KDM7A(1-476)-BRAF(439-766) fusion [cytosol]

Stable Identifier
R-HSA-6802391
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Literature References
PubMed ID Title Journal Year
25204415 The landscape of kinase fusions in cancer

Kim, JL, Schalm, S, Stransky, N, Lengauer, C, Cerami, E

Nat Commun 2014
External Reference Information
External Reference
UniProt:Q6ZMT4 KDM7A
Gene Names
KDM7A, JHDM1D, KDM7, KIAA1718
Chain
chain:1-941
Reference Genes
BioGPS Gene:80853 KDM7A
COSMIC (genes):KDM7A KDM7A
CTD Gene:80853 KDM7A
dbSNP Gene:80853 KDM7A
ENSEMBL:ENSG00000006459 KDM7A
HGNC:22224 KDM7A
KEGG:hsa:80853 KDM7A
Monarch:80853 KDM7A
NCBI Gene:80853 KDM7A
OMIM:619640 KDM7A
UCSC:Q6ZMT4 KDM7A
Reference Transcript
Other Identifiers
11753717_a_at
11755223_a_at
17063507
221778_PM_at
221778_at
225142_PM_at
225142_at
3075979
3075980
3075981
3075983
3075985
3075986
3075987
3075988
3075989
3075991
3075993
3075994
3075995
3075996
3075997
3075998
3075999
3076003
3076004
3076005
3076006
3076007
3076010
3076011
3076015
3076017
3076018
3076021
3076022
3076025
3076027
3076038
32910_at
54435_r_at
59152_at
78471_at
80853
8143341
A_23_P359897
A_33_P3252068
GE470816
GE483836
GO:0003712
GO:0003824
GO:0005506
GO:0005634
GO:0005654
GO:0005730
GO:0006325
GO:0006338
GO:0006355
GO:0006357
GO:0007399
GO:0008270
GO:0016491
GO:0016706
GO:0030901
GO:0032452
GO:0032454
GO:0035064
GO:0035575
GO:0042393
GO:0043226
GO:0045893
GO:0046872
GO:0048856
GO:0051213
GO:0051864
GO:0060090
GO:0071558
GO:0140096
GO:0140110
GO:0140683
GO:0141052
HMNXSV003053608
Hs.222707.0.A1_3p_at
Hs.222707.0.A2_3p_at
ILMN_1898639
PH_hs_0007356
PH_hs_0012489
TC07001917.hg
Participates
as a component of
Other forms of this molecule
KDM7A [nucleoplasm]
KDM7A(1-476)-p-BRAF(439-766) fusion [cytosol]
Modified Residues
Name
Insertion of residues 439 to 766 at 477 from UniProt:P15056 BRAF
Coordinate
477
Name
O-phospho-L-serine at 446
Coordinate
446
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-serine at 729
Coordinate
729
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Disease
Name Identifier Synonyms
prostate adenocarcinoma DOID:2526 adenocarcinoma of prostate (disorder), prostate adenocarcinoma
cancer DOID:162 malignant tumor, malignant neoplasm, primary cancer
Cross References
RefSeq
Guide to Pharmacology - Targets
ENSEMBL
OpenTargets
HPA
ZINC - Substances
ZINC - Biogenic
ZINC target
PRO
Pharos - Targets
ZINC - Predictions - Purchasable
PDB
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