Reactome | C5AR1 [secretory granule membrane]

C5AR1 [secretory granule membrane]

Stable Identifier

R-HSA-6804785

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

secretory granule membrane

Synonyms

C5a anaphylatoxin chemotactic receptor, C5AR_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:P21730 C5AR1

Gene Names

C5AR1, C5AR, C5R1

Chain

chain:1-350

Reference Genes

BioGPS Gene:728 C5AR1

COSMIC (genes):C5AR1 C5AR1

CTD Gene:728 C5AR1

dbSNP Gene:728 C5AR1

ENSEMBL:ENSG00000197405 C5AR1

HGNC:1338 C5AR1

KEGG:hsa:728 C5AR1

Monarch:728 C5AR1

NCBI Gene:728 C5AR1

OMIM:113995 C5AR1

UCSC:P21730 C5AR1

Reference Transcript

Other Identifiers

11733355_x_at

11733356_at

16863589

220088_PM_at

220088_at

3837256

3837258

3837260

3837261

3837262

3837263

3837264

728

8029907

A_14_P131510

A_23_P153562

A_23_P303058

GE80070

GO:0001774

GO:0002376

GO:0002430

GO:0002682

GO:0004875

GO:0004878

GO:0004930

GO:0005886

GO:0006351

GO:0006935

GO:0006954

GO:0006955

GO:0006968

GO:0007165

GO:0007186

GO:0007200

GO:0007204

GO:0007606

GO:0010575

GO:0010759

GO:0016020

GO:0016071

GO:0016323

GO:0030593

GO:0030667

GO:0031410

GO:0032494

GO:0038178

GO:0042789

GO:0043226

GO:0045177

GO:0045766

GO:0048143

GO:0048870

GO:0050679

GO:0050830

GO:0050877

GO:0050890

GO:0060089

GO:0070374

GO:0090023

GO:0097242

GO:0098542

GO:0099172

HMNXSV003056825

ILMN_1689836

M62505_at

PH_hs_0030878

TC19000676.hg

g4502508_3p_at

Participates

as a member of

Secretory granule membrane proteins [secretory granule membrane] (Homo sapiens)

Other forms of this molecule

C5AR1 [plasma membrane]

Inferred To

c3ar1 [secretory granule membrane] (Xenopus tropicalis)

C5AR1 [secretory granule membrane] (Bos taurus)

C5AR1 [secretory granule membrane] (Canis familiaris)

C5AR1 [secretory granule membrane] (Gallus gallus)

C5AR1 [secretory granule membrane] (Sus scrofa)

C5ar1 [secretory granule membrane] (Mus musculus)

C5ar1 [secretory granule membrane] (Rattus norvegicus)

Cross References

RefSeq

NP_001727.1, NP_001727.2

Guide to Pharmacology - Targets

OpenTargets

ENSG00000197405

ENSEMBL

ENST00000355085, ENSG00000197405, ENSP00000347197

ZINC - Substances

C5AR1_HUMAN

ZINC target

P21730

PRO

P21730

GlyGen

P21730

PDB

8I0Z, 2K3U, 7Y64, 8JZZ, 8HK5, 7Y67, 8I0N, 7Y66, 7Y65, 5O9H, 8GO8, 8IA2, 6C1Q, 8GOO, 6C1R

ZINC - Investigational

C5AR1_HUMAN

HPA

ENSG00000197405-C5AR1

GeneCards

C5AR1

Pharos - Targets

P21730

ZINC - Predictions - Purchasable

C5AR1_HUMAN

HMDB Protein

HMDBP07483

Interactors (3)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q5HYI8 RABL3			0.527	2
UniProt:Q9H4A6 GOLP3			0.527	2
UniProt:P18031 PTPN1	2	PTPN1 [endosome membrane] (R-HSA-9815895) PTPN1 [cytosol] (R-HSA-210625)	0.527	3

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