Reactome | HK3 [ficolin-1-rich granule lumen]

HK3 [ficolin-1-rich granule lumen]

Stable Identifier

R-HSA-6801527

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

ficolin-1-rich granule lumen

Synonyms

hexokinase 3, hexokinase type 3, hexokinase leukocyte form, HXK3_HUMAN, Hexokinase type III , HK III

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:P52790 HK3

Gene Names

HK3

Chain

chain:1-923

Reference Genes

BioGPS Gene:3101 HK3

COSMIC (genes):HK3 HK3

CTD Gene:3101 HK3

dbSNP Gene:3101 HK3

ENSEMBL:ENSG00000160883 HK3

HGNC:4925 HK3

KEGG:hsa:3101 HK3

Monarch:3101 HK3

NCBI Gene:3101 HK3

OMIM:142570 HK3

UCSC:P52790 HK3

Reference Transcript

RefSeq:NM_002115.2 HK3

Other Identifiers

11757186_a_at

17003124

205936_PM_s_at

205936_s_at

2888486

2888487

2888488

2888489

2888490

2888491

2888492

2888493

2888494

2888495

2888496

2888497

2888498

2888499

2888500

2888501

2888502

2888503

2888505

2888506

2888507

2888508

2888509

2888510

2888511

2888512

2888514

2888515

2888516

3101

36372_at

8115957

A_23_P213584

A_24_P37962

GE62519

GO:0001678

GO:0003824

GO:0004340

GO:0004396

GO:0005515

GO:0005524

GO:0005536

GO:0005576

GO:0005739

GO:0005829

GO:0005975

GO:0006002

GO:0006006

GO:0006091

GO:0006096

GO:0008865

GO:0016301

GO:0016740

GO:0016773

GO:0019318

GO:0034774

GO:0043226

GO:0046835

GO:0051156

GO:0055086

GO:0061621

GO:1901135

GO:1904813

HMNXSV003048843

ILMN_1670302

PH_hs_0024879

TC05002100.hg

U51333_s_at

g4504394_3p_a_at

Participates

as a member of

Ficolin-rich granule lumen proteins [ficolin-1-rich granule lumen] (Homo sapiens)

Other forms of this molecule

HK3 [secretory granule lumen]

HK3 [extracellular region]

HK3 [cytosol]

Inferred To

hk1 [ficolin-1-rich granule lumen] (Danio rerio)

HK3 [ficolin-1-rich granule lumen] (Bos taurus)

HK3 [ficolin-1-rich granule lumen] (Canis familiaris)

HK3 [ficolin-1-rich granule lumen] (Drosophila melanogaster)

HK3 [ficolin-1-rich granule lumen] (Gallus gallus)

HK3 [ficolin-1-rich granule lumen] (Mus musculus)

HK3 [ficolin-1-rich granule lumen] (Plasmodium falciparum)

HK3 [ficolin-1-rich granule lumen] (Rattus norvegicus)

HK3 [ficolin-1-rich granule lumen] (Saccharomyces cerevisiae)

HK3 [ficolin-1-rich granule lumen] (Schizosaccharomyces pombe)

HK3 [ficolin-1-rich granule lumen] (Sus scrofa)

hk2 [ficolin-1-rich granule lumen] (Xenopus tropicalis)

hxk-3 [ficolin-1-rich granule lumen] (Caenorhabditis elegans)

Hex-A [ficolin-1-rich granule lumen] (Drosophila melanogaster)

Hex-C [ficolin-1-rich granule lumen] (Drosophila melanogaster)

Homologues of HK3 [ficolin-1-rich granule lumen] (Caenorhabditis elegans)

Homologues of HK3 [ficolin-1-rich granule lumen] (Drosophila melanogaster)

Homologues of HK3 [ficolin-1-rich granule lumen] (Saccharomyces cerevisiae)

Homologues of HK3 [ficolin-1-rich granule lumen] (Schizosaccharomyces pombe)

hxk-1 [ficolin-1-rich granule lumen] (Caenorhabditis elegans)

hxk-2 [ficolin-1-rich granule lumen] (Caenorhabditis elegans)

Cross References

RefSeq

NP_002106.2

ENSEMBL

ENSG00000160883, ENST00000292432, ENSP00000292432

OpenTargets

ENSG00000160883

GeneCards

HK3

HPA

ENSG00000160883-HK3

PRO

P52790

Pharos - Targets

P52790

HMDB Protein

HMDBP00212

PDB

3HM8

Interactors (3)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P42858 HTT	1	HTT [nucleoplasm] (R-HSA-9023590)	0.556	3
UniProt:O76024 WFS1	3	WFS1 [endoplasmic reticulum lumen] (R-HSA-8956747) p-WFS1 [endoplasmic reticulum lumen] (R-HSA-8956998) WFS1 [endoplasmic reticulum membrane] (R-HSA-535474)	0.556	3
UniProt:P61916 NPC2	3	NPC2 [lysosomal lumen] (R-HSA-8876488) NPC2 [extracellular region] (R-HSA-6806224) NPC2 [azurophil granule lumen] (R-HSA-6799163)	0.527	2

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