Reactome | SNAP23 [specific granule membrane]

SNAP23 [specific granule membrane]

Stable Identifier

R-HSA-6806157

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

specific granule membrane

Synonyms

Synaptosomal-associated protein 23, SNP23_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:O00161 SNAP23

Gene Names

SNAP23

Chain

chain:1-211

Reference Genes

BioGPS Gene:8773 SNAP23

COSMIC (genes):SNAP23 SNAP23

CTD Gene:8773 SNAP23

dbSNP Gene:8773 SNAP23

ENSEMBL:ENSG00000092531 SNAP23

HGNC:11131 SNAP23

KEGG:hsa:8773 SNAP23

Monarch:8773 SNAP23

NCBI Gene:8773 SNAP23

OMIM:602534 SNAP23

UCSC:O00161 SNAP23

Reference Transcript

Other Identifiers

11739173_a_at

11739174_x_at

11741581_s_at

11753568_x_at

11757831_x_at

16800095

209130_PM_at

209130_at

209131_PM_s_at

209131_s_at

214544_PM_s_at

214544_s_at

229773_PM_at

229773_at

32178_r_at

32179_s_at

3591007

3591008

3591009

3591010

3591012

3591013

3591014

3591015

3591016

3591017

3591018

3591019

3591020

3591023

3591024

3591027

3591028

3591029

3591030

3591031

3591032

3591033

3591034

3591039

3591040

3591041

46749_i_at

7983111

8773

88736_at

A_14_P120636

A_23_P206177

A_33_P3305974

GE564662

GE81326

GO:0002553

GO:0005484

GO:0005515

GO:0005654

GO:0005737

GO:0005739

GO:0005764

GO:0005773

GO:0005886

GO:0005912

GO:0005925

GO:0006887

GO:0006892

GO:0006903

GO:0015031

GO:0016020

GO:0016082

GO:0016192

GO:0017075

GO:0019905

GO:0030670

GO:0031201

GO:0031410

GO:0031629

GO:0035579

GO:0042581

GO:0042582

GO:0043005

GO:0043226

GO:0045202

GO:0060090

GO:0061024

GO:0061025

GO:0065003

GO:0070032

GO:0070062

GO:0070821

GO:0098793

HMNXSV003029186

Hs.122505.0.A1_3p_at

ILMN_1687519

ILMN_1748911

PH_hs_0023005

TC15000320.hg

U55936_at

g13277555_3p_at

g1374812_3p_a_at

Participates

as a member of

Specific granule membrane proteins [specific granule membrane] (Homo sapiens)

Other forms of this molecule

p-S95-SNAP23 [phagocytic vesicle membrane]

SNAP23 [phagocytic vesicle membrane]

SNAP23 [tertiary granule membrane]

SNAP23 [plasma membrane]

Inferred To

Snap23 [specific granule membrane] (Mus musculus)

Snap23 [specific granule membrane] (Rattus norvegicus)

Snap24 [specific granule membrane] (Drosophila melanogaster)

Snap25 [specific granule membrane] (Drosophila melanogaster)

SEC9 [specific granule membrane] (Saccharomyces cerevisiae)

aex-4 [specific granule membrane] (Caenorhabditis elegans)

SNAP23 [specific granule membrane] (Bos taurus)

SNAP23 [specific granule membrane] (Canis familiaris)

SNAP23 [specific granule membrane] (Dictyostelium discoideum)

SNAP23 [specific granule membrane] (Gallus gallus)

SNAP23 [specific granule membrane] (Plasmodium falciparum)

SNAP23 [specific granule membrane] (Sus scrofa)

SPO20 [specific granule membrane] (Saccharomyces cerevisiae)

snap23 [specific granule membrane] (Xenopus tropicalis)

cspA [specific granule membrane] (Dictyostelium discoideum)

ric-4 [specific granule membrane] (Caenorhabditis elegans)

sec9 [specific granule membrane] (Schizosaccharomyces pombe)

Homologues of SNAP23 [specific granule membrane] (Caenorhabditis elegans)

Homologues of SNAP23 [specific granule membrane] (Dictyostelium discoideum)

Homologues of SNAP23 [specific granule membrane] (Drosophila melanogaster)

Homologues of SNAP23 [specific granule membrane] (Saccharomyces cerevisiae)

Cross References

ENSEMBL

ENST00000397138, ENSP00000380327, ENST00000349777, ENSP00000207062, ENST00000249647, ENSP00000249647

OpenTargets

ENSG00000092531

HPA

ENSG00000092531-SNAP23

PRO

O00161

Pharos - Targets

O00161

GlyGen

O00161

PDB

1NHL, 3ZUS

Interactors (13)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:O75558 STX11			0.871	11
UniProt:P54920 NAPA	1	NAPA [cytosol] (R-HSA-264469)	0.779	5
UniProt:Q15836 VAMP3	6	VAMP3 [recycling endosome membrane] (R-HSA-2029063) VAMP3 [phagocytic vesicle membrane] (R-HSA-2029013) VAMP3 [plasma membrane] (R-HSA-8867599) VAMP3 [trans-Golgi network membrane] (R-HSA-6814624) VAMP3 [transport vesicle] (R-HSA-6814625) VAMP3 [clathrin-coated endocytic vesicle membrane] (R-HSA-8869130)	0.669	3
UniProt:Q9H115 NAPB	1	NAPB [cytosol] (R-HSA-5688553)	0.556	3
UniProt:Q16623 STX1A	5	STX1A [plasma membrane] (R-HSA-449128) STX1A(?-288) [plasma membrane] (R-HSA-5246518) STX1A(1-?) [cytosol] (R-HSA-3065964) STX1A [cytosol] (R-HSA-9609866) STX1A [endoplasmic reticulum membrane] (R-HSA-9609878)	0.553	2
UniProt:O76038 SEGN			0.547	3
UniProt:Q13277 STX3	1	STX3 [plasma membrane] (R-HSA-449131)	0.547	2
UniProt:O95183 VAMP5			0.527	2
UniProt:O15400 STX7			0.527	4
UniProt:Q86Y82 STX12			0.527	4
UniProt:Q8IUH5 ZDH17			0.508	4
UniProt:P13569 CFTR	17	misfolded CFTR [endoplasmic reticulum membrane] (R-HSA-8868730) CFTR [endoplasmic reticulum membrane] (R-HSA-8866837) CFTR [plasma membrane] (R-HSA-383188) CFTR N1303K [plasma membrane] (R-HSA-5678983) CFTR F508del [plasma membrane] (R-HSA-5678978) CFTR W1282* [plasma membrane] (R-HSA-5678976) CFTR G551D [plasma membrane] (R-HSA-5678977) CFTR G542* [plasma membrane] (R-HSA-5678986) ub-CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866842) ub-CFTR F508del [cytosol] (R-HSA-8866838) CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866834) PolyUb-CFTR [endosome membrane] (R-HSA-6782976) CFTR [endosome membrane] (R-HSA-6782965) CFTR [Golgi-associated vesicle membrane] (R-HSA-5627079) CFTR [lysosomal membrane] (R-HSA-5627279) PolyUb-CFTR [plasma membrane] (R-HSA-8867595) PolyUb-CFTR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869104)	0.483	7
UniProt:P56962 STX17	1	STX17 [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-HSA-6807769)	0.471	2

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