Reactome | SURF4 [plasma membrane]

SURF4 [plasma membrane]

Stable Identifier

R-HSA-6806264

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

Surfeit locus protein 4, SURF4_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:O15260 SURF4

Gene Names

SURF4, SURF-4

Chain

initiator methionine:1, chain:2-269

Reference Genes

BioGPS Gene:6836 SURF4

COSMIC (genes):SURF4 SURF4

CTD Gene:6836 SURF4

dbSNP Gene:6836 SURF4

ENSEMBL:ENSG00000148248 SURF4

ENSEMBL:ENSG00000280951 SURF4

HGNC:11476 SURF4

KEGG Gene (Homo sapiens):6836 SURF4

Monarch:6836 SURF4

NCBI Gene:6836 SURF4

OMIM:185660 SURF4

UCSC:O15260 SURF4

Reference Transcript

Other Identifiers

0002340253

11715831_s_at

11715832_s_at

11748521_a_at

11749316_a_at

11750020_s_at

11750021_x_at

17099512

222977_at

222978_at

222979_s_at

3228675

3228676

3228677

3228678

3228679

3228682

3228683

3228685

3228687

3228688

3228697

3228698

4051967

4051968

4051969

4051970

4051971

4051974

4051975

4051977

4051979

4051980

4051991

4051992

65743_at

6836

8164883

A_23_P32052

A_24_P89971

A_33_P3222783

GE79637

GO:0000139

GO:0002376

GO:0003674

GO:0005515

GO:0005575

GO:0005622

GO:0005737

GO:0005764

GO:0005773

GO:0005783

GO:0005789

GO:0005793

GO:0005794

GO:0005829

GO:0005886

GO:0006810

GO:0006890

GO:0007030

GO:0008150

GO:0010638

GO:0016020

GO:0016021

GO:0016192

GO:0030133

GO:0031410

GO:0033116

GO:0035577

GO:0043226

GO:0043312

HMNXSV003012161

Hs.284296.0.A3_3p_at

ILMN_1690761

ILMN_1799055

PH_hs_0014739

g5531846_3p_a_at

Participates

as a member of

Azurophil granule membrane proteins [plasma membrane] (Homo sapiens)

Other forms of this molecule

SURF4 [Golgi membrane]

SURF4 [transport vesicle]

SURF4 [endoplasmic reticulum membrane]

SURF4 [azurophil granule membrane]

Inferred To

SURF4 [plasma membrane] (Canis familiaris)

SURF4 [plasma membrane] (Gallus gallus)

SURF4 [plasma membrane] (Plasmodium falciparum)

SURF4 [plasma membrane] (Schizosaccharomyces pombe)

SURF4 [plasma membrane] (Sus scrofa)

surf1-2 [plasma membrane] (Dictyostelium discoideum)

sft-4 [plasma membrane] (Caenorhabditis elegans)

Surf4 [plasma membrane] (Drosophila melanogaster)

Surf4 [plasma membrane] (Mus musculus)

Surf4 [plasma membrane] (Rattus norvegicus)

ERV29 [plasma membrane] (Saccharomyces cerevisiae)

surf4 [plasma membrane] (Danio rerio)

Cross References

RefSeq

NP_001267721.1, NP_001267718.1, NP_149351.1

Target Pathogen

5b354852be737e166372ebd0

OpenTargets

ENSG00000148248

HPA

ENSG00000148248-SURF4

GeneCards

O15260

Ensembl

ENST00000629119, ENSP00000419853, ENSG00000148248, ENST00000626303, ENST00000545297, ENST00000371989, ENSP00000361057, ENSP00000446061, ENST00000629578, ENSP00000487537, ENSP00000486049, ENSP00000486869, ENSG00000280951, ENST00000485435

PRO

O15260

Interactors (3)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q86WV6 STING1	5	K63polyUb-STING [endoplasmic reticulum membrane] (R-HSA-3134805) K63polyUb-STING [cytoplasmic vesicle membrane] (R-HSA-3248021) STING [endoplasmic reticulum membrane] (R-HSA-1834940) TMEM173 [plasma membrane] (R-HSA-6804815) TMEM173 [secretory granule membrane] (R-HSA-6804798)	0.623	3
UniProt:Q15363 TMED2	5	TMED2 [endoplasmic reticulum membrane] (R-HSA-5689480) TMED2 [ER to Golgi transport vesicle membrane] (R-HSA-5689847) TMED2 [transport vesicle] (R-HSA-6808806) TMED2 [Golgi membrane] (R-HSA-6808804) TMED2 [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-HSA-1911531)	0.558	3
UniProt:Q8VCW4	2	Unc93b1 [Golgi membrane] (R-MMU-1679064) Unc93b1 [endoplasmic reticulum membrane] (R-MMU-1678930)	0.499	2

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