PAPSS1-BRAF fusion [cytosol]

Stable Identifier
R-HSA-6802432
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Literature References
PubMed ID Title Journal Year
24345920 BRAF fusions define a distinct molecular subset of melanomas with potential sensitivity to MEK inhibition

Hutchinson, KE, Lipson, D, Stephens, PJ, Otto, G, Lehmann, BD, Lyle, PL, Vnencak-Jones, CL, Ross, JS, Pietenpol, JA, Sosman, JA, Puzanov, I, Miller, VA, Pao, W

Clin. Cancer Res. 2013
External Reference Information
External Reference
Gene Names
PAPSS1, ATPSK1, PAPSS
Chain
chain:1-624
Other Identifiers
0002360528
11727372_at
11727373_s_at
11751595_a_at
16978793
209043_at
2781002
2781003
2781004
2781005
2781019
2781020
2781022
2781026
2781027
2781028
2781029
2781030
2781031
2781032
2781033
2781034
2781035
2781041
2781042
34411_at
8102214
9061
A_23_P144465
GE54804
GO:0000103
GO:0000166
GO:0001501
GO:0003674
GO:0003824
GO:0004020
GO:0004781
GO:0005524
GO:0005575
GO:0005622
GO:0005737
GO:0005829
GO:0006790
GO:0008150
GO:0008152
GO:0009058
GO:0016301
GO:0016310
GO:0016740
GO:0016779
GO:0034641
GO:0042803
GO:0043167
GO:0044281
GO:0048856
GO:0050428
ILMN_1781819
ILMN_2224103
PH_hs_0027050
TC04001455.hg
g3378100_3p_at
Participant Of
Other forms of this molecule
Modified Residues
Name
Insertion of residues 381 to 766 at 224 from UniProt:P15056 BRAF
Coordinate
224
Name
O-phospho-L-serine at 445
Coordinate
445
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-serine at 729
Coordinate
729
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Disease
Name Identifier Synonyms
cancer 162 malignant tumor, malignant neoplasm, primary cancer
melanoma 1909 Naevocarcinoma, melanoma, melanoma, malignant melanoma, morphology (morphologic abnormality), malignant melanoma NOS (morphologic abnormality), malignant melanoma (disorder), malignant melanoma, malignant melanoma, malignant melanoma, malignant melanoma
Cross References
OpenTargets
GeneCards
PRO
Orphanet
HMDB Protein
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