ATG7(1-693)-BRAF(381-766) fusion [cytosol]

Stable Identifier
R-HSA-6802272
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Literature References
PubMed ID Title Journal Year
25204415 The landscape of kinase fusions in cancer

Kim, JL, Schalm, S, Stransky, N, Lengauer, C, Cerami, E

Nat Commun 2014
External Reference Information
External Reference
UniProt:O95352 ATG7
Gene Names
ATG7, APG7L
Chain
initiator methionine:1, chain:2-703
Reference Genes
BioGPS Gene:10533 ATG7
COSMIC (genes):ATG7 ATG7
CTD Gene:10533 ATG7
dbSNP Gene:10533 ATG7
ENSEMBL:ENSG00000197548 ATG7
ENSEMBL:ENSG00000197548.13 ATG7
HGNC:16935 ATG7
KEGG Gene (Homo sapiens):10533 ATG7
Monarch:10533 ATG7
NCBI Gene:10533 ATG7
OMIM:608760 ATG7
UCSC:O95352 ATG7
Reference Transcript
Other Identifiers
10533
11727027_a_at
11740814_a_at
11750782_a_at
16937681
218673_PM_s_at
218673_s_at
222709_PM_at
222709_at
224025_PM_s_at
224025_s_at
2610733
2610735
2610736
2610737
2610738
2610742
2610743
2610746
2610749
2610750
2610752
2610756
2610758
2610759
2610761
2610762
2610764
2610771
2610772
2610773
2610774
2610777
2610784
2610831
2610832
2610833
2610834
2610835
2610836
2610837
2610838
2610839
2610840
2610841
2610842
2610843
2610844
44129_at
8077858
A_14_P105554
A_14_P200647
A_23_P143987
A_24_P944827
GE62471
GO:0000407
GO:0000422
GO:0003824
GO:0005515
GO:0005576
GO:0005737
GO:0005829
GO:0005856
GO:0005929
GO:0005930
GO:0006497
GO:0006501
GO:0006914
GO:0006995
GO:0007005
GO:0008641
GO:0009267
GO:0012501
GO:0015031
GO:0016236
GO:0016874
GO:0019778
GO:0019779
GO:0030163
GO:0031401
GO:0031410
GO:0032446
GO:0034727
GO:0034774
GO:0036211
GO:0042752
GO:0042803
GO:0043065
GO:0043226
GO:0044805
GO:0045732
GO:0048511
GO:0051607
GO:0071455
GO:0098542
GO:0140096
GO:1904813
HMNXSV003043302
HMNXSV003057907
Hs.278607.0.S2_3p_at
ILMN_1790978
PH_hs_0014291
TC03000065.hg
g5453667_3p_a_at
Participates
as a component of
Other forms of this molecule
ATG7 [secretory granule lumen]
ATG7 [extracellular region]
ATG7 [ficolin-1-rich granule lumen]
ATG7(1-693)-p-BRAF(381-766) fusion [cytosol]
CysO572-ATG7-MAP1LC3B [cytosol]
CysO572-ATG7-GARABAPL2 [cytosol]
CysO572-ATG7-GARABAP [cytosol]
CysO572-ATG7-GARABAPL1 [cytosol]
CysO572-ATG7-MAP1LC3C [cytosol]
CysO572-ATG7-MAP1LC3A [cytosol]
CysO572-ATG7-GARABAPL3 [cytosol]
CysO572-ATG7 [cytosol]
ATG7 [cytosol]
Modified Residues
Name
Insertion of residues 381 to 766 at 694 from UniProt:P15056 BRAF
Coordinate
694
Name
O-phospho-L-serine at 446
Coordinate
446
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-serine at 729
Coordinate
729
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Disease
Name Identifier Synonyms
cancer DOID:162 malignant tumor, malignant neoplasm, primary cancer
skin melanoma DOID:8923 malignant lip melanoma, malignant ear melanoma, malignant melanoma of ear and/or external auricular canal, cutaneous melanoma, malignant melanoma of skin of trunk except scrotum, malignant neck melanoma, malignant melanoma of skin of upper limb, malignant scalp melanoma, malignant upper limb melanoma, malignant lower limb melanoma, malignant melanoma of skin of lower limb, malignant trunk melanoma
Cross References
RefSeq
OpenTargets
HPA
GeneCards
ZINC target
Ensembl
PRO
Pharos - Targets
Interactors (5)
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