ATG7(1-693)-BRAF(381-766) fusion [cytosol]

Stable Identifier
R-HSA-6802272
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Locations in the PathwayBrowser
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Literature References
PubMed ID Title Journal Year
25204415 The landscape of kinase fusions in cancer

Kim, JL, Schalm, S, Stransky, N, Lengauer, C, Cerami, E

Nat Commun 2014
External Reference Information
External Reference
UniProt:O95352 ATG7
Gene Names
ATG7, APG7L
Chain
initiator methionine:, chain:2-703
Reference Genes
COSMIC (genes):ATG7 ATG7
dbSNP Gene:10533 ATG7
ENSEMBL:ENSG00000197548 ATG7
Participates
as a component of
Other forms of this molecule
ATG7 [ficolin-1-rich granule lumen]
ATG7 [extracellular region]
ATG7 [secretory granule lumen]
ATG7(1-693)-p-BRAF(381-766) fusion [cytosol]
CysO572-ATG7-MAP1LC3B [cytosol]
CysO572-ATG7-GARABAPL2 [cytosol]
CysO572-ATG7-GARABAP [cytosol]
CysO572-ATG7-GARABAPL1 [cytosol]
CysO572-ATG7-MAP1LC3C [cytosol]
CysO572-ATG7-MAP1LC3A [cytosol]
CysO572-ATG7-GARABAPL3 [cytosol]
CysO572-ATG7 [cytosol]
ATG7 [cytosol]
Modified Residues
Name
Insertion of residues 381 to 766 at 694 from UniProt:P15056 BRAF
Coordinate
694
Name
O-phospho-L-serine at 446
Coordinate
446
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-serine at 729
Coordinate
729
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Disease
Name Identifier Synonyms
cancer DOID:162 malignant tumor, malignant neoplasm, primary cancer
skin melanoma DOID:8923 malignant lip melanoma, malignant ear melanoma, malignant melanoma of ear and/or external auricular canal, cutaneous melanoma, malignant melanoma of skin of trunk except scrotum, malignant neck melanoma, malignant melanoma of skin of upper limb, malignant scalp melanoma, malignant upper limb melanoma, malignant lower limb melanoma, malignant melanoma of skin of lower limb, malignant trunk melanoma
Interactors (8)
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