Reactome | SURF4 [plasma membrane]

SURF4 [plasma membrane]

Stable Identifier

R-HSA-6806264

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

Surfeit locus protein 4, SURF4_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:O15260 SURF4

Gene Names

SURF4, SURF-4

Chain

initiator methionine:, chain:2-269

Reference Genes

BioGPS Gene:6836 SURF4

COSMIC (genes):SURF4 SURF4

CTD Gene:6836 SURF4

dbSNP Gene:6836 SURF4

ENSEMBL:ENSG00000148248 SURF4

HGNC:11476 SURF4

KEGG:hsa:6836 SURF4

Monarch:6836 SURF4

NCBI Gene:6836 SURF4

OMIM:185660 SURF4

UCSC:O15260 SURF4

Reference Transcript

Other Identifiers

11715831_s_at

11715832_s_at

11748521_a_at

11749316_a_at

11750020_s_at

11750021_x_at

17099512

222977_PM_at

222977_at

222978_PM_at

222978_at

222979_PM_s_at

222979_s_at

3228675

3228676

3228677

3228678

3228679

3228680

3228681

3228682

3228683

3228685

3228686

3228687

3228688

3228689

3228697

3228698

4051967

4051968

4051969

4051970

4051971

4051972

4051973

4051974

4051975

4051977

4051978

4051979

4051980

4051981

4051991

4051992

65743_at

6836

8164883

A_23_P32052

A_24_P89971

A_33_P3222783

GE79637

GO:0000139

GO:0005515

GO:0005783

GO:0005789

GO:0005793

GO:0005794

GO:0005829

GO:0005886

GO:0006888

GO:0007030

GO:0010638

GO:0015031

GO:0016020

GO:0016192

GO:0030133

GO:0030134

GO:0031410

GO:0031965

GO:0032368

GO:0033116

GO:0035577

GO:0038024

GO:0042953

GO:0043226

GO:0055088

GO:0070971

GO:0090110

GO:0097020

GO:0140353

HMNXSV003012161

Hs.284296.0.A3_3p_at

ILMN_1690761

PH_hs_0014739

TC09001688.hg

g5531846_3p_a_at

Participates

as a member of

Azurophil granule membrane proteins [plasma membrane] (Homo sapiens)

Other forms of this molecule

SURF4 [Golgi membrane]

SURF4 [transport vesicle]

SURF4 [endoplasmic reticulum membrane]

SURF4 [azurophil granule membrane]

Inferred To

SURF4 [plasma membrane] (Bos taurus)

SURF4 [plasma membrane] (Canis familiaris)

SURF4 [plasma membrane] (Gallus gallus)

SURF4 [plasma membrane] (Schizosaccharomyces pombe)

SURF4 [plasma membrane] (Sus scrofa)

sft-4 [plasma membrane] (Caenorhabditis elegans)

Surf4 [plasma membrane] (Drosophila melanogaster)

Surf4 [plasma membrane] (Mus musculus)

ERV29 [plasma membrane] (Saccharomyces cerevisiae)

surf4.2 [plasma membrane] (Xenopus tropicalis)

surf4 [plasma membrane] (Danio rerio)

Cross References

RefSeq

NP_149351.1, NP_001267721.1, NP_001267718.1

ENSEMBL

ENSG00000148248, ENST00000545297, ENSG00000280951, ENSP00000361057, ENSP00000487537, ENSP00000486869, ENST00000485435, ENST00000629119, ENSP00000486049, ENST00000626303, ENSP00000419853, ENST00000371989, ENSP00000446061, ENST00000629578

OpenTargets

ENSG00000148248

GeneCards

SURF4

HPA

ENSG00000148248-SURF4

PRO

O15260

Pharos - Targets

O15260

GlyGen

O15260

Interactors (4)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q15363 TMED2	5	TMED2 [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-HSA-1911531) TMED2 [endoplasmic reticulum membrane] (R-HSA-5689480) TMED2 [ER to Golgi transport vesicle membrane] (R-HSA-5689847) TMED2 [transport vesicle] (R-HSA-6808806) TMED2 [Golgi membrane] (R-HSA-6808804)	0.662	4
UniProt:Q86WV6 STING1	5	STING [endoplasmic reticulum membrane] (R-HSA-1834940) TMEM173 [secretory granule membrane] (R-HSA-6804798) TMEM173 [plasma membrane] (R-HSA-6804815) K63polyUb-STING [cytoplasmic vesicle membrane] (R-HSA-3248021) K63polyUb-STING [endoplasmic reticulum membrane] (R-HSA-3134805)	0.623	3
UniProt:P13569 CFTR	17	misfolded CFTR [endoplasmic reticulum membrane] (R-HSA-8868730) CFTR [endoplasmic reticulum membrane] (R-HSA-8866837) CFTR [plasma membrane] (R-HSA-383188) CFTR N1303K [plasma membrane] (R-HSA-5678983) CFTR F508del [plasma membrane] (R-HSA-5678978) CFTR W1282* [plasma membrane] (R-HSA-5678976) CFTR G551D [plasma membrane] (R-HSA-5678977) CFTR G542* [plasma membrane] (R-HSA-5678986) ub-CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866842) ub-CFTR F508del [cytosol] (R-HSA-8866838) CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866834) PolyUb-CFTR [endosome membrane] (R-HSA-6782976) CFTR [endosome membrane] (R-HSA-6782965) CFTR [Golgi-associated vesicle membrane] (R-HSA-5627079) CFTR [lysosomal membrane] (R-HSA-5627279) PolyUb-CFTR [plasma membrane] (R-HSA-8867595) PolyUb-CFTR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869104)	0.548	12
UniProt:Q8VCW4	2	Unc93b1 [endoplasmic reticulum membrane] (R-MMU-1678930) Unc93b1 [Golgi membrane] (R-MMU-1679064)	0.499	2

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