high kinase activity BRAF mutants [cytosol]

Stable Identifier
R-HSA-6802579
Type
Set [DefinedSet]
Species
Homo sapiens
Compartment
cytosol
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Literature References
PubMed ID Title Journal Year
15035987 Mechanism of activation of the RAF-ERK signaling pathway by oncogenic mutations of B-RAF

Niculescu-Duvaz, D, Lee, S, Marais, R, Marshall, CJ, Barford, D, Jones, CM, Good, VM, Springer, CJ, Wan, PT, Garnett, MJ, Roe, SM

Cell 2004
18413255 Biochemical characterization of novel germline BRAF and MEK mutations in cardio-facio-cutaneous syndrome

Rodriguez-Viciana, P, Rauen, KA

Meth. Enzymol. 2008
Participants
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Participates
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Disease
Name Identifier Synonyms
cardiofaciocutaneous syndrome DOID:0060233 CFC syndrome, cardio-facial-cutaneous syndrome
cancer DOID:162 malignant tumor, malignant neoplasm, primary cancer
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