AGGF(1-290)-RAF1(279-648) fusion [cytosol]

Stable Identifier
R-HSA-6802255
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Literature References
PubMed ID Title Journal Year
25204415 The landscape of kinase fusions in cancer

Kim, JL, Schalm, S, Stransky, N, Lengauer, C, Cerami, E

Nat Commun 2014
External Reference Information
External Reference
UniProt:Q8N302 AGGF1
Gene Names
AGGF1, GPATC7, GPATCH7, VG5Q
Chain
initiator methionine:, chain:2-714
Reference Genes
BioGPS Gene:55109 Q8N3022
COSMIC (genes):AGGF1 AGGF1
CTD Gene:55109 Q8N3022
dbSNP Gene:55109 Q8N3022
ENSEMBL:ENSG00000164252 AGGF1
HGNC:24684 Q8N3022
KEGG:hsa:55109 Q8N3022
Monarch:55109 Q8N3022
NCBI Gene:55109 Q8N3022
OMIM:608464 Q8N3022
UCSC:Q8N302 Q8N3022
Reference Transcript
Participates
as a component of
Other forms of this molecule
AGGF(1-290)-p-RAF1(279-648) fusion [cytosol]
Modified Residues
Name
Insertion of residues 279 to 648 at 291 from UniProt:P04049 RAF1
Coordinate
291
Name
O-phospho-L-serine at 621
Coordinate
621
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Disease
Name Identifier Synonyms
prostate adenocarcinoma DOID:2526 adenocarcinoma of prostate (disorder), prostate adenocarcinoma
thyroid carcinoma DOID:3963 head and neck cancer, Thyroid
cancer DOID:162 malignant tumor, malignant neoplasm, primary cancer
Cross References
ENSEMBL
OpenTargets
GeneCards
HPA
PRO
Pharos - Targets
Orphanet
Interactors (4)
Cite Us!