p-ESRP1-RAF1 fusion [cytosol]

Stable Identifier
R-HSA-6802523
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Literature References
PubMed ID Title Journal Year
20526349 Rearrangements of the RAF kinase pathway in prostate cancer, gastric cancer and melanoma

Palanisamy, N, Ateeq, B, Kalyana-Sundaram, S, Pflueger, D, Ramnarayanan, K, Shankar, S, Han, B, Cao, Q, Cao, X, Suleman, K, Kumar-Sinha, C, Dhanasekaran, SM, Chen, YB, Esgueva, R, Banerjee, S, Lafargue, CJ, Siddiqui, J, Demichelis, F, Moeller, P, Bismar, TA, Kuefer, R, Fullen, DR, Johnson, TM, Greenson, JK, Giordano, TJ, Tan, P, Tomlins, SA, Varambally, S, Rubin, MA, Maher, CA, Chinnaiyan, AM

Nat. Med. 2010
External Reference Information
External Reference
UniProt:Q6NXG1 ESRP1
Gene Names
ESRP1, RBM35A
Chain
chain:1-681
Reference Genes
BioGPS Gene:54845 ESRP1
COSMIC (genes):ESRP1 ESRP1
CTD Gene:54845 ESRP1
dbSNP Gene:54845 ESRP1
ENSEMBL:ENSG00000104413 ESRP1
HGNC:25966 ESRP1
KEGG Gene (Homo sapiens):54845 ESRP1
Monarch:54845 ESRP1
NCBI Gene:54845 ESRP1
OMIM:612959 ESRP1
UCSC:Q6NXG1 ESRP1
Reference Transcript
Other Identifiers
0000070402
11723543_a_at
11723544_a_at
17070949
219121_s_at
225846_at
23719
23720
2DHA
2RVJ
3107549
3107550
3107552
3107554
3107555
3107563
3107564
3107565
3107566
3107567
3107568
3107570
3107571
3107578
3107585
3107586
3107587
3107590
3107593
3107594
3631959
50391_at
54845
67104
8147351
82072_at
A0A2U3TZN9
A_14_P135791
A_23_P259127
AAH19932
AAH67098
AAH99916
AAI12044
AC108860
AK000178
AP005660
BAA90992
BC019932
BC067098
BC099916
BC112043
BX647570
CCDS47895
CCDS47896
CCDS47897
CCDS47898
ENSG00000104413
ENSP00000351168
ENSP00000405738
ENSP00000407349
ENSP00000494213
ENST00000358397
ENST00000358397.9
ENST00000423620
ENST00000423620.6
ENST00000433389
ENST00000642581.1
ENST00000646773
ENST00000646773.1
EntrezGene:54845
EntrezGene:ESRP1
ESRP1
ESRP1-201
ESRP1-202
ESRP1-203
ESRP1-212
g8923166_3p_a_at
GE55386
GO:0003674
GO:0003676
GO:0003723
GO:0003729
GO:0005515
GO:0005575
GO:0005622
GO:0005623
GO:0005634
GO:0005654
GO:0006397
GO:0007165
GO:0008150
GO:0008380
GO:0008543
GO:0016604
GO:0030154
GO:0034641
GO:0042669
GO:0043226
GO:0043484
GO:0048856
H0YBB3
HGNC:25966
HPA023719
HPA023720
HPA067104
Hs.24743.1.A1_3p_at
ILMN_1749180
IPR000504
IPR012337
IPR012677
IPR034427
IPR035979
IPR036397
MIM:612959
MIM:618013
NM_001034915
NM_001122825
NM_001122826
NM_017697
NP_001030087
NP_001116297
NP_001116298
NP_060167
PH_hs_0002178
SM00360
TC08000575.hg
UPI0000210327
UPI0000D4983D
UPI0000E21BA9
UPI0000ED8FDA
XM_005250991
XM_005250992
XP_005251048
XP_005251049
Participant Of
hasComponent
Other forms of this molecule
ESRP1-RAF1 fusion [cytosol]
ESRP1 [nucleoplasm]
Modified Residues
Name
Insertion of residues 227 to 648 at 607 from UniProt:P04049 RAF1
Coordinate
607
Name
O-phospho-L-serine at 621
Coordinate
621
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-serine at 338
Coordinate
338
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O4'-phospho-L-tyrosine at 341
Coordinate
341
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O-phospho-L-threonine at 491
Coordinate
491
PsiMod Name
O-phospho-L-threonine [MOD:00047]
PsiMod Definition
A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.
Name
O-phospho-L-serine at 494
Coordinate
494
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Disease
Name Identifier Synonyms
prostate cancer 10283 NGP - New growth of prostate, neoplasm of prostate (disorder), tumor of the prostate, malignant tumor of prostate (disorder), prostate neoplasm, malignant tumor of the prostate, malignant tumor of prostate (disorder), prostatic cancer, prostatic neoplasm
cancer 162 malignant tumor, malignant neoplasm, primary cancer
Cross References
RefSeq
OpenTargets
GeneCards
PRO
PDB
Interactors (9)