Reactome | PRDM1 binds the TP53 gene

PRDM1 binds the TP53 gene

Stable Identifier

R-HSA-6804194

Type

Reaction [binding]

Species

Homo sapiens

Compartment

nucleoplasm

Locations in the PathwayBrowser

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Gene expression (Transcription) (Homo sapiens)

- RNA Polymerase II Transcription (Homo sapiens)
  - Generic Transcription Pathway (Homo sapiens)
    - Transcriptional Regulation by TP53 (Homo sapiens)
      - Regulation of TP53 Activity (Homo sapiens)
        
        Regulation of TP53 Expression and Degradation (Homo sapiens)
        
        Regulation of TP53 Expression (Homo sapiens)
        
        PRDM1 binds the TP53 gene (Homo sapiens)

General

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PRDM1 (BLIMP1) zinc finger transcription factor binds in vicinity of the transcription start site of the TP53 (p53) gene (Yan et al. 2007).

Literature References

PubMed ID	Title	Journal	Year
17264218	BLIMP1 regulates cell growth through repression of p53 transcription Yan, J, Jiang, J, Lim, CA, Wu, Q, Ng, HH, Chin, KC	Proc. Natl. Acad. Sci. U.S.A.	2007

Participants

Input

Output

PRDM1:TP53 Gene [nucleoplasm] (Homo sapiens)

Participant Of

hasEvent

Regulation of TP53 Expression

Authored

Orlic-Milacic, M (2015-10-14)

Reviewed

Zaccara, S (2016-02-04)

Inga, A (2016-02-04)

Created

Orlic-Milacic, M (2015-10-09)