AGK(1-33)InsW-p-BRAF(328-766) fusion [cytosol]

Stable Identifier
R-HSA-6802510
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Locations in the PathwayBrowser
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Literature References
PubMed ID Title Journal Year
24135138 Identification of kinase fusion oncogenes in post-Chernobyl radiation-induced thyroid cancers

Fagin, JA, Thomas, GA, Viale, A, Ricarte-Filho, JC, Voza, F, Bogdanova, T, Knauf, JA, Montero-Conde, C, Li, S, Garcia-Rendueles, ME, Heguy, A, Mason, CE

J. Clin. Invest. 2013
External Reference Information
External Reference
UniProt:Q53H12 AGK
Gene Names
AGK, MULK
Chain
chain:1-422
Reference Genes
BioGPS Gene:55750 Q53H122
COSMIC (genes):AGK AGK
CTD Gene:55750 Q53H122
dbSNP Gene:55750 Q53H122
ENSEMBL:ENSG00000006530 AGK
ENSEMBL:ENSG00000262327 AGK
HGNC:21869 Q53H122
KEGG:hsa:55750 Q53H122
Monarch:55750 Q53H122
NCBI Gene:55750 Q53H122
OMIM:610345 Q53H122
UCSC:Q53H12 Q53H122
Reference Transcript
Participates
as a component of
Other forms of this molecule
AGK [mitochondrial outer membrane]
AGK(1-33)InsW-BRAF(328-766) fusion [cytosol]
Modified Residues
Name
Insertion of residues 328 to 766 at 34 from UniProt:P15056 BRAF
Coordinate
34
Name
Replacement of residues 33 to 33 by HW
Name
O-phospho-L-serine at 446
Coordinate
446
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-serine at 729
Coordinate
729
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-threonine at 599
Coordinate
599
PsiMod Name
O-phospho-L-threonine [MOD:00047]
PsiMod Definition
A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.
Name
O-phospho-L-serine at 602
Coordinate
602
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Disease
Name Identifier Synonyms
thyroid cancer DOID:1781 Thyroid gland neoplasm, thyroid cancer, thyroid neoplasm, neoplasm of thyroid gland, thyroid neoplasm, Thyroid neoplasm, malignant tumour of thyroid gland, malignant neoplasm of thyroid gland
Cross References
ENSEMBL
OpenTargets
GeneCards
AGK
HPA
PRO
Pharos - Targets
Orphanet
AGK
HMDB Protein
PDB
Interactors (4)
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