cis-Golgi t-SNAREs bind YKT6 on tethered vesicle

Stable Identifier
R-HSA-6809011
Type
Reaction [binding]
Species
Homo sapiens
Compartment
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Membrane fusion is mediated by the zippering of a four membered anti-parallel helix bundle formed by the v-SNARE and the three t-SNARES. t-SNARE complexes that are found at the cis-Golgi include STX5:GOSR1:GOSR2, STX5:GOSR1:BET1 and STX5:GOSR1:BET1L among others (Xu et al, 2002; Zhang et al 1997; Volchuk et al, 2004; reviewed in Willet et al, 2014; Szul and Sztul, 2011)

Literature References
PubMed ID Title Journal Year
9382863 The mammalian protein (rbet1) homologous to yeast Bet1p is primarily associated with the pre-Golgi intermediate compartment and is involved in vesicular transport from the endoplasmic reticulum to the Golgi apparatus

Zhang, T, Wong, SH, Tang, BL, Xu, Y, Peter, F, Subramaniam, VN, Hong, W

J. Cell Biol. 1997
22013193 COPII and COPI traffic at the ER-Golgi interface

Szul, T, Sztul, E

Physiology (Bethesda) 2011
14742712 Countercurrent distribution of two distinct SNARE complexes mediating transport within the Golgi stack

Volchuk, A, Ravazzola, M, Perrelet, A, Eng, WS, Di Liberto, M, Varlamov, O, Fukasawa, M, Engel, T, Söllner, TH, Rothman, JE, Orci, L

Mol. Biol. Cell 2004
23839779 The Golgi puppet master: COG complex at center stage of membrane trafficking interactions

Willett, R, Ungar, D, Lupashin, V

Histochem. Cell Biol. 2013
12388752 GS15 forms a SNARE complex with syntaxin 5, GS28, and Ykt6 and is implicated in traffic in the early cisternae of the Golgi apparatus

Xu, Y, Martin, S, James, DE, Hong, W

Mol. Biol. Cell 2002
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