Reactome | GPR150 [plasma membrane]

GPR150 [plasma membrane]

Stable Identifier

R-HSA-6805218

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

Probable G-protein coupled receptor 150, GP150_HUMAN

Locations in the PathwayBrowser

Expand all

Signal Transduction (Homo sapiens)

- Signaling by GPCR (Homo sapiens)
  - GPCR downstream signalling (Homo sapiens)
    - G alpha (s) signalling events (Homo sapiens)
      - Liganded Gs-activating GPCR acts as a GEF for Gs (Homo sapiens)
        
        GPCR:ligand complexes that act on Gs:Heterotrimeric G-protein Gs (active) [plasma membrane] (Homo sapiens)
        
        Ligand:GPCR complexes that activate Gs [plasma membrane] (Homo sapiens)
        
        Constitutively active orphan GPCRs [plasma membrane] (Homo sapiens)
        
        GPR150 [plasma membrane] (Homo sapiens)
        
        Ligand:GPCR complexes that activate Gs:Heterotrimeric G-protein Gs (inactive) [plasma membrane] (Homo sapiens)
        
        Ligand:GPCR complexes that activate Gs [plasma membrane] (Homo sapiens)
        
        Constitutively active orphan GPCRs [plasma membrane] (Homo sapiens)
        
        GPR150 [plasma membrane] (Homo sapiens)
      - Liganded Gs-activating GPCRs bind inactive heterotrimeric Gs (Homo sapiens)
        
        Ligand:GPCR complexes that activate Gs [plasma membrane] (Homo sapiens)
        
        Constitutively active orphan GPCRs [plasma membrane] (Homo sapiens)
        
        GPR150 [plasma membrane] (Homo sapiens)
        
        Ligand:GPCR complexes that activate Gs:Heterotrimeric G-protein Gs (inactive) [plasma membrane] (Homo sapiens)
        
        Ligand:GPCR complexes that activate Gs [plasma membrane] (Homo sapiens)
        
        Constitutively active orphan GPCRs [plasma membrane] (Homo sapiens)
        
        GPR150 [plasma membrane] (Homo sapiens)
      - The Ligand:GPCR:Gs complex dissociates (Homo sapiens)
        
        GPCR:ligand complexes that act on Gs:Heterotrimeric G-protein Gs (active) [plasma membrane] (Homo sapiens)
        
        Ligand:GPCR complexes that activate Gs [plasma membrane] (Homo sapiens)
        
        Constitutively active orphan GPCRs [plasma membrane] (Homo sapiens)
        
        GPR150 [plasma membrane] (Homo sapiens)
        
        GPCRs that activate Gs [plasma membrane] (Homo sapiens)
        
        Constitutively active orphan GPCRs [plasma membrane] (Homo sapiens)
        
        GPR150 [plasma membrane] (Homo sapiens)

External Reference Information

External Reference

UniProt:Q8NGU9 GPR150

Gene Names

GPR150

Chain

chain:1-434

Reference Genes

BioGPS Gene:285601 GPR150

COSMIC (genes):GPR150 GPR150

CTD Gene:285601 GPR150

dbSNP Gene:285601 GPR150

ENSEMBL:ENSG00000178015.5 GPR150

HGNC:23628 GPR150

KEGG Gene (Homo sapiens):285601 GPR150

Monarch:285601 GPR150

NCBI Gene:285601 GPR150

UCSC:Q8NGU9 GPR150

Reference Transcript

RefSeq:NM_199243.1 GPR150

Other Identifiers

11742134_at

16987377

2820885

2820886

2820887

2820888

2820889

2820890

2820891

2820892

285601

8106976

ADDON000028.hg

A_23_P213527

A_24_P37887

GE502719

GO:0004930

GO:0005886

GO:0007165

GO:0007186

GO:0016020

GO:0016021

GO:0023052

GO:0042277

GO:0060089

HMNXSV003039569

ILMN_1708428

PH_hs_0039963

TC05000459.hg

TC05002518.hg

Participates

as a member of

Constitutively active orphan GPCRs [plasma membrane] (Homo sapiens)

Inferred To

Gpr150 [plasma membrane] (Mus musculus)

Gpr150 [plasma membrane] (Rattus norvegicus)

GPR150 [plasma membrane] (Sus scrofa)

gnrr-1 [plasma membrane] (Caenorhabditis elegans)

AkhR [plasma membrane] (Drosophila melanogaster)

Cross References

RefSeq

NP_954713.1

Guide to Pharmacology - Targets

136

OpenTargets

ENSG00000178015

HPA

ENSG00000178015-GPR150

GeneCards

Q8NGU9

Ensembl

ENSP00000369344, ENSG00000178015, ENST00000380007

PRO

Q8NGU9

Pharos - Targets

Q8NGU9