Reactome | TP53 stimulates PRDM1 expression

TP53 stimulates PRDM1 expression

Stable Identifier

R-HSA-6804193

Type

Reaction [omitted]

Species

Homo sapiens

Compartment

nucleoplasm

Locations in the PathwayBrowser

Expand all

Gene expression (Transcription) (Homo sapiens)

- RNA Polymerase II Transcription (Homo sapiens)
  - Generic Transcription Pathway (Homo sapiens)
    - Transcriptional Regulation by TP53 (Homo sapiens)
      - Regulation of TP53 Activity (Homo sapiens)
        
        Regulation of TP53 Expression and Degradation (Homo sapiens)
        
        Regulation of TP53 Expression (Homo sapiens)
        
        TP53 stimulates PRDM1 expression (Homo sapiens)

General

SBML | | PDF

SVG | | PPTX | SBGN

Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout

Binding of TP53 (p53) to the p53 response element in the third intron of the PRDM1 (BLIMP1) gene stimulates BLIMP1 transcription (Yan et al. 2007).

Literature References

PubMed ID	Title	Journal	Year
17264218	BLIMP1 regulates cell growth through repression of p53 transcription Yan, J, Jiang, J, Lim, CA, Wu, Q, Ng, HH, Chin, KC	Proc. Natl. Acad. Sci. U.S.A.	2007