N2O3 diffuses to phagosome

Stable Identifier
Reaction [BlackBoxEvent]
Homo sapiens
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The uncharged N2O3 molecule is thought to be able to diffuse through the cell membrane (Grisham MB et al. 1999; Basu S et al. 2007)

Literature References
PubMed ID Title Journal Year
9950804 Nitric oxide. I. Physiological chemistry of nitric oxide and its metabolites:implications in inflammation

Grisham, MB, Jourd'Heuil, D, Wink, DA

Am. J. Physiol. 1999
9741580 Chemical biology of nitric oxide: Insights into regulatory, cytotoxic, and cytoprotective mechanisms of nitric oxide

Mitchell, JB, Wink, DA

Free Radic. Biol. Med. 1998
17982448 Catalytic generation of N2O3 by the concerted nitrite reductase and anhydrase activity of hemoglobin

Gladwin, MT, Patel, R, Kim-Shapiro, DB, King, SB, Huang, J, Hogg, N, Mehta, A, Seibert, R, Azarov, I, Basu, S, Jiang, A, Huang, Z, Grubina, R, Ghosh, A, Jeffers, A, Conradie, J, He, X

Nat. Chem. Biol. 2007
11697121 The mechanisms for nitration and nitrotyrosine formation in vitro and in vivo: impact of diet

Rice-Evans, C, Oldreive, C

Free Radic. Res. 2001
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