AGK(1-33)InsW-BRAF(328-766) fusion [cytosol]

Stable Identifier
R-HSA-6802260
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Literature References
PubMed ID Title Journal Year
24135138 Identification of kinase fusion oncogenes in post-Chernobyl radiation-induced thyroid cancers

Fagin, JA, Thomas, GA, Viale, A, Ricarte-Filho, JC, Voza, F, Bogdanova, T, Knauf, JA, Montero-Conde, C, Li, S, Garcia-Rendueles, ME, Heguy, A, Mason, CE

J. Clin. Invest. 2013
External Reference Information
External Reference
UniProt:Q53H12 AGK
Gene Names
AGK, MULK
Chain
chain:1-422
Reference Genes
BioGPS Gene:55750 AGK
COSMIC (genes):AGK AGK
CTD Gene:55750 AGK
dbSNP Gene:55750 AGK
ENSEMBL:ENSG00000006530 AGK
ENSEMBL:ENSG00000006530.18 AGK
ENSEMBL:ENSG00000262327 AGK
ENSEMBL:ENSG00000262327.7 AGK
HGNC:21869 AGK
KEGG Gene (Homo sapiens):55750 AGK
Monarch:55750 AGK
NCBI Gene:55750 AGK
OMIM:610345 AGK
UCSC:Q53H12 AGK
Reference Transcript
Other Identifiers
0004780519
11739123_at
11739124_a_at
11762881_at
1555610_PM_at
1555610_at
17052353
218568_PM_at
218568_at
222132_PM_s_at
222132_s_at
3027723
3027813
3027814
3027815
3027817
3027818
3027819
3027821
3027823
3027824
3027825
3027826
3027829
3027830
3027831
3027833
3027834
3027835
3027837
3027838
3027840
3027841
3027842
3027843
3027844
3027854
4022079
52142_at
55750
8136614
A_23_P309224
A_24_P917729
GE79633
GO:0000166
GO:0001727
GO:0001729
GO:0004143
GO:0005515
GO:0005524
GO:0005622
GO:0005737
GO:0005739
GO:0005741
GO:0005743
GO:0005758
GO:0005829
GO:0006629
GO:0006665
GO:0006886
GO:0007005
GO:0016020
GO:0016301
GO:0016310
GO:0016740
GO:0031305
GO:0031966
GO:0032991
GO:0042721
GO:0043226
GO:0043231
GO:0045039
GO:0046486
GO:0046513
GO:0046834
GO:0047620
GO:0061024
GO:0102773
HMNXSV003010813
Hs.260238.2.S1_3p_a_at
Hs2.434210.1.S1_3p_at
ILMN_1772645
TC07000889.hg
g8922700_3p_at
Participates
as a component of
Other forms of this molecule
AGK [mitochondrial outer membrane]
AGK(1-33)InsW-p-BRAF(328-766) fusion [cytosol]
Modified Residues
Name
Insertion of residues 328 to 766 at 34 from UniProt:P15056 BRAF
Coordinate
34
Name
O-phospho-L-serine at 445
Coordinate
445
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-serine at 729
Coordinate
729
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Disease
Name Identifier Synonyms
thyroid cancer DOID:1781 Thyroid gland neoplasm, thyroid cancer, thyroid neoplasm, neoplasm of thyroid gland, thyroid neoplasm, Thyroid neoplasm, malignant tumour of thyroid gland, malignant neoplasm of thyroid gland
Cross References
RefSeq
OpenTargets
HPA
GeneCards
Ensembl
PRO
Pharos - Targets
Orphanet
PDB
HMDB Protein
Interactors (1)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:P42858 HTT  1 0.556 3
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