Reactome | CFD [secretory granule lumen]

CFD [secretory granule lumen]

Stable Identifier

R-HSA-6804805

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

secretory granule lumen

Synonyms

Complement factor D precursor , C3 convertase activator, Properdin factor D, Adipsin

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External Reference Information

External Reference

UniProt:P00746 CFD

Gene Names

CFD, DF, PFD

Chain

signal peptide:1-20, propeptide:21-25, chain:26-253

Reference Genes

BioGPS Gene:1675 CFD

COSMIC (genes):CFD CFD

CTD Gene:1675 CFD

dbSNP Gene:1675 CFD

ENSEMBL:ENSG00000197766 CFD

HGNC:2771 CFD

KEGG:hsa:1675 CFD

Monarch:1675 CFD

NCBI Gene:1675 CFD

OMIM:134350 CFD

UCSC:P00746 CFD

Reference Transcript

Other Identifiers

11725980_at

1675

16856299

205382_PM_s_at

205382_s_at

3815244

3815245

3815246

3815247

3815248

3815249

3815251

3815252

3815253

3815254

3815255

3815257

40282_s_at

8024062

A_14_P124724

A_23_P119562

GE81088

GO:0002376

GO:0003824

GO:0004252

GO:0005576

GO:0005615

GO:0006508

GO:0006956

GO:0006957

GO:0008236

GO:0009617

GO:0016787

GO:0031093

GO:0034774

GO:0043226

GO:0070062

GO:0098542

GO:0140096

GO:1904813

HMNXSV003001420

ILMN_1777190

M84526_at

PH_hs_0029251

TC19000020.hg

g4503308_3p_at

Participates

as a member of

Secretory granule lumen proteins [secretory granule lumen] (Homo sapiens)

Other forms of this molecule

CFD [extracellular region]

CFD [ficolin-1-rich granule lumen]

CFD [platelet alpha granule lumen]

Inferred To

CFD [secretory granule lumen] (Bos taurus)

CFD [secretory granule lumen] (Canis familiaris)

CFD [secretory granule lumen] (Gallus gallus)

CFD [secretory granule lumen] (Sus scrofa)

ami [secretory granule lumen] (Xenopus tropicalis)

cfd [secretory granule lumen] (Danio rerio)

Cfd [secretory granule lumen] (Mus musculus)

Cfd [secretory granule lumen] (Rattus norvegicus)

Cross References

RefSeq

NP_001919.2, NP_001304264.1

Guide to Pharmacology - Targets

2842

OpenTargets

ENSG00000197766

ENSEMBL

ENSP00000478745, ENST00000327726, ENST00000617994, ENSP00000332139

HPA

ENSG00000197766-CFD

ZINC - Substances

CFAD_HUMAN

ZINC target

P00746

PRO

P00746

Pharos - Targets

P00746

Orphanet

CFD

ZINC - Predictions - Purchasable

CFAD_HUMAN

PDB

4CBN, 6FTZ, 4CBO, 1DIC, 5TCA, 1DST, 1DSU, 5TCC, 5MT4, 5FCK, 5MT0, 6FTY, 8DG6, 8D95, 5NAR, 8DEA, 6FUG, 6FUH, 2XWA, 2XW9, 6VMJ, 6FUT, 5NB7, 1FDP, 6VMK, 6QMT, 4D9R, 1HFD, 2XWB, 1BIO, 5FBI, 5NB6, 1DFP, 5NAT, 6FUI, 6FUJ, 5NBA, 5FBE, 5NAW, 6QMR

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