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FCGR2A [secretory granule membrane]
Stable Identifier
R-HSA-6804791
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
secretory granule membrane
Synonyms
Low affinity immunoglobulin gamma Fc region receptor II-a, FCGA_HUMAN
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Innate Immune System (Homo sapiens)
Neutrophil degranulation (Homo sapiens)
Exocytosis of secretory granule membrane proteins (Homo sapiens)
Secretory granule membrane proteins [secretory granule membrane] (Homo sapiens)
FCGR2A [secretory granule membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:P12318 FCGR2A
Gene Names
FCGR2A, CD32, FCG2, FCGR2A1, IGFR2
Chain
signal peptide:1-33, chain:34-317
Reference Genes
BioGPS Gene:2212 FCGR2A
COSMIC (genes):FCGR2A FCGR2A
CTD Gene:2212 FCGR2A
dbSNP Gene:2212 FCGR2A
ENSEMBL:ENSG00000143226 FCGR2A
HGNC:3616 FCGR2A
KEGG Gene (Homo sapiens):2212 FCGR2A
Monarch:2212 FCGR2A
NCBI Gene:2212 FCGR2A
OMIM:146790 FCGR2A
UCSC:P12318 FCGR2A
Reference Transcript
RefSeq:NM_021642.3 FCGR2A
RefSeq:NM_001136219.1 FCGR2A
Other Identifiers
0002350082
11724768_s_at
11724769_x_at
11724770_s_at
11724771_x_at
11749587_x_at
11751242_s_at
203561_at
210992_x_at
2212
2363739
2363740
2363745
2363750
2363754
2363759
2363763
2363764
2363765
2363766
2363767
2363768
2363769
2363770
2363771
2363772
2363773
2363774
2363775
2363776
2363777
2363829
2363833
34665_g_at
37687_i_at
37688_f_at
37689_s_at
7906757
A_23_P85716
A_33_P3403576
GE57930
GO:0002376
GO:0002862
GO:0003674
GO:0004888
GO:0005515
GO:0005575
GO:0005622
GO:0005737
GO:0005794
GO:0005886
GO:0005887
GO:0006810
GO:0006950
GO:0007165
GO:0007166
GO:0008150
GO:0016020
GO:0016021
GO:0016192
GO:0019864
GO:0030667
GO:0031410
GO:0038096
GO:0043226
GO:0043312
GO:0050776
HMNXSV003019097
ILMN_1666932
ILMN_1704776
ILMN_1706523
ILMN_2289849
M31932_at
PH_hs_0023950
PH_hs_0032813
X68090_s_at
g11056051_3p_at
g11056051_3p_x_at
g2149627_3p_a_at
g2149627_3p_s_at
Participates
as a member of
Secretory granule membrane proteins [secretory granule membrane] (Homo sapiens)
Other forms of this molecule
FCGR2A [plasma membrane]
p-Y288,Y304-FCGR2A [plasma membrane]
Inferred To
si:ch211-286b5.6 [secretory granule membrane]
(Danio rerio)
LOC100494132 [secretory granule membrane]
(Xenopus tropicalis)
si:ch211-220f21.2 [secretory granule membrane]
(Danio rerio)
FCGR2B [secretory granule membrane]
(Bos taurus)
si:ch73-368j24.17 [secretory granule membrane]
(Danio rerio)
si:dkey-10h3.7 [secretory granule membrane]
(Danio rerio)
LOC110260307 [secretory granule membrane]
(Sus scrofa)
si:ch1073-66l23.1 [secretory granule membrane]
(Danio rerio)
zmp:0000001139 [secretory granule membrane]
(Danio rerio)
si:cabz01036022.1 [secretory granule membrane]
(Danio rerio)
LOC105945518 [secretory granule membrane]
(Xenopus tropicalis)
si:ch211-220f21.1 [secretory granule membrane]
(Danio rerio)
LOC101886098 [secretory granule membrane]
(Danio rerio)
XB5991222 [provisional:fcrl3] [secretory granule membrane]
(Xenopus tropicalis)
LOC100856270 [secretory granule membrane]
(Canis familiaris)
si:ch211-165f21.2 [secretory granule membrane]
(Danio rerio)
upk2 [secretory granule membrane]
(Xenopus tropicalis)
si:dkey-10h3.3 [secretory granule membrane]
(Danio rerio)
Homologues of FCGR2A [secretory granule membrane]
(Danio rerio)
Homologues of FCGR2A [secretory granule membrane]
(Gallus gallus)
Homologues of FCGR2A [secretory granule membrane]
(Xenopus tropicalis)
si:ch211-163c2.2 [secretory granule membrane]
(Danio rerio)
si:ch211-165f21.7 [secretory granule membrane]
(Danio rerio)
si:ch211-220f21.3 [secretory granule membrane]
(Danio rerio)
unc-89 [secretory granule membrane]
(Caenorhabditis elegans)
FCGR2A [secretory granule membrane]
(Danio rerio)
FCGR2A [secretory granule membrane]
(Xenopus tropicalis)
si:dkey-10h3.2 [secretory granule membrane]
(Danio rerio)
LOC101748032 [secretory granule membrane]
(Gallus gallus)
Fcgr2 [secretory granule membrane]
(Mus musculus)
Fcgr2 [secretory granule membrane]
(Rattus norvegicus)
FCRL4 [secretory granule membrane]
(Gallus gallus)
si:dkey-23a13.11 [secretory granule membrane]
(Danio rerio)
si:dkey-23a13.2 [secretory granule membrane]
(Danio rerio)
Cross References
RefSeq
NP_001129691.1
,
NP_067674.2
Guide to Pharmacology - Targets
3190
OpenTargets
ENSG00000143226
HPA
ENSG00000143226-FCGR2A
GeneCards
P12318
ZINC target
P12318
Ensembl
ENSG00000143226
,
ENST00000271450
,
ENST00000367972
,
ENSP00000271450
,
ENSP00000356949
PRO
P12318
Pharos - Targets
P12318
GlyGen
P12318
PDB
1FCG
,
1H9V
,
3RY6
,
3RY4
,
3RY5
,
3D5O
Interactors (2)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q9UMX0 UBQLN1
1
UBQLN1 [cytosol]
(R-HSA-8866006)
0.556
3
UniProt:Q9UMX0-2 UBQLN1
0.556
3
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