [cytosol] (Homo sapiens)
Keratin type I [cytosol] (Homo sapiens)
Keratin type I, hair specific [cytosol] (Homo sapiens)
KRT40 [cytosol] (Homo sapiens)
Keratin type I/type II heterodimers form tetramers (Homo sapiens)
Keratin heterodimer [cytosol] (Homo sapiens)
Keratin type I [cytosol] (Homo sapiens)
Keratin type I, hair specific [cytosol] (Homo sapiens)
KRT40 [cytosol] (Homo sapiens)
Keratin tetramer [cytosol] (Homo sapiens)
Keratin heterodimer [cytosol] (Homo sapiens)
Keratin type I [cytosol] (Homo sapiens)
Keratin type I, hair specific [cytosol] (Homo sapiens)
KRT40 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q6A162 KRT40
Gene Names
KRT40, KA36
Chain
chain:1-431
Reference Genes
BioGPS Gene:125115 KRT40
COSMIC (genes):KRT40 KRT40
CTD Gene:125115 KRT40
dbSNP Gene:125115 KRT40
ENSEMBL:ENSG00000204889 KRT40
ENSEMBL:ENSG00000262845 KRT40
HGNC:26707 KRT40
KEGG Gene (Homo sapiens):125115 KRT40
Monarch:125115 KRT40
NCBI Gene:125115 KRT40
OMIM:616679 KRT40
UCSC:Q6A162 KRT40
Reference Transcript
RefSeq:NM_182497.3 KRT40
Other Identifiers
0005360017
11738403_at
11738404_s_at
125115
1562628_at
1562629_a_at
16844533
3756631
3756633
3756634
3756636
3756637
3756641
3756643
3756644
3756645
3756646
3756647
8015152
8019604
A_33_P3310894
GE477047
GO:0003674
GO:0005198
GO:0005515
GO:0005575
GO:0005622
GO:0005737
GO:0005829
GO:0005856
GO:0005882
GO:0008150
GO:0008219
GO:0030154
GO:0031424
GO:0043226
GO:0048856
GO:0070268
HMNXSV003005746
Hs2.146635.1.S1_3p_at
ILMN_1658563
ILMN_1663578
PH_hs_0031822
PH_hs_0040615
TC17001475.hg
Participates
as a member of
Keratin type I, hair specific [cytosol] (Homo sapiens)
Inferred To
Homologues of KRT40 [cytosol]
(Danio rerio)
Homologues of KRT40 [cytosol]
(Xenopus tropicalis)
krt93 [cytosol]
(Danio rerio)
krt92 [cytosol]
(Danio rerio)
krt91 [cytosol]
(Danio rerio)
cyt1l [cytosol]
(Danio rerio)
krt94 [cytosol]
(Danio rerio)
cyt1 [cytosol]
(Danio rerio)
krt95 [cytosol]
(Danio rerio)
krt17 [cytosol]
(Danio rerio)
Krt40 [cytosol]
(Mus musculus)
Krt40 [cytosol]
(Rattus norvegicus)
krt96 [cytosol]
(Danio rerio)
krt97 [cytosol]
(Danio rerio)
si:ch211-156l18.7 [cytosol]
(Danio rerio)
krt15 [cytosol]
(Danio rerio)
KRT40 [cytosol]
(Bos taurus)
KRT40 [cytosol]
(Canis familiaris)
KRT40 [cytosol]
(Danio rerio)
KRT40 [cytosol]
(Sus scrofa)
KRT40 [cytosol]
(Xenopus tropicalis)
krtt1c19e [cytosol]
(Danio rerio)
krt99 [cytosol]
(Danio rerio)
krt1-19d [cytosol]
(Danio rerio)
krt98 [cytosol]
(Danio rerio)
ouro2 [cytosol]
(Xenopus tropicalis)
Cross References
RefSeq
NP_872303.2
OpenTargets
ENSG00000204889
GeneCards
Q6A162
HPA
ENSG00000204889-KRT40
Ensembl
ENSP00000479080
,
ENSP00000381500
,
ENSP00000459621
,
ENSP00000366984
,
ENSG00000204889
,
ENST00000610983
,
ENST00000576967
,
ENSG00000262845
,
ENST00000398486
,
ENST00000377755
PRO
Q6A162
Pharos - Targets
Q6A162
Interactors (50)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P40222 TXLNA
1
TXLNA [cytosol]
(R-HSA-449124)
0.718
6
UniProt:O75604 USP2
2
USP2 [nucleoplasm]
(R-HSA-5689946)
USP2 [cytosol]
(R-HSA-5212661)
0.718
6
UniProt:Q13895 BYSL
2
BYSL [nucleoplasm]
(R-HSA-6791526)
BYSL [cytosol]
(R-HSA-6791518)
0.718
8
UniProt:Q92608 DOCK2
3
DOCK2 [extracellular region]
(R-HSA-6806310)
DOCK2 [specific granule lumen]
(R-HSA-6799558)
DOCK2 [cytosol]
(R-HSA-200938)
0.718
6
UniProt:O14964 HGS
2
HGS [cytosol]
(R-HSA-182954)
HGS [phagocytic vesicle lumen]
(R-HSA-9635660)
0.718
6
UniProt:P99999 CYCS
4
CYCS [mitochondrial intermembrane space]
(R-HSA-114244)
CYCS [mitochondrial inner membrane]
(R-HSA-352608)
AcK-CYCS [mitochondrial intermembrane space]
(R-HSA-5688308)
CYCS [cytosol]
(R-HSA-53259)
0.718
6
UniProt:Q15561 TEAD4
1
TEAD4 [nucleoplasm]
(R-HSA-2032780)
0.718
6
UniProt:O95363 FARS2
1
FARS2(1-?) [mitochondrial matrix]
(R-HSA-379565)
0.718
6
UniProt:Q13330 MTA1
2
SUMO2,3-K509-MTA1 [nucleoplasm]
(R-HSA-3465537)
MTA1 [nucleoplasm]
(R-HSA-3465550)
0.666
4
UniProt:P19544 WT1
1
WT1 [nucleoplasm]
(R-HSA-452420)
0.666
4
UniProt:Q13526 PIN1
2
PIN1 [nucleoplasm]
(R-HSA-936016)
PIN1 [cytosol]
(R-HSA-9626823)
0.556
3
UniProt:P52292 KPNA2
2
KPNA2 [nucleoplasm]
(R-HSA-206045)
KPNA2 [cytosol]
(R-HSA-205976)
0.556
3
UniProt:Q96E11 MRRF
1
MRRF [mitochondrial matrix]
(R-HSA-5419265)
0.556
3
UniProt:Q08117 TLE5
1
AES [nucleoplasm]
(R-HSA-4648963)
0.556
3
UniProt:O60341 KDM1A
1
KDM1A [nucleoplasm]
(R-HSA-996769)
0.556
3
UniProt:P29597 TYK2
5
p-Y1054,Y1055-TYK2 [cytosol]
(R-HSA-909682)
p-TYK2 [cytosol]
(R-HSA-8950424)
TYK2 [cytosol]
(R-HSA-877348)
p-Y1054-TYK2 [cytosol]
(R-HSA-1112598)
p-Y-TYK2 [cytosol]
(R-HSA-6784366)
0.556
3
UniProt:Q99757 TXN2
3
2xHC-TXN2 [mitochondrial matrix]
(R-HSA-3323059)
TXN2 [mitochondrial matrix]
(R-HSA-3323048)
HC-TXN2 [mitochondrial matrix]
(R-HSA-9035482)
0.556
3
UniProt:Q4G176 ACSF3
1
ACSF3 [mitochondrial matrix]
(R-HSA-5696011)
0.556
3
UniProt:Q9UBK9 UXT
1
UXT [nucleoplasm]
(R-HSA-9007484)
0.556
3
UniProt:P08631 HCK
2
HCK [cytosol]
(R-HSA-167708)
p-HCK [cytosol]
(R-HSA-9676060)
0.556
3
UniProt:P63000 RAC1
6
RAC1 [secretory granule membrane]
(R-HSA-6804770)
RAC1 [cytosol]
(R-HSA-442615)
GGC-PalmC-RAC1 [plasma membrane]
(R-HSA-2316446)
RAC1 [ficolin-1-rich granule membrane]
(R-HSA-6804802)
RAC1 [endoplasmic reticulum membrane]
(R-HSA-5672076)
RAC1 [plasma membrane]
(R-HSA-351141)
0.556
3
UniProt:Q9UBX3 SLC25A10
1
SLC25A10 [mitochondrial inner membrane]
(R-HSA-372848)
0.556
3
UniProt:Q9UBU9 NXF1
2
NXF1 [cytosol]
(R-HSA-156481)
NXF1 [nucleoplasm]
(R-HSA-111690)
0.556
3
UniProt:Q49AN0 CRY2
4
p-S-CRY2 [cytosol]
(R-HSA-400305)
CRY2 [cytosol]
(R-HSA-400255)
p-S-CRY2 [nucleoplasm]
(R-HSA-400328)
Ub-p-S-CRY2 [nucleoplasm]
(R-HSA-517935)
0.556
3
UniProt:Q9UBR2 CTSZ
9
CTSZ [ficolin-1-rich granule lumen]
(R-HSA-6801318)
CTSZ [Golgi lumen]
(R-HSA-434321)
(Glc)3(GlcNAc)2(Man)9-CTSZ [COPII-coated ER to Golgi transport vesicle]
(R-HSA-5689727)
CTSZ [specific granule lumen]
(R-HSA-6801304)
(Glc)3(GlcNAc)2(Man)9-CTSZ [endoplasmic reticulum lumen]
(R-HSA-5689431)
(Glc)3(GlcNAc)2(Man)9-CTSZ [endoplasmic reticulum-Golgi intermediate compartment membrane]
(R-HSA-5689730)
CTSZ [plasma membrane]
(R-HSA-2022345)
CTSZ [extracellular region]
(R-HSA-6801569)
CTSZ [lysosomal lumen]
(R-HSA-429814)
0.556
3
UniProt:Q9UIL1 SCOC
1
SCOC [cytosol]
(R-HSA-6813911)
0.556
3
UniProt:Q99728 BARD1
13
BARD1 C53W [nucleoplasm]
(R-HSA-9700807)
BARD1 C83G [nucleoplasm]
(R-HSA-9699139)
BARD1 C71Y [nucleoplasm]
(R-HSA-9700808)
BARD1 [nucleoplasm]
(R-HSA-5659775)
BARD1 C50G [nucleoplasm]
(R-HSA-9699137)
BARD1 W34R [nucleoplasm]
(R-HSA-9699166)
BARD1 G623W [nucleoplasm]
(R-HSA-9699148)
K6PolyUb-BARD1 [nucleoplasm]
(R-HSA-9701024)
BARD1 H68Y [nucleoplasm]
(R-HSA-9699151)
p-T714,T734-BARD1 [nucleoplasm]
(R-HSA-5659846)
BARD1 L44R [nucleoplasm]
(R-HSA-9699126)
BARD1 G623E [nucleoplasm]
(R-HSA-9699135)
K6PolyUb,p-T714,T734-BARD1 [nucleoplasm]
(R-HSA-9707286)
0.556
3
UniProt:O43602 DCX
1
DCX [cytosol]
(R-HSA-430060)
0.556
3
UniProt:O15169 AXIN1
11
AXIN1 W247* [cytosol]
(R-HSA-5251512)
AXIN1 P354L [cytosol]
(R-HSA-5251511)
AXIN1 Y346* [cytosol]
(R-HSA-4839753)
ub-AXIN1 [cytosol]
(R-HSA-4641133)
Ub-RibC-AXIN1 [cytosol]
(R-HSA-3640864)
AXIN1 E406* [cytosol]
(R-HSA-5251500)
AXIN1 P255S [cytosol]
(R-HSA-5251505)
AXIN1 [cytosol]
(R-HSA-195249)
p-T519,S524,S531-AXIN1 [cytosol]
(R-HSA-206040)
RibC-AXIN1 [cytosol]
(R-HSA-3640841)
AXIN1 L396M [cytosol]
(R-HSA-5251503)
0.556
3
UniProt:Q9H2F3 HSD3B7
1
HSD3B7 [endoplasmic reticulum membrane]
(R-HSA-193441)
0.556
3
UniProt:Q13573 SNW1
1
SNW1 [nucleoplasm]
(R-HSA-351663)
0.556
3
UniProt:P43353 ALDH3B1
3
ALDH3B1 [secretory granule membrane]
(R-HSA-6801023)
ALDH3B1 [plasma membrane]
(R-HSA-5696096)
ALDH3B1 [specific granule membrane]
(R-HSA-6799510)
0.556
3
UniProt:P26441 CNTF
1
CNTF [extracellular region]
(R-HSA-5696441)
0.556
3
UniProt:Q96HC4 PDLIM5
1
PDLIM5 [cytosol]
(R-HSA-6794246)
0.556
3
UniProt:Q9NX63 CHCHD3
3
CHCHD3 (MIC19) [mitochondrial inner membrane]
(R-HSA-8949583)
CHCHD3 [mitochondrial intermembrane space]
(R-HSA-8874907)
4xHC-CHCHD3 [mitochondrial intermembrane space]
(R-HSA-8874910)
0.556
3
UniProt:O95391 SLU7
1
hSLU7 [nucleoplasm]
(R-HSA-72073)
0.556
3
UniProt:P51959 CCNG1
1
CCNG1 [nucleoplasm]
(R-HSA-6792489)
0.556
3
UniProt:O60573 EIF4E2
1
EIF4E2 [cytosol]
(R-HSA-1678822)
0.556
3
UniProt:Q9H257 CARD9
3
CARD9 [cytosol]
(R-HSA-561194)
CARD9 [plasma membrane]
(R-HSA-5607662)
p-T231-CARD9 [plasma membrane]
(R-HSA-5607623)
0.556
3
UniProt:P49639 HOXA1
1
HOXA1 [nucleoplasm]
(R-HSA-5617464)
0.556
3
UniProt:P56524 HDAC4
3
SUMO2,3-K559-HDAC4 [nucleoplasm]
(R-HSA-4616029)
SUMO1-K559-HDAC4 [nucleoplasm]
(R-HSA-4616016)
HDAC4 [nucleoplasm]
(R-HSA-351581)
0.556
3
UniProt:Q9BZF9 UACA
1
UACA [cytosol]
(R-HSA-6804636)
0.556
3
UniProt:Q13875 MOBP
1
MOBP [cytosol]
(R-HSA-9022884)
0.556
3
UniProt:Q96QF0 RAB3IP
1
RAB3IP [cytosol]
(R-HSA-5617610)
0.556
3
UniProt:Q92993 KAT5
1
KAT5 [nucleoplasm]
(R-HSA-3321979)
0.556
3
UniProt:Q8WUK0 PTPMT1
1
PTPMT1 [mitochondrial inner membrane]
(R-HSA-3446802)
0.556
3
UniProt:Q92835 INPP5D
1
INPP5D [cytosol]
(R-HSA-197940)
0.556
3
UniProt:P23769 GATA2
1
GATA2 [nucleoplasm]
(R-HSA-996735)
0.556
3
UniProt:P10809 HSPD1
6
HSPD1(1-573) [mitochondrial inner membrane]
(R-HSA-1299442)
HSPD1(1-573) [mitochondrial intermembrane space]
(R-HSA-1267963)
HSPD1 [mitochondrial matrix]
(R-HSA-1299448)
HSPD1 [mitochondrial inner membrane]
(R-HSA-1299455)
HSPD1(1-26) [mitochondrial matrix]
(R-HSA-8986171)
HSPD1(1-573) [cytosol]
(R-HSA-1267989)
0.556
3
UniProt:P48023 FASLG
1
FASLG(1-281) [extracellular region]
(R-HSA-66212)
0.556
3
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