AGK-BRAF fusion [cytosol]

Stable Identifier
R-HSA-6802260
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Literature References
PubMed ID Title Journal Year
24135138 Identification of kinase fusion oncogenes in post-Chernobyl radiation-induced thyroid cancers

Ricarte-Filho, JC, Li, S, Garcia-Rendueles, ME, Montero-Conde, C, Voza, F, Knauf, JA, Heguy, A, Viale, A, Bogdanova, T, Thomas, GA, Mason, CE, Fagin, JA

J. Clin. Invest. 2013
External Reference Information
External Reference
UniProt:Q53H12 AGK
Gene Names
AGK, MULK
Chain
chain:1-422
Reference Genes
BioGPS Gene:55750 AGK
COSMIC (genes):AGK AGK
CTD Gene:55750 AGK
dbSNP Gene:55750 AGK
ENSEMBL:ENSG00000006530 AGK
ENSEMBL:ENSG00000262327 AGK
HGNC:21869 AGK
KEGG Gene (Homo sapiens):55750 AGK
Monarch:55750 AGK
NCBI Gene:55750 AGK
OMIM:610345 AGK
UCSC:Q53H12 AGK
Reference Transcript
Other Identifiers
0004780519
11739123_at
11739124_a_at
11762881_at
1555610_at
17052353
218568_at
222132_s_at
3027723
3027813
3027814
3027815
3027817
3027818
3027819
3027821
3027823
3027824
3027825
3027826
3027829
3027830
3027831
3027833
3027834
3027835
3027837
3027838
3027840
3027841
3027842
3027843
3027844
3027854
4022079
52142_at
55750
8136614
A0A0G2JLD0
A0A0G2JLG5
A0A3B3IRM6
A0A3B3IS09
A0A3B3ISY9
A0A3B3ISZ0
A0A3B3ITD0
A0A3B3ITV0
A0A3B3ITX7
A0A3B3IUC9
A4D1U5
A_23_P309224
A_24_P917729
AAH09775
AAH22777
AAS07537
AC004918
AC073878
AC099547
AGK
AGK-204
AGK-213
AGK-218
AGK-225
AGK-229
AJ278150
AK001704
AK222769
BAA91848
BAD96489
BC009775
BC022777
CAB93536
CCDS5865
CH236950
CH471070
E9PC15
E9PG39
EAL24020
EAW83972
ENSG00000006530
ENSG00000262327
ENSP00000418789
ENSP00000458417
ENSP00000496789
ENSP00000497280
ENSP00000498112
ENST00000355413.8
ENST00000492693
ENST00000492693.5
ENST00000575872
ENST00000648068
ENST00000648068.1
ENST00000649286
ENST00000650547
ENST00000650547.1
EntrezGene:55750
EntrezGene:AGK
F8WDD1
FLJ10842
g8922700_3p_at
GE79633
GO:0000166
GO:0001727
GO:0001729
GO:0003674
GO:0003951
GO:0004143
GO:0005524
GO:0005575
GO:0005622
GO:0005623
GO:0005737
GO:0005739
GO:0005741
GO:0005743
GO:0005758
GO:0005829
GO:0006605
GO:0006629
GO:0006810
GO:0007005
GO:0008150
GO:0009058
GO:0015031
GO:0016020
GO:0016301
GO:0016310
GO:0016740
GO:0031305
GO:0031966
GO:0032991
GO:0034641
GO:0042721
GO:0043167
GO:0043226
GO:0043231
GO:0045039
GO:0046474
GO:0046486
GO:0046513
GO:0046834
GO:0047620
GO:0061024
GO:0102773
HGNC:21869
HPA020959
HPA053471
Hs.260238.2.S1_3p_a_at
Hs2.434210.1.S1_3p_at
ILMN_1772645
IPR001206
IPR016064
IPR017438
LRG_1251
MIM:212350
MIM:610345
MIM:614691
NM_001364948
NM_018238
NP_001351877
NP_060708
PF00781
SM00046
TC07000889.hg
UPI000006E622
UPI00000704D5
UPI0004620BE5
XM_011516397
XM_024446835
XP_011514699
XP_024302603
Participant Of
hasComponent
Other forms of this molecule
AGK [mitochondrial outer membrane]
p-AGK-BRAF fusion [cytosol]
Modified Residues
Name
Insertion of residues 327 to 766 at 34 from UniProt:P15056 BRAF
Coordinate
34
Name
O-phospho-L-serine at 445
Coordinate
445
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-serine at 729
Coordinate
729
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Disease
Name Identifier Synonyms
thyroid cancer 1781 Thyroid gland neoplasm, thyroid cancer, thyroid neoplasm, neoplasm of thyroid gland, thyroid neoplasm, Thyroid neoplasm, malignant tumour of thyroid gland, malignant neoplasm of thyroid gland
Cross References
RefSeq
OpenTargets
GeneCards
PRO
Orphanet
HMDB Protein