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GOSR2 [Golgi membrane]
Stable Identifier
R-HSA-6807755
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Golgi membrane
Synonyms
Membrin, GS27, Golgi SNAP receptor complex member 2, GOSR2_HUMAN
Locations in the PathwayBrowser for interactor UniProt:Q14973 SLC10A1
Expand all
Metabolism of proteins (Homo sapiens)
Post-translational protein modification (Homo sapiens)
Asparagine N-linked glycosylation (Homo sapiens)
Transport to the Golgi and subsequent modification (Homo sapiens)
ER to Golgi Anterograde Transport (Homo sapiens)
COPI-mediated anterograde transport (Homo sapiens)
NSF ATPase activity dissociates cis-SNARE at cis-Golgi (Homo sapiens)
GOSR2 [Golgi membrane] (Homo sapiens)
Vesicle-mediated transport (Homo sapiens)
Membrane Trafficking (Homo sapiens)
ER to Golgi Anterograde Transport (Homo sapiens)
COPI-mediated anterograde transport (Homo sapiens)
NSF ATPase activity dissociates cis-SNARE at cis-Golgi (Homo sapiens)
GOSR2 [Golgi membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:O14653 GOSR2
Gene Names
GOSR2, GS27
Chain
chain:1-212
Reference Genes
BioGPS Gene:9570 GOSR2
COSMIC (genes):GOSR2 GOSR2
CTD Gene:9570 GOSR2
dbSNP Gene:9570 GOSR2
ENSEMBL:ENSG00000108433 GOSR2
HGNC:4431 GOSR2
KEGG Gene (Homo sapiens):9570 GOSR2
Monarch:9570 GOSR2
NCBI Gene:9570 GOSR2
OMIM:604027 GOSR2
UCSC:O14653 GOSR2
Reference Transcript
RefSeq:NM_001012511.2 GOSR2
RefSeq:NM_054022.3 GOSR2
RefSeq:NM_004287.4 GOSR2
Other Identifiers
0004540056
0006510408
11722435_at
11722436_a_at
11722437_a_at
11729397_at
11758870_x_at
16835125
210009_s_at
213144_at
213180_s_at
213206_at
213207_s_at
229255_3p_x_at
229255_x_at
235041_at
3724361
3724362
3724368
3724370
3724371
3724375
3724376
3724377
3724378
3724379
3724380
3724381
3724382
3724383
3724384
3724385
3724386
3724387
3724388
3724389
38619_at
38620_at
48387_at
53614_at
8007904
9570
A_23_P207719
A_24_P108242
A_33_P3279441
GE86718
GE86832
GO:0000139
GO:0000149
GO:0003674
GO:0005484
GO:0005515
GO:0005575
GO:0005622
GO:0005737
GO:0005768
GO:0005783
GO:0005789
GO:0005794
GO:0005829
GO:0006605
GO:0006623
GO:0006810
GO:0006888
GO:0006891
GO:0006896
GO:0006950
GO:0007034
GO:0007165
GO:0008150
GO:0012507
GO:0015031
GO:0016020
GO:0016021
GO:0016192
GO:0022607
GO:0030674
GO:0031201
GO:0031410
GO:0031902
GO:0032991
GO:0033116
GO:0036498
GO:0042147
GO:0043226
GO:0048208
GO:0048280
GO:0061024
GO:0065003
Hs.100651.1.S1_3p_at
Hs.100651.1.S2_3p_a_at
Hs.190151.0.A1_3p_at
Hs.262198.0.A1_3p_x_at
ILMN_1656293
ILMN_1722812
ILMN_1807072
PH_hs_0025245
TC17000603.hg
g12711466_3p_a_at
Participant Of
hasMember
other COG interacting snares [Golgi membrane]
output
NSF ATPase activity dissociates cis-SNARE at cis-Golgi
hasComponent
GOSR1:GOSR2:STX5 [Golgi membrane]
Other forms of this molecule
GOSR2 [endoplasmic reticulum membrane]
GOSR2 [endoplasmic reticulum-Golgi intermediate compartment membrane]
GOSR2 [ER to Golgi transport vesicle membrane]
Inferred To
GOSR2 [Golgi membrane] (Canis familiaris)
GOSR2 [Golgi membrane] (Dictyostelium discoideum)
GOSR2 [Golgi membrane] (Gallus gallus)
GOSR2 [Golgi membrane] (Plasmodium falciparum)
GOSR2 [Golgi membrane] (Sus scrofa)
gosr2 [Golgi membrane] (Danio rerio)
gosr2 [Golgi membrane] (Xenopus tropicalis)
Gosr2 [Golgi membrane] (Mus musculus)
Gosr2 [Golgi membrane] (Rattus norvegicus)
Membrin [Golgi membrane] (Drosophila melanogaster)
BOS1 [Golgi membrane] (Saccharomyces cerevisiae)
bos1 [Golgi membrane] (Schizosaccharomyces pombe)
memb-1 [Golgi membrane] (Caenorhabditis elegans)
Cross References
RefSeq
NP_473363.1
,
NP_001012529.1
,
NP_004278.2
OpenTargets
ENSG00000108433
GeneCards
O14653
HPA
ENSG00000108433-GOSR2
Ensembl
ENSP00000492751
,
ENSP00000492830
,
ENST00000640621
,
ENST00000640051
,
ENSG00000108433
,
ENSP00000225567
,
ENST00000225567
PRO
O14653
Orphanet
20483
PDB
3EG9
Interactors (48)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q12846 STX4
4
STX4 [phagocytic vesicle membrane]
(R-HSA-2029044)
STX4 [plasma membrane]
(R-HSA-181519)
STX4 [cytosol]
(R-HSA-114505)
p-STX4 [cytosol]
(R-HSA-114681)
0.718
6
UniProt:Q8N6L0 KASH5
0.718
6
UniProt:O15155 BET1
3
BET1 [transport vesicle]
(R-HSA-6808719)
BET1 [Golgi membrane]
(R-HSA-6807743)
BET1 [endoplasmic reticulum-Golgi intermediate compartment membrane]
(R-HSA-5688142)
0.696
5
UniProt:Q9NPE6 SPAG4
0.556
3
UniProt:Q53FP2 TM35A
0.556
3
UniProt:Q9GZY8-5 MFF
0.556
3
UniProt:Q8TBP5 F174A
0.556
3
UniProt:Q8TDT2 GP152
0.556
3
UniProt:Q96A25 T106A
0.556
3
UniProt:A8MZ59 LEUTX
0.556
3
UniProt:Q9Y5U9 IR3IP
0.556
3
UniProt:P49447 CY561
0.556
3
UniProt:Q6UW68 TM205
0.556
3
UniProt:O15529 GPR42
0.556
3
UniProt:Q5T0T0 MARH8
0.556
3
UniProt:Q6ZMZ0 RNF19B
1
RNF19B [cytosol]
(R-HSA-975969)
0.556
3
UniProt:Q9H400 LIME1
0.556
3
UniProt:Q3KNW5 SLC10A6
1
SLC10A6 [plasma membrane]
(R-HSA-433091)
0.556
3
UniProt:Q8TED1 GPX8
1
GPX8 [endoplasmic reticulum lumen]
(R-HSA-3341303)
0.556
3
UniProt:Q5SR56 MF14B
0.556
3
UniProt:Q6N075 MFSD5
0.556
3
UniProt:Q9NYP7 ELOVL5
1
ELOVL5 [endoplasmic reticulum membrane]
(R-HSA-548679)
0.556
3
UniProt:P62952 BLCAP
0.556
3
UniProt:Q9BVX2 T106C
0.556
3
UniProt:Q96MV1 TLCD4
0.556
3
UniProt:Q5JX71 F209A
0.556
3
UniProt:Q08AF8 GOG8F
0.556
5
UniProt:P31937 HIBADH
1
HIBADH [mitochondrial matrix]
(R-HSA-70882)
0.556
3
UniProt:Q8N5M9 JAGN1
0.556
3
UniProt:Q9GZR5 ELOVL4
1
ELOVL4 [endoplasmic reticulum membrane]
(R-HSA-548705)
0.556
3
UniProt:Q969F0 FATE1
0.556
3
UniProt:Q0D2H9 GOG8D
0.556
5
UniProt:Q86VR2 RETR3
0.556
3
UniProt:Q13520 AQP6
1
AQP6 [transport vesicle membrane]
(R-HSA-431741)
0.556
3
UniProt:Q8N6Q1 TMC5A
0.556
3
UniProt:Q96DZ7 T4S19
0.556
3
UniProt:Q53TN4 CYBRD1
1
CYBRD1 [plasma membrane]
(R-HSA-917788)
0.556
3
UniProt:Q7Z5B4-5 RIC3
0.556
3
UniProt:Q96BA8 CREB3L1
7
CREB3L1(427-519) [Golgi membrane]
(R-HSA-8874139)
CREB3L1 [Golgi membrane]
(R-HSA-8874155)
CREB3L1(1-426) [Golgi membrane]
(R-HSA-8874153)
CREB3L1 [endoplasmic reticulum membrane]
(R-HSA-8874157)
CREB3L1(1-375) [cytosol]
(R-HSA-8874215)
CREB3L1(376-426) [Golgi membrane]
(R-HSA-8874213)
CREB3L1(1-375) [nucleoplasm]
(R-HSA-8874222)
0.556
5
UniProt:Q8N4V1 MMGT1
1
MMGT1 [Golgi membrane]
(R-HSA-5216137)
0.556
3
UniProt:Q16623 STX1A
6
STX1A [plasma membrane]
(R-HSA-6794231)
STX1A [plasma membrane]
(R-HSA-449128)
STX1A(?-288) [plasma membrane]
(R-HSA-5246518)
STX1A(1-?) [cytosol]
(R-HSA-3065964)
STX1A [cytosol]
(R-HSA-9609866)
STX1A [endoplasmic reticulum membrane]
(R-HSA-9609878)
0.556
6
UniProt:O43752 STX6
2
STX6 [Golgi membrane]
(R-HSA-6811004)
STX6 [trans-Golgi network membrane]
(R-HSA-6811007)
0.556
3
UniProt:Q7Z5P4 HSD17B13
1
HSD17B13 [cytosol]
(R-HSA-8862029)
0.556
3
UniProt:Q15125 EBP
1
EBP [endoplasmic reticulum membrane]
(R-HSA-195697)
0.556
3
UniProt:Q3SXY8 ARL13B
7
PolyUb-Misfolded ARL13B [cytosol]
(R-HSA-9641129)
PolyUb-Misfolded ARL13B [lysosomal lumen]
(R-HSA-9660004)
Ub-Misfolded ARL13B [cytosol]
(R-HSA-9641119)
Misfolded ARL13B [cytosol]
(R-HSA-9640110)
Misfolded ARL13B [cilium]
(R-HSA-9640116)
ARL13B [cilium]
(R-HSA-5618181)
PolyUb-Misfolded ARL13B [late endosome lumen]
(R-HSA-9659986)
0.556
3
UniProt:Q96FA3 PELI1
2
PELI1 [cytosol]
(R-HSA-450696)
p-PELI1 [cytosol]
(R-HSA-450815)
0.556
3
UniProt:Q14973 SLC10A1
1
SLC10A1 [plasma membrane]
(R-HSA-194116)
0.556
3
UniProt:Q13190 STX5
5
STX5 [endoplasmic reticulum membrane]
(R-HSA-5689474)
STX5 [Golgi membrane]
(R-HSA-6807771)
STX5 [endoplasmic reticulum-Golgi intermediate compartment membrane]
(R-HSA-5688157)
STX5 [ER to Golgi transport vesicle membrane]
(R-HSA-5689838)
STX5 [cytosol]
(R-HSA-9613991)
0.556
3
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