AGGF(1-290)-p-RAF1(279-648) fusion [cytosol]

Stable Identifier
R-HSA-6802507
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Locations in the PathwayBrowser
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Literature References
PubMed ID Title Journal Year
25204415 The landscape of kinase fusions in cancer

Stransky, N, Cerami, E, Schalm, S, Kim, JL, Lengauer, C

Nat Commun 2014
External Reference Information
External Reference
UniProt:Q8N302 AGGF1
Gene Names
AGGF1, GPATC7, GPATCH7, VG5Q
Chain
initiator methionine:1, chain:2-714
Reference Genes
BioGPS Gene:55109 Q8N3022
COSMIC (genes):AGGF1 AGGF1
CTD Gene:55109 Q8N3022
dbSNP Gene:55109 AGGF1
ENSEMBL:ENSG00000164252 AGGF1
HGNC:24684 Q8N3022
KEGG:hsa:55109 Q8N3022
Monarch:55109 Q8N3022
NCBI Gene:55109 Q8N3022
OMIM:608464 Q8N3022
UCSC:Q8N302 Q8N3022
Reference Transcript
Participates
as a component of
Other forms of this molecule
AGGF(1-290)-RAF1(279-648) fusion [cytosol]
Modified Residues
Name
Insertion of residues 279 to 648 at 291 from UniProt:P04049 RAF1
Coordinate
291
Name
O-phospho-L-serine at 621
Coordinate
621
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-serine at 338
Coordinate
338
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O4'-phospho-L-tyrosine at 341
Coordinate
341
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O-phospho-L-threonine at 491
Coordinate
491
PsiMod Name
O-phospho-L-threonine [MOD:00047]
PsiMod Definition
A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.
Name
O-phospho-L-serine at 494
Coordinate
494
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Disease
Name Identifier Synonyms
prostate adenocarcinoma DOID:2526 adenocarcinoma of prostate (disorder), prostate adenocarcinoma
thyroid carcinoma DOID:3963 head and neck cancer, Thyroid
cancer DOID:162 malignant tumor, malignant neoplasm, primary cancer
Cross References
RefSeq
ENSEMBL
OpenTargets
Mondo
GeneCards
HPA
PRO
Pharos - Targets
Orphanet
Interactors (4)
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