Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
LAMP1 [plasma membrane]
Stable Identifier
R-HSA-6806268
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
Lysosome-associated membrane glycoprotein 1, LAMP1_HUMAN
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Innate Immune System (Homo sapiens)
Neutrophil degranulation (Homo sapiens)
Exocytosis of azurophil granule membrane proteins (Homo sapiens)
Azurophil granule membrane proteins [plasma membrane] (Homo sapiens)
LAMP1 [plasma membrane] (Homo sapiens)
Exocytosis of ficolin-rich granule membrane proteins (Homo sapiens)
Ficolin-rich granule membrane proteins [plasma membrane] (Homo sapiens)
LAMP1 [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:P11279 LAMP1
Gene Names
LAMP1
Chain
signal peptide:1-28, chain:29-417
Reference Genes
BioGPS Gene:3916 LAMP1
COSMIC (genes):LAMP1 LAMP1
CTD Gene:3916 LAMP1
dbSNP Gene:3916 LAMP1
ENSEMBL:ENSG00000185896 LAMP1
ENSEMBL_homo_sapiens_GENE:ENSG00000185896.11 LAMP1
HGNC:6499 LAMP1
KEGG Gene (Homo sapiens):3916 LAMP1
Monarch:3916 LAMP1
NCBI Gene:3916 LAMP1
OMIM:153330 LAMP1
UCSC:P11279 LAMP1
Reference Transcript
RefSeq:NM_005561.3 LAMP1
Other Identifiers
11749875_a_at
11753963_x_at
11757529_s_at
16776856
201551_PM_s_at
201551_s_at
201552_PM_at
201552_at
201553_PM_s_at
201553_s_at
213728_PM_at
213728_at
3502571
3502572
3502575
3502576
3502577
3502582
3502583
3502584
3502586
3502587
3502588
3502591
3502592
3502593
3502594
3502595
3502597
3916
39758_f_at
64344_at
7970287
A_14_P117161
A_23_P162846
A_24_P304549
GE62797
GO:0000421
GO:0001618
GO:0002376
GO:0005515
GO:0005576
GO:0005615
GO:0005737
GO:0005764
GO:0005765
GO:0005768
GO:0005770
GO:0005771
GO:0005773
GO:0005829
GO:0005886
GO:0007018
GO:0007040
GO:0007042
GO:0008021
GO:0008200
GO:0009897
GO:0009986
GO:0010008
GO:0012501
GO:0016020
GO:0016192
GO:0019899
GO:0019904
GO:0023052
GO:0031410
GO:0031902
GO:0031982
GO:0035577
GO:0042383
GO:0042470
GO:0043226
GO:0043323
GO:0044194
GO:0044754
GO:0045335
GO:0045954
GO:0046718
GO:0048471
GO:0050821
GO:0061474
GO:0070062
GO:0072594
GO:0090160
GO:0098542
GO:0098772
GO:0101003
GO:0101004
GO:0140507
GO:1902513
HMNXSV003017710
J03263_s_at
J04182_at
PH_hs_0009041
TC13000421.hg
g187178_3p_a_at
g7669500_3p_a_at
g7669500_3p_x_at
Participates
as a member of
Azurophil granule membrane proteins [plasma membrane] (Homo sapiens)
Ficolin-rich granule membrane proteins [plasma membrane] (Homo sapiens)
Other forms of this molecule
LAMP1 [azurophil granule membrane]
LAMP1 [ficolin-1-rich granule membrane]
Inferred To
lamp1 [plasma membrane]
(Xenopus tropicalis)
lamp1a [plasma membrane]
(Danio rerio)
lmp-2 [plasma membrane]
(Caenorhabditis elegans)
LAMP1 [plasma membrane]
(Bos taurus)
LAMP1 [plasma membrane]
(Canis familiaris)
LAMP1 [plasma membrane]
(Gallus gallus)
LAMP1 [plasma membrane]
(Sus scrofa)
Lamp1 [plasma membrane]
(Drosophila melanogaster)
Lamp1 [plasma membrane]
(Mus musculus)
Lamp1 [plasma membrane]
(Rattus norvegicus)
Cross References
RefSeq
NP_005552.3
OpenTargets
ENSG00000185896
GeneCards
P11279
HPA
ENSG00000185896-LAMP1
Ensembl
ENSP00000333298
,
ENSG00000185896
,
ENST00000332556
PRO
P11279
Pharos - Targets
P11279
Orphanet
25568
PDB
8FYF
,
8ATH
,
8FY5
Interactors (3)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:O75084 FZD7
1
FZD7 [plasma membrane]
(R-HSA-517394)
0.527
3
UniProt:Q9Y2Q5 LAMTOR2
5
LAMTOR2 [specific granule membrane]
(R-HSA-6800168)
LAMTOR2 [plasma membrane]
(R-HSA-6806286)
LAMTOR2 [tertiary granule membrane]
(R-HSA-6800165)
LAMTOR2 [endosome membrane]
(R-HSA-5693293)
LAMTOR2 [lysosomal membrane]
(R-HSA-5653583)
0.527
3
UniProt:Q15836 VAMP3
6
VAMP3 [recycling endosome membrane]
(R-HSA-2029063)
VAMP3 [phagocytic vesicle membrane]
(R-HSA-2029013)
VAMP3 [plasma membrane]
(R-HSA-8867599)
VAMP3 [trans-Golgi network membrane]
(R-HSA-6814624)
VAMP3 [transport vesicle]
(R-HSA-6814625)
VAMP3 [clathrin-coated endocytic vesicle membrane]
(R-HSA-8869130)
0.483
4
© 2024
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text