TP53 stimulates ZNF385A transcription

Stable Identifier
R-HSA-6803437
Type
Reaction [omitted]
Species
Homo sapiens
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Binding of TP53 (p53) to the p53 response element(s) in the promoter of the ZNF385A (HZF) gene stimulates ZNF385A transcription (Das et al. 2007). TP53-mediated induction of ZNF385A is conserved in mouse (Sugimoto et al. 2006, Das et al. 2007).

Literature References
PubMed ID Title Journal Year
16382142 Hzf, a p53-responsive gene, regulates maintenance of the G2 phase checkpoint induced by DNA damage

Sugimoto, M, Gromley, A, Sherr, CJ

Mol. Cell. Biol. 2006
17719541 Hzf Determines cell survival upon genotoxic stress by modulating p53 transactivation

Das, S, Raj, L, Zhao, B, Kimura, Y, Bernstein, A, Aaronson, SA, Lee, SW

Cell 2007
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